Sionna Therapeutics (SION) Operating Income (2024 - 2026)
Quarterly results put Operating Income at -$29.6 million for Q1 2026, down 50.56% from a year ago — trailing twelve months through Mar 2026 was -$98.9 million (down 28.36% YoY), and the annual figure for FY2025 was -$89.0 million, down 26.12%.
Sionna Therapeutics has reported Operating Income over the past 3 years, most recently at -$29.6 million for Q1 2026.
- Operating Income reached -$29.6 million in Q1 2026 per SION's latest filing, down from -$23.6 million in the prior quarter.
- Across five years, Operating Income topped out at -$11.3 million in Q2 2024 and bottomed at -$29.6 million in Q1 2026.
- Median Operating Income over the past 3 years was -$21.9 million (2025), compared with a mean of -$21.0 million.
- Peak annual rise in Operating Income hit 14.93% in 2025, while the deepest fall reached 94.0% in 2025.
- Over 3 years, Operating Income stood at -$18.1 million in 2024, then tumbled by 30.22% to -$23.6 million in 2025, then decreased by 25.36% to -$29.6 million in 2026.
- Business Quant data shows Operating Income for SION at -$29.6 million in Q1 2026, -$23.6 million in Q4 2025, and -$23.8 million in Q3 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Op. Inc (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 1,384,976.65 Bn | 1,384,976.64 Bn | - | -2.97 Mn |
| 2 | Alterity Therapeutics | 777,208.84 Bn | 777,208.81 Bn | - | - |
| 3 | Legend Biotech | 2,801.00 Bn | 2,800.10 Bn | 242.10 Mn | -19.70 Mn |
| 4 | Nanobiotix | 2,226.01 Bn | 2,225.95 Bn | - | - |
| 5 | Akari Therapeutics | 605.66 Bn | 605.66 Bn | - | -15.76 Mn |
| 6 | Vertex Pharmaceuticals | 110.17 Bn | 102.92 Bn | 2.59 Bn | 1.14 Bn |
| 7 | Regeneron Pharmaceuticals | 66.86 Bn | 58.11 Bn | 3.31 Bn | 642.90 Mn |
| 8 | Evaxion A | 65.12 Bn | 65.10 Bn | - | -3.82 Mn |
| 9 | Alnylam Pharmaceuticals | 39.94 Bn | 36.94 Bn | 959.66 Mn | 268.64 Mn |
| 10 | Sionna Therapeutics | 1.87 Bn | 1.87 Bn | - | -29.60 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -29.60 Mn |
| Dec 31, 2025 | -23.61 Mn |
| Sep 30, 2025 | -23.81 Mn |
| Jun 30, 2025 | -21.91 Mn |
| Mar 31, 2025 | -19.66 Mn |
| Dec 31, 2024 | -18.13 Mn |
| Sep 30, 2024 | -27.98 Mn |
| Jun 30, 2024 | -11.29 Mn |
| Mar 31, 2024 | -13.15 Mn |