Septerna (SEPN) Retained Earnings (2023 - 2026)

Septerna's quarterly Retained Earnings came in at -$569000.0 in Q1 2026, up 99.59% year-on-year from -$285079.9 in Q1 2025, and up 99.66% quarter-over-quarter from -$167.3 million in Q4 2025.

Septerna has reported Retained Earnings for 4 years, with the latest figure at -$569000.0 in Q1 2026.

  • For the quarter ending Q1 2026, Retained Earnings rose 99.59% year-over-year to -$569000.0; the trailing twelve-month figure through Mar 2026 stood at -$569000.0 (up 99.59% YoY), and the FY2025 full-year result was -$167.3 million, down 41.29% from the prior year.
  • Retained Earnings for Q1 2026 stood at -$569000.0, up from -$167.3 million in the prior quarter.
  • The five-year high for Retained Earnings was $375000.0 in Q3 2025, with the low at -$167.3 million in Q4 2025.
  • Average Retained Earnings over 4 years is -$91.8 million, with a median of -$108.0 million recorded in 2024.
  • Year-over-year, Retained Earnings slumped 154.15% in 2024 and soared 100.38% in 2025.
  • Tracing SEPN's Retained Earnings over 4 years: stood at -$46.6 million in 2023, then tumbled by 154.15% to -$118.4 million in 2024, then sank by 41.29% to -$167.3 million in 2025, then jumped by 99.66% to -$569000.0 in 2026.
  • The last three Retained Earnings figures came in at -$569000.0 (Q1 2026), -$167.3 million (Q4 2025), and $375000.0 (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Retained Earnings (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -211.85 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -153.89 Mn
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn 1.00 Bn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -438.66 Mn
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -279.00 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 14.59 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - 130.89 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 36.42 Bn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn -24.89 Mn
10 Septerna 1.34 Bn 1.34 Bn - -569,000.00

Historic Data

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DateValue
Mar 31, 2026 -569,000.00
Dec 31, 2025 -167.25 Mn
Sep 30, 2025 375,000.00
Jun 30, 2025 -164.69 Mn
Mar 31, 2025 -139.85 Mn
Dec 31, 2024 -118.37 Mn
Sep 30, 2024 -97.70 Mn
Dec 31, 2023 -46.58 Mn