Sionna Therapeutics (SION) EBT (2024 - 2026)
Sionna Therapeutics (SION) reported EBT of -$26.8 million for Q1 2026, down 60.75% on a YoY basis from -$68.2 million in Q1 2025, and up 85.79% sequentially from -$188.4 million in Q4 2025.
Sionna Therapeutics (SION) EBT (2024 - 2026) Analysis & Trends
Sionna Therapeutics (SION) has 3 years of EBT data on file, last reported at -$26.8 million in Q1 2026.
- For the quarter ending Q1 2026, EBT fell 60.75% year-over-year to -$26.8 million; the trailing twelve-month figure through Mar 2026 stood at -$253.8 million (down 113.94% YoY), and the FY2025 full-year result was -$243.7 million, down 113.78% from the prior year.
- EBT advanced to -$26.8 million in Q1 2026, from -$188.4 million in the prior quarter.
- In the past five years, EBT ranged from a high of -$8.7 million in Q2 2024 to a low of -$188.4 million in Q4 2025.
- A 3-year average of -$42.7 million and a median of -$20.3 million in 2025 frame the typical range for EBT.
- Peak annual rise in EBT reached 20.61% in 2025, while the deepest fall reached 178.69% in 2025.
- Tracing SION's EBT over 3 years: stood at -$67.6 million in 2024, then slumped by 178.69% to -$188.4 million in 2025, then surged by 85.79% to -$26.8 million in 2026.
- Business Quant data shows SION's EBT at -$26.8 million in Q1 2026, -$188.4 million in Q4 2025, and -$20.3 million in Q3 2025.
Powered by 
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBT (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | -36.97 Mn |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 259.22 Mn |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | -3.49 Mn |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 1.25 Bn |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 831.20 Mn |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | -26.94 Mn |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | 541.00 Mn |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | -453.82 Mn |
| 10 | Sionna Therapeutics | 1.98 Bn | 1.98 Bn | - | -26.78 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -26.78 Mn |
| Dec 31, 2025 | -188.45 Mn |
| Sep 30, 2025 | -20.35 Mn |
| Jun 30, 2025 | -18.24 Mn |
| Mar 31, 2025 | -16.66 Mn |
| Dec 31, 2024 | -67.62 Mn |
| Sep 30, 2024 | -25.63 Mn |
| Jun 30, 2024 | -8.73 Mn |
| Mar 31, 2024 | -12.02 Mn |