Septerna (SEPN) Profit After Tax (2023 - 2026)

Septerna (SEPN) recorded quarterly Profit After Tax of -$8.6 million in Q1 2026, up 20.03% quarter-over-quarter from -$10.8 million in Q4 2025, and up 59.78% on a YoY basis from -$5.4 million in Q1 2025.

Septerna (SEPN) Profit After Tax (2023 - 2026) Analysis & Trends

Septerna's Profit After Tax history runs 4 years deep, the most recent figure standing at -$8.6 million for Q1 2026.

  • In Q1 2026, Profit After Tax rose 59.78% year-over-year to -$8.6 million; the TTM figure through Mar 2026 stood at -$36.1 million (up 54.4% YoY), while the FY2025 annual figure was -$48.9 million, up 31.89% from the prior year.
  • Profit After Tax was -$8.6 million for Q1 2026 at Septerna, up from -$10.8 million in the prior quarter.
  • In the past five years, Profit After Tax ranged from a high of $34.9 million in Q4 2023 to a low of -$24.8 million in Q2 2025.
  • Historically, Profit After Tax has averaged -$9.6 million across 4 years, with a median of -$14.1 million in 2024.
  • The sharpest annual moves came in 2024 and 2025: Profit After Tax slumped 159.23% in 2024, then soared 139.82% in 2025.
  • A 4-year view of Profit After Tax shows it stood at $34.9 million in 2023, then slumped by 159.23% to -$20.7 million in 2024, then surged by 47.75% to -$10.8 million in 2025, then grew by 20.03% to -$8.6 million in 2026.
  • The last three Profit After Tax figures came in at -$8.6 million (Q1 2026), -$10.8 million (Q4 2025), and $8.2 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) PAT (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -26.94 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -2.97 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 30.90 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -3.63 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -14.46 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -753,254.00
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.03 Bn
9 Abivax 91.96 Bn 91.96 Bn - -56.74 Mn
10 Septerna 1.62 Bn 1.62 Bn - -8.64 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -8.64 Mn
Dec 31, 2025 -10.80 Mn
Sep 30, 2025 8.17 Mn
Jun 30, 2025 -24.84 Mn
Mar 31, 2025 -21.48 Mn
Dec 31, 2024 -20.67 Mn
Sep 30, 2024 -20.52 Mn
Jun 30, 2024 -16.51 Mn
Mar 31, 2024 -14.10 Mn
Dec 31, 2023 34.89 Mn
Sep 30, 2023 -10.95 Mn