Sionna Therapeutics (SION) Operating Income (2024 - 2026)
Sionna Therapeutics (SION) reported Operating Income of -$29.6 million for Q1 2026, down 50.56% on a YoY basis from -$59.9 million in Q1 2025, and down 25.36% sequentially from -$23.6 million in Q4 2025.
Sionna Therapeutics (SION) Operating Income (2024 - 2026) Analysis & Trends
Sionna Therapeutics (SION) has 3 years of Operating Income data on file, last reported at -$29.6 million in Q1 2026.
- For the quarter ending Q1 2026, Operating Income fell 50.56% year-over-year to -$29.6 million; the trailing twelve-month figure through Mar 2026 stood at -$98.9 million (down 28.36% YoY), and the FY2025 full-year result was -$89.0 million, down 26.12% from the prior year.
- Operating Income fell to -$29.6 million in Q1 2026, from -$23.6 million in the prior quarter.
- In the past five years, Operating Income ranged from a high of -$11.3 million in Q2 2024 to a low of -$29.6 million in Q1 2026.
- A 3-year average of -$21.0 million and a median of -$21.9 million in 2025 frame the typical range for Operating Income.
- Peak annual rise in Operating Income reached 14.93% in 2025, while the deepest fall reached 94.0% in 2025.
- Tracing SION's Operating Income over 3 years: stood at -$18.1 million in 2024, then slumped by 30.22% to -$23.6 million in 2025, then dropped by 25.36% to -$29.6 million in 2026.
- Business Quant data shows SION's Operating Income at -$29.6 million in Q1 2026, -$23.6 million in Q4 2025, and -$23.8 million in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Op. Inc (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 67,072.09 Bn | 67,072.09 Bn | - | -27.75 Mn |
| 2 | Nanobiotix | 1,894.61 Bn | 1,894.55 Bn | - | - |
| 3 | Akari Therapeutics | 1,014.18 Bn | 1,014.18 Bn | - | -15.76 Mn |
| 4 | BeOne Medicines | 471.64 Bn | 466.85 Bn | 1.35 Bn | 249.90 Mn |
| 5 | Vertex Pharmaceuticals | 121.72 Bn | 114.47 Bn | 2.59 Bn | 1.14 Bn |
| 6 | Regeneron Pharmaceuticals | 68.28 Bn | 59.52 Bn | 3.31 Bn | 642.90 Mn |
| 7 | Belite Bio | 61.40 Bn | 61.40 Bn | - | -32.68 Mn |
| 8 | Argenx Se | 56.94 Bn | 56.94 Bn | 1.18 Bn | 394.00 Mn |
| 9 | Revolution Medicines | 37.37 Bn | 37.37 Bn | - | -445.22 Mn |
| 10 | Sionna Therapeutics | 2.04 Bn | 2.04 Bn | - | -29.60 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -29.60 Mn |
| Dec 31, 2025 | -23.61 Mn |
| Sep 30, 2025 | -23.81 Mn |
| Jun 30, 2025 | -21.91 Mn |
| Mar 31, 2025 | -19.66 Mn |
| Dec 31, 2024 | -18.13 Mn |
| Sep 30, 2024 | -27.98 Mn |
| Jun 30, 2024 | -11.29 Mn |
| Mar 31, 2024 | -13.15 Mn |