Septerna (SEPN) Retained Earnings (2023 - 2026)

Septerna's (SEPN) quarterly Retained Earnings came in at -$175.9 million in Q1 2026, down 88933.33% year-on-year from N/an in Q1 2025, and down 28607.29% quarter-over-quarter from $617000.0 in Q4 2025.

Septerna (SEPN) Retained Earnings (2023 - 2026) Analysis & Trends

Septerna's Retained Earnings history runs 4 years deep, the most recent figure standing at -$175.9 million for Q1 2026.

  • On a quarterly basis, Retained Earnings fell 88933.33% year-over-year to -$175.9 million in Q1 2026; TTM through Mar 2026 was -$175.9 million, a 88933.33% decrease from a year earlier, with the FY2025 full-year figure at $617000.0, up 1001.79% from the prior year.
  • Retained Earnings slipped to -$175.9 million in Q1 2026 per SEPN's latest filing, from $617000.0 in the prior quarter.
  • Across five years, Retained Earnings topped out at $617000.0 in Q4 2025 and bottomed at -$175.9 million in Q1 2026.
  • The 4-year median for Retained Earnings is -$23.3 million (2023), against an average of -$67.8 million.
  • Biggest YoY gain for Retained Earnings was 1001.79% in 2025; the steepest drop was 89028.98% in 2025.
  • Year by year, Retained Earnings stood at -$46.6 million in 2023, then jumped by 100.12% to $56000.0 in 2024, then soared by 1001.79% to $617000.0 in 2025, then sank by 28607.29% to -$175.9 million in 2026.
  • Per Business Quant, the three latest SEPN Retained Earnings figures stand at -$175.9 million (Q1 2026), $617000.0 (Q4 2025), and -$156.5 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Retained Earnings (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -527.87 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -27.89 Mn
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 12.91 Bn
4 NuCana 279.75 Bn 279.75 Bn - 115.82 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 14.59 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 11.90 Mn
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 1.41 Bn
9 Revolution Medicines 37.78 Bn 37.78 Bn - -622,000.00
10 Septerna 1.50 Bn 1.50 Bn - -175.89 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -175.89 Mn
Dec 31, 2025 617,000.00
Sep 30, 2025 -156.52 Mn
Jun 30, 2025 -164.70 Mn
Mar 31, 2025 198,000.00
Dec 31, 2024 56,000.00
Sep 30, 2024 176,000.00
Dec 31, 2023 -46.58 Mn