Sionna Therapeutics (SION) EBITDA (2024 - 2026)
Sionna Therapeutics' (SION) quarterly EBITDA came in at -$27.4 million in Q1 2026, down 65.59% year-on-year from -$79.6 million in Q1 2025, and down 34.86% quarter-over-quarter from -$20.3 million in Q4 2025.
Sionna Therapeutics (SION) EBITDA (2024 - 2026) Analysis & Trends
Sionna Therapeutics has disclosed EBITDA across 3 years of filings, most recently posting -$27.4 million for Q1 2026.
- EBITDA for Q1 2026 came in at -$27.4 million, down 65.59% year-over-year; the trailing twelve-month figure through Mar 2026 was -$86.0 million (down 30.2% YoY), and the FY2025 annual result was -$75.1 million, down 22.47% from the prior year.
- EBITDA came in at -$27.4 million for Q1 2026 at Sionna Therapeutics, down from -$20.3 million in the prior quarter.
- In the past five years, EBITDA ranged from a high of -$8.7 million in Q2 2024 to a low of -$27.4 million in Q1 2026.
- The 3-year median for EBITDA is -$18.2 million (2025), against an average of -$18.2 million.
- Peak annual rise in EBITDA reached 18.24% in 2025, while the deepest fall reached 109.03% in 2025.
- Sionna Therapeutics' EBITDA stood at -$16.3 million in 2024, then retreated by 25.02% to -$20.3 million in 2025, then tumbled by 34.86% to -$27.4 million in 2026.
- The last three EBITDA figures came in at -$27.4 million (Q1 2026), -$20.3 million (Q4 2025), and -$20.0 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 814,307.08 Bn | 814,307.05 Bn | - | - |
| 2 | Belite Bio | 55,320.00 Bn | 55,320.00 Bn | - | -26.92 Mn |
| 3 | Quantum Biopharma | 17,149.72 Bn | 17,149.72 Bn | - | -13.63 Mn |
| 4 | Legend Biotech | 3,590.00 Bn | 3,589.71 Bn | 242.10 Mn | -19.70 Mn |
| 5 | Akari Therapeutics | 1,650.72 Bn | 1,650.72 Bn | - | -14.44 Mn |
| 6 | Evaxion A | 1,522.09 Bn | 1,522.07 Bn | - | -3.82 Mn |
| 7 | Psyence Biomedical | 229.39 Bn | 229.38 Bn | - | -752,618.00 |
| 8 | Vertex Pharmaceuticals | 113.09 Bn | 105.85 Bn | 2.59 Bn | 1.14 Bn |
| 9 | Abivax | 90.15 Bn | 90.15 Bn | - | -65.83 Mn |
| 10 | Sionna Therapeutics | 1.61 Bn | 1.61 Bn | - | -27.40 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -27.40 Mn |
| Dec 31, 2025 | -20.32 Mn |
| Sep 30, 2025 | -20.04 Mn |
| Jun 30, 2025 | -18.19 Mn |
| Mar 31, 2025 | -16.55 Mn |
| Dec 31, 2024 | -16.25 Mn |
| Sep 30, 2024 | -24.51 Mn |
| Jun 30, 2024 | -8.70 Mn |
| Mar 31, 2024 | -11.86 Mn |