Growth Metrics

Silence Therapeutics (SLN) Net Margin (2020 - 2026)

Silence Therapeutics recorded quarterly Net Margin of 3544.31% in Q1 2026, up 90.62% quarter-over-quarter from 37788.24% in Q4 2025, and up 1654724.0% year-over-year from N/an in Q1 2025.

Silence Therapeutics' Net Margin history runs 7 years deep, the most recent figure standing at 3544.31% for Q1 2026.

  • In Q1 2026, Net Margin rose 1654724.0% year-over-year to 3544.31%; the TTM figure through Mar 2026 stood at 9339.51% (down 906000.0% YoY), while the FY2025 annual figure was 16044.72%, down 1593998.0% from the prior year.
  • Net Margin came in at 3544.31% for Q1 2026 at Silence Therapeutics, up from 37788.24% in the prior quarter.
  • In the past five years, Net Margin ranged from a high of 48.61% in Q4 2024 to a low of 37788.24% in Q4 2025.
  • A 5-year average of 5661.27% and a median of 381.02% in 2023 frame the typical range for Net Margin.
  • Across the five-year window, Net Margin soared 31376401 bps in 2022 and plunged 3783685 bps in 2025, its largest moves.
  • Silence Therapeutics' Net Margin stood at 315.84% in 2022, then slumped by 126 bps to 713.01% in 2023, then jumped by 107 bps to 48.61% in 2024, then tumbled by 77830 bps to 37788.24% in 2025, then jumped by 91 bps to 3544.31% in 2026.
  • According to Business Quant data, Net Margin over the past three periods registered 3544.31%, 37788.24%, and 13181.13% for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Margin (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn 0.82%
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 34.53%
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 20.17%
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 17.65%
10 Silence Therapeutics 924.61 Mn 854.53 Mn 411,000.00 -3,544.31%

Historic Data

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DateValue
Mar 31, 2026 -3,544.31%
Dec 31, 2025 -37,788.24%
Sep 30, 2025 -13,181.13%
Jun 30, 2025 -13,677.00%
Mar 31, 2025 -20,091.55%
Dec 31, 2024 48.61%
Sep 30, 2024 -2,615.77%
Jun 30, 2024 -2,911.96%
Mar 31, 2024 -14.73%
Dec 31, 2023 -713.01%
Sep 30, 2023 -381.02%
Jun 30, 2023 -131.92%
Mar 31, 2023 -111.42%
Dec 31, 2022 -315.84%
Sep 30, 2022 -276.65%
Jun 30, 2022 -368.38%
Mar 31, 2022 -167.28%
Dec 31, 2021 -328.85%
Sep 30, 2021 -381.84%
Jun 30, 2021 -470.49%
Mar 31, 2021 -313,931.30%
Dec 31, 2020 -240.55%
Sep 30, 2020 -479,879.28%