Sionna Therapeutics (SION) Enterprise Value (2024 - 2026)

Sionna Therapeutics (SION) reported Enterprise Value of -$216.2 million for Q1 2026, up 19.85% on a YoY basis from -$180.4 million in Q1 2025, and up 8.37% sequentially from -$235.9 million in Q4 2025.

Sionna Therapeutics (SION) Enterprise Value (2024 - 2026) Analysis & Trends

Sionna Therapeutics (SION) has 3 years of Enterprise Value data on file, last reported at -$216.2 million in Q1 2026.

  • For the quarter ending Q1 2026, Enterprise Value rose 19.85% year-over-year to -$216.2 million; the trailing twelve-month figure through Mar 2026 stood at -$216.2 million (up 19.85% YoY), and the FY2025 full-year result was -$235.9 million, down 59.88% from the prior year.
  • Enterprise Value grew to -$216.2 million in Q1 2026, from -$235.9 million in the prior quarter.
  • In the past five years, Enterprise Value ranged from a high of -$35.7 million in Q3 2024 to a low of -$269.7 million in Q1 2025.
  • A 3-year average of -$171.4 million and a median of -$216.2 million in 2026 frame the typical range for Enterprise Value.
  • Across the five-year window, Enterprise Value plunged 594.65% in 2025 and gained 19.85% in 2026, its largest moves.
  • Tracing SION's Enterprise Value over 3 years: stood at -$147.5 million in 2024, then plunged by 59.88% to -$235.9 million in 2025, then advanced by 8.37% to -$216.2 million in 2026.
  • Business Quant data shows SION's Enterprise Value at -$216.2 million in Q1 2026, -$235.9 million in Q4 2025, and -$248.3 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -283.54 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -61.40 Mn
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn -4.79 Bn
4 NuCana 279.75 Bn 279.75 Bn - -32.26 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn -7.25 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn -8.75 Bn
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -5.18 Bn
9 Revolution Medicines 37.78 Bn 37.78 Bn - -1.91 Bn
10 Sionna Therapeutics 1.98 Bn 1.98 Bn - -216.15 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -216.15 Mn
Dec 31, 2025 -235.88 Mn
Sep 30, 2025 -248.33 Mn
Jun 30, 2025 -262.57 Mn
Mar 31, 2025 -269.67 Mn
Dec 31, 2024 -147.54 Mn
Sep 30, 2024 -35.75 Mn
Jun 30, 2024 -44.02 Mn
Mar 31, 2024 -82.75 Mn