Sionna Therapeutics (SION) EBITDA (2024 - 2026)
Quarterly results put EBITDA at -$27.4 million for Q1 2026, down 65.59% from a year ago — trailing twelve months through Mar 2026 was -$86.0 million (down 30.2% YoY), and the annual figure for FY2025 was -$75.1 million, down 22.47%.
Sionna Therapeutics has reported EBITDA over the past 3 years, most recently at -$27.4 million for Q1 2026.
- EBITDA reached -$27.4 million in Q1 2026 per SION's latest filing, down from -$20.3 million in the prior quarter.
- Across five years, EBITDA topped out at -$8.7 million in Q2 2024 and bottomed at -$27.4 million in Q1 2026.
- Median EBITDA over the past 3 years was -$18.2 million (2025), compared with a mean of -$18.2 million.
- Peak annual rise in EBITDA hit 18.24% in 2025, while the deepest fall reached 109.03% in 2025.
- Over 3 years, EBITDA stood at -$16.3 million in 2024, then dropped by 25.02% to -$20.3 million in 2025, then crashed by 34.86% to -$27.4 million in 2026.
- Business Quant data shows EBITDA for SION at -$27.4 million in Q1 2026, -$20.3 million in Q4 2025, and -$20.0 million in Q3 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 1,384,976.65 Bn | 1,384,976.64 Bn | - | -13.63 Mn |
| 2 | Alterity Therapeutics | 777,208.84 Bn | 777,208.81 Bn | - | - |
| 3 | Legend Biotech | 2,801.00 Bn | 2,800.10 Bn | 242.10 Mn | -19.70 Mn |
| 4 | Nanobiotix | 2,226.01 Bn | 2,225.95 Bn | - | - |
| 5 | Akari Therapeutics | 605.66 Bn | 605.66 Bn | - | -14.44 Mn |
| 6 | Vertex Pharmaceuticals | 110.17 Bn | 102.92 Bn | 2.59 Bn | 1.14 Bn |
| 7 | Regeneron Pharmaceuticals | 66.86 Bn | 58.11 Bn | 3.31 Bn | 661.60 Mn |
| 8 | Evaxion A | 65.12 Bn | 65.10 Bn | - | -3.82 Mn |
| 9 | Alnylam Pharmaceuticals | 39.94 Bn | 36.94 Bn | 959.66 Mn | 201.19 Mn |
| 10 | Sionna Therapeutics | 1.87 Bn | 1.87 Bn | - | -27.40 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -27.40 Mn |
| Dec 31, 2025 | -20.32 Mn |
| Sep 30, 2025 | -20.04 Mn |
| Jun 30, 2025 | -18.19 Mn |
| Mar 31, 2025 | -16.55 Mn |
| Dec 31, 2024 | -16.25 Mn |
| Sep 30, 2024 | -24.51 Mn |
| Jun 30, 2024 | -8.70 Mn |
| Mar 31, 2024 | -11.86 Mn |