Sionna Therapeutics (SION) Return on Equity [ROE] (2025 - 2026)
Sionna Therapeutics (SION) posted Return on Equity [ROE] of -35.18% for Q2 2026, down 12.94 percentage points from -22.24% a year earlier and down 6.34 percentage points from the prior quarter.
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Analysis
Sionna Therapeutics (SION) Return on Equity [ROE] (2025 - 2026) Analysis & Trends
For FY2025, Sionna Therapeutics' Return on Equity [ROE] came in at -105.77%.
- The Q2 2026 figure stands as the lowest quarterly Return on Equity [ROE] since Q1 2025.
- According to Business Quant data, Return on Equity [ROE] for the three prior quarters was -28.84% (Q1 2026), -24.08% (Q4 2025) and -21.66% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROE (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 638.12 Bn | 556.64 Bn | 17.26 Bn | 25.32% |
| 2 | AbbVie | 462.60 Bn | 435.75 Bn | 12.70 Bn | - |
| 3 | Merck | 358.70 Bn | 313.13 Bn | 12.21 Bn | 7.21% |
| 4 | Novartis Ag | 272.16 Bn | 228.03 Bn | 11.24 Bn | 84.40% |
| 5 | Astrazeneca | 250.36 Bn | 223.92 Bn | 12.86 Bn | 21.39% |
| 6 | Amgen | 227.87 Bn | 183.27 Bn | 7.24 Bn | 83.75% |
| 7 | Gilead Sciences | 184.97 Bn | 159.08 Bn | 6.22 Bn | -18.38% |
| 8 | Pfizer | 162.61 Bn | 109.56 Bn | 10.94 Bn | 4.97% |
| 9 | Vertex Pharmaceuticals | 132.45 Bn | 104.46 Bn | 2.84 Bn | 22.24% |
| 10 | Sionna Therapeutics | 237.56 Mn | 237.56 Mn | - | -35.18% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -35.18% |
| Mar 31, 2026 | -28.84% |
| Dec 31, 2025 | -24.08% |
| Sep 30, 2025 | -21.66% |
| Jun 30, 2025 | -22.24% |
| Mar 31, 2025 | -71.29% |
API Access
Sionna Therapeutics Return on Equity [ROE] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=SION&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-equity-[roe]", "ticker": "SION", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=SION&period=max&api_key=YOUR_API_KEY");
const data = await res.json();