Sionna Therapeutics (SION) Enterprise Value (2024 - 2026)

Sionna Therapeutics' (SION) quarterly Enterprise Value came in at -$216.2 million in Q1 2026, up 19.85% year-on-year from -$180.4 million in Q1 2025, and up 8.37% quarter-over-quarter from -$235.9 million in Q4 2025.

Sionna Therapeutics (SION) Enterprise Value (2024 - 2026) Analysis & Trends

Sionna Therapeutics has disclosed Enterprise Value across 3 years of filings, most recently posting -$216.2 million for Q1 2026.

  • Enterprise Value for Q1 2026 came in at -$216.2 million, up 19.85% year-over-year; the trailing twelve-month figure through Mar 2026 was -$216.2 million (up 19.85% YoY), and the FY2025 annual result was -$235.9 million, down 59.88% from the prior year.
  • Enterprise Value came in at -$216.2 million for Q1 2026 at Sionna Therapeutics, up from -$235.9 million in the prior quarter.
  • In the past five years, Enterprise Value ranged from a high of -$35.7 million in Q3 2024 to a low of -$269.7 million in Q1 2025.
  • The 3-year median for Enterprise Value is -$216.2 million (2026), against an average of -$171.4 million.
  • Across the five-year window, Enterprise Value slumped 594.65% in 2025 and gained 19.85% in 2026, its largest moves.
  • Sionna Therapeutics' Enterprise Value stood at -$147.5 million in 2024, then tumbled by 59.88% to -$235.9 million in 2025, then climbed by 8.37% to -$216.2 million in 2026.
  • The last three Enterprise Value figures came in at -$216.2 million (Q1 2026), -$235.9 million (Q4 2025), and -$248.3 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Alterity Therapeutics 814,307.08 Bn 814,307.05 Bn - -32.30 Mn
2 Belite Bio 55,320.00 Bn 55,320.00 Bn - -
3 Quantum Biopharma 17,149.72 Bn 17,149.72 Bn - -4.14 Mn
4 Legend Biotech 3,590.00 Bn 3,589.71 Bn 242.10 Mn -286.70 Mn
5 Akari Therapeutics 1,650.72 Bn 1,650.72 Bn - -2.77 Mn
6 Evaxion A 1,522.09 Bn 1,522.07 Bn - -18.44 Mn
7 Psyence Biomedical 229.39 Bn 229.38 Bn - -7.20 Mn
8 Vertex Pharmaceuticals 113.09 Bn 105.85 Bn 2.59 Bn -7.25 Bn
9 Abivax 90.15 Bn 90.15 Bn - -584.73 Mn
10 Sionna Therapeutics 1.61 Bn 1.61 Bn - -216.15 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -216.15 Mn
Dec 31, 2025 -235.88 Mn
Sep 30, 2025 -248.33 Mn
Jun 30, 2025 -262.57 Mn
Mar 31, 2025 -269.67 Mn
Dec 31, 2024 -147.54 Mn
Sep 30, 2024 -35.75 Mn
Jun 30, 2024 -44.02 Mn
Mar 31, 2024 -82.75 Mn