Sionna Therapeutics (SION) Enterprise Value (2024 - 2026)
Sionna Therapeutics (SION) posted Enterprise Value of -$216.2 million for Q1 2026, up 8.37% sequentially from -$235.9 million in Q4 2025, and up 19.85% YoY from -$180.4 million in Q1 2025.
Sionna Therapeutics (SION) Enterprise Value (2024 - 2026) Analysis & Trends
Sionna Therapeutics has reported Enterprise Value for 3 years, with the latest figure at -$216.2 million in Q1 2026.
- Quarterly Enterprise Value rose 19.85% year-over-year to -$216.2 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$216.2 million (up 19.85% YoY) and the FY2025 annual result came in at -$235.9 million, down 59.88% from the prior year.
- Enterprise Value grew to -$216.2 million in Q1 2026 per SION's latest filing, from -$235.9 million in the prior quarter.
- Over five years, Enterprise Value peaked at -$35.7 million in Q3 2024 and troughed at -$269.7 million in Q1 2025.
- A 3-year average of -$171.4 million and a median of -$216.2 million in 2026 frame the typical range for Enterprise Value.
- The sharpest annual moves came in 2025 and 2026: Enterprise Value slumped 594.65% in 2025, then climbed 19.85% in 2026.
- Over 3 years, Enterprise Value stood at -$147.5 million in 2024, then tumbled by 59.88% to -$235.9 million in 2025, then increased by 8.37% to -$216.2 million in 2026.
- According to Business Quant data, Enterprise Value over the past three periods registered -$216.2 million, -$235.9 million, and -$248.3 million for Q1 2026, Q4 2025, and Q3 2025 respectively.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Enterprise Value (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 128.13 Bn | 120.28 Bn | 2.84 Bn | -7.85 Bn |
| 2 | Regeneron Pharmaceuticals | 112.33 Bn | 104.33 Bn | 3.93 Bn | -7.99 Bn |
| 3 | Argenx Se | 53.24 Bn | 48.05 Bn | 1.41 Bn | -5.18 Bn |
| 4 | Revolution Medicines | 43.64 Bn | 43.64 Bn | - | -3.94 Bn |
| 5 | BeOne Medicines | 39.27 Bn | 34.17 Bn | 1.53 Bn | -5.10 Bn |
| 6 | MindWalk Holdings | 35.32 Bn | 35.31 Bn | 1.82 Bn | -8.46 Mn |
| 7 | Royalty Pharma | 33.72 Bn | 35.84 Bn | - | 2.12 Bn |
| 8 | Alnylam Pharmaceuticals | 30.58 Bn | 27.27 Bn | 992.69 Mn | -3.31 Bn |
| 9 | Insmed | 27.01 Bn | 25.85 Bn | 358.27 Mn | -1.16 Bn |
| 10 | Sionna Therapeutics | 291.76 Mn | 291.76 Mn | - | -211.03 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | -211.03 Mn |
| Mar 31, 2026 | -216.15 Mn |
| Dec 31, 2025 | -235.88 Mn |
| Sep 30, 2025 | -248.33 Mn |
| Jun 30, 2025 | -262.57 Mn |
| Mar 31, 2025 | -269.67 Mn |
| Dec 31, 2024 | -147.54 Mn |
| Sep 30, 2024 | -35.75 Mn |
| Jun 30, 2024 | -44.02 Mn |
| Mar 31, 2024 | -82.75 Mn |