Sionna Therapeutics (SION) Return on Capital Employed (2025 - 2026)
Sionna Therapeutics (SION) posted Return on Capital Employed of 32.36% for Q1 2026, down 16.69% sequentially from 27.73% in Q4 2025, and down 362.0% YoY from 12.35% in Q1 2025.
Sionna Therapeutics (SION) Return on Capital Employed (2025 - 2026) Analysis & Trends
Sionna Therapeutics has reported Return on Capital Employed for 2 years, with the latest figure at 32.36% in Q1 2026.
- Quarterly Return on Capital Employed fell 362.0% year-over-year to 32.36% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 32.36% (down 362.0% YoY) and the FY2025 annual result came in at 36.45%, changed N/A from the prior year.
- Return on Capital Employed eased to 32.36% in Q1 2026 per SION's latest filing, from 27.73% in the prior quarter.
- Over five years, Return on Capital Employed peaked at 24.82% in Q2 2025 and troughed at 32.36% in Q1 2026.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROCE (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 128.13 Bn | 120.28 Bn | 2.84 Bn | 20.76% |
| 2 | Regeneron Pharmaceuticals | 112.33 Bn | 104.33 Bn | 3.93 Bn | 10.74% |
| 3 | Argenx Se | 53.24 Bn | 48.05 Bn | 1.41 Bn | - |
| 4 | Revolution Medicines | 43.64 Bn | 43.64 Bn | - | -55.45% |
| 5 | BeOne Medicines | 39.27 Bn | 34.17 Bn | 1.53 Bn | 13.68% |
| 6 | MindWalk Holdings | 35.32 Bn | 35.31 Bn | 1.82 Bn | -0.20% |
| 7 | Royalty Pharma | 33.72 Bn | 35.84 Bn | - | 7.88% |
| 8 | Alnylam Pharmaceuticals | 30.58 Bn | 27.27 Bn | 992.69 Mn | 26.09% |
| 9 | Insmed | 27.01 Bn | 25.85 Bn | 358.27 Mn | -50.93% |
| 10 | Sionna Therapeutics | 291.76 Mn | 291.76 Mn | - | -38.64% |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | -38.64% |
| Mar 31, 2026 | -32.36% |
| Dec 31, 2025 | -27.73% |
| Sep 30, 2025 | -24.87% |
| Jun 30, 2025 | -24.82% |
| Mar 31, 2025 | -28.74% |