Silence Therapeutics (SLN) Net Margin (2024 - 2026)

Silence Therapeutics (SLN) posted Net Margin of 3544.31% for Q1 2026, up 89.76% sequentially from 34617.65% in Q4 2025, and up 1654724.0% YoY from N/an in Q1 2025.

Silence Therapeutics (SLN) Net Margin (2024 - 2026) Analysis & Trends

Silence Therapeutics has reported Net Margin for 3 years, with the latest figure at 3544.31% in Q1 2026.

  • Quarterly Net Margin rose 1654724.0% year-over-year to 3544.31% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 8943.86% (down 872917.0% YoY) and the FY2025 annual result came in at 15851.88%, down 1578255.0% from the prior year.
  • Net Margin rose to 3544.31% in Q1 2026 per SLN's latest filing, from 34617.65% in the prior quarter.
  • Over five years, Net Margin peaked at 95.88% in Q4 2024 and troughed at 34617.65% in Q4 2025.
  • A 3-year average of 9823.03% and a median of 3544.31% in 2026 frame the typical range for Net Margin.
  • The sharpest annual moves came in 2025 and 2026: Net Margin sank 3471353 bps in 2025, then soared 1654724 bps in 2026.
  • Over 3 years, Net Margin stood at 95.88% in 2024, then tumbled by 36204 bps to 34617.65% in 2025, then soared by 90 bps to 3544.31% in 2026.
  • According to Business Quant data, Net Margin over the past three periods registered 3544.31%, 34617.65%, and 13181.13% for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Margin (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 32.99%
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 30.23%
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 30.33%
4 Revolution Medicines 43.64 Bn 43.64 Bn - -
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 13.90%
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn 30.98%
7 Royalty Pharma 33.72 Bn 35.84 Bn - 12.09%
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 12.74%
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -3.12%
10 Silence Therapeutics 648.22 Mn 576.12 Mn - -

Historic Data

Download Data
DateValue
Mar 31, 2026 -3,544.31%
Dec 31, 2025 -34,617.65%
Sep 30, 2025 -13,181.13%
Jun 30, 2025 -12,211.61%
Mar 31, 2025 -20,091.55%
Dec 31, 2024 95.88%
Sep 30, 2024 -2,372.76%
Jun 30, 2024 -2,469.38%
Mar 31, 2024 -14.73%