Septerna (SEPN) Return on Capital Employed (2024 - 2026)

Septerna's Return on Capital Employed history runs 3 years deep, the most recent figure standing at 0.47% for Q1 2026.

• In Q1 2026, Return on Capital Employed rose 2146.0% year-over-year to 0.47%; the TTM figure through Mar 2026 stood at 0.47% (up 2146.0% YoY), while the FY2025 annual figure was 2.34%, up 2644.0% from the prior year.
• Return on Capital Employed was 0.47% for Q1 2026 at Septerna, up from 1.99% in the prior quarter.
• In the past five years, Return on Capital Employed ranged from a high of 0.47% in Q1 2026 to a low of 26.71% in Q4 2024.
• Historically, Return on Capital Employed has averaged 15.31% across 3 years, with a median of 19.33% in 2025.
• The sharpest annual moves came in 2025 and 2026: Return on Capital Employed jumped 2472 bps in 2025, then soared 2146 bps in 2026.
• A 3-year view of Return on Capital Employed shows it stood at 26.71% in 2024, then surged by 93 bps to 1.99% in 2025, then surged by 123 bps to 0.47% in 2026.
• The last three Return on Capital Employed figures came in at 0.47% (Q1 2026), 1.99% (Q4 2025), and 17.67% (Q3 2025), per Business Quant data.