Growth Metrics

Silence Therapeutics (SLN) Change in Cash (2020 - 2026)

Silence Therapeutics recorded quarterly Change in Cash of -$5.6 million in Q1 2026, up 92.07% quarter-over-quarter from -$70.6 million in Q4 2025, and up 90.11% year-over-year from -$2.9 million in Q1 2025.

Silence Therapeutics' Change in Cash history runs 7 years deep, the most recent figure standing at -$5.6 million for Q1 2026.

  • In Q1 2026, Change in Cash rose 90.11% year-over-year to -$5.6 million; the TTM figure through Mar 2026 stood at -$59.2 million (up 23.85% YoY), while the FY2025 annual figure was -$110.2 million, down 310.07% from the prior year.
  • Change in Cash came in at -$5.6 million for Q1 2026 at Silence Therapeutics, up from -$70.6 million in the prior quarter.
  • In the past five years, Change in Cash ranged from a high of $74.0 million in Q1 2024 to a low of -$70.6 million in Q4 2025.
  • A 5-year average of -$5.0 million and a median of -$9.1 million in 2023 frame the typical range for Change in Cash.
  • On a YoY basis, Change in Cash climbed as much as 16706.5% in 2022 and fell as far as 1253.11% in 2022.
  • Silence Therapeutics' Change in Cash stood at -$34.9 million in 2022, then surged by 94.44% to -$1.9 million in 2023, then soared by 2085.72% to $38.5 million in 2024, then tumbled by 283.22% to -$70.6 million in 2025, then soared by 92.07% to -$5.6 million in 2026.
  • According to Business Quant data, Change in Cash over the past three periods registered -$5.6 million, -$70.6 million, and $40.4 million for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Change in Cash (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - 2.44 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn 623.00 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -2.44 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 417.10 Mn
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn -153.10 Mn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 53.61 Mn
10 Silence Therapeutics 924.61 Mn 854.53 Mn 411,000.00 -5.60 Mn

Historic Data

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DateValue
Mar 31, 2026 -5.60 Mn
Dec 31, 2025 -70.63 Mn
Sep 30, 2025 40.40 Mn
Jun 30, 2025 -23.35 Mn
Mar 31, 2025 -56.68 Mn
Dec 31, 2024 38.55 Mn
Sep 30, 2024 -55.26 Mn
Jun 30, 2024 -4.32 Mn
Mar 31, 2024 73.97 Mn
Dec 31, 2023 -1.94 Mn
Sep 30, 2023 35.20 Mn
Jun 30, 2023 -20.62 Mn
Mar 31, 2023 -9.13 Mn
Dec 31, 2022 -34.93 Mn
Sep 30, 2022 39.62 Mn
Jun 30, 2022 -10.47 Mn
Mar 31, 2022 -19.42 Mn
Dec 31, 2021 3.03 Mn
Sep 30, 2021 235,737.75
Jun 30, 2021 35.69 Mn
Mar 31, 2021 25.15 Mn
Dec 31, 2020 19.09 Mn
Sep 30, 2020 4.90 Mn