Sionna Therapeutics (SION) EBT (2024 - 2026)
Sionna Therapeutics (SION) posted EBT of -$26.8 million for Q1 2026, up 85.79% sequentially from -$188.4 million in Q4 2025, and down 60.75% YoY from -$68.2 million in Q1 2025.
Sionna Therapeutics (SION) EBT (2024 - 2026) Analysis & Trends
Sionna Therapeutics has reported EBT for 3 years, with the latest figure at -$26.8 million in Q1 2026.
- Quarterly EBT fell 60.75% year-over-year to -$26.8 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$253.8 million (down 113.94% YoY) and the FY2025 annual result came in at -$243.7 million, down 113.78% from the prior year.
- EBT advanced to -$26.8 million in Q1 2026 per SION's latest filing, from -$188.4 million in the prior quarter.
- Over five years, EBT peaked at -$8.7 million in Q2 2024 and troughed at -$188.4 million in Q4 2025.
- A 3-year average of -$42.7 million and a median of -$20.3 million in 2025 frame the typical range for EBT.
- The widest YoY moves for EBT: up 20.61% in 2025, down 178.69% in 2025.
- Over 3 years, EBT stood at -$67.6 million in 2024, then sank by 178.69% to -$188.4 million in 2025, then surged by 85.79% to -$26.8 million in 2026.
- According to Business Quant data, EBT over the past three periods registered -$26.8 million, -$188.4 million, and -$20.3 million for Q1 2026, Q4 2025, and Q3 2025 respectively.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBT (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 128.13 Bn | 120.28 Bn | 2.84 Bn | 1.39 Bn |
| 2 | Regeneron Pharmaceuticals | 112.33 Bn | 104.33 Bn | 3.93 Bn | 1.53 Bn |
| 3 | Argenx Se | 53.24 Bn | 48.05 Bn | 1.41 Bn | 541.00 Mn |
| 4 | Revolution Medicines | 43.64 Bn | 43.64 Bn | - | -644.37 Mn |
| 5 | BeOne Medicines | 39.27 Bn | 34.17 Bn | 1.53 Bn | 312.46 Mn |
| 6 | MindWalk Holdings | 35.32 Bn | 35.31 Bn | 1.82 Bn | -2,828.29 |
| 7 | Royalty Pharma | 33.72 Bn | 35.84 Bn | - | 81.49 Mn |
| 8 | Alnylam Pharmaceuticals | 30.58 Bn | 27.27 Bn | 992.69 Mn | 177.81 Mn |
| 9 | Insmed | 27.01 Bn | 25.85 Bn | 358.27 Mn | -11.37 Mn |
| 10 | Sionna Therapeutics | 291.76 Mn | 291.76 Mn | - | -29.88 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | -29.88 Mn |
| Mar 31, 2026 | -26.78 Mn |
| Dec 31, 2025 | -188.45 Mn |
| Sep 30, 2025 | -20.35 Mn |
| Jun 30, 2025 | -18.24 Mn |
| Mar 31, 2025 | -16.66 Mn |
| Dec 31, 2024 | -67.62 Mn |
| Sep 30, 2024 | -25.63 Mn |
| Jun 30, 2024 | -8.73 Mn |
| Mar 31, 2024 | -12.02 Mn |