Septerna (SEPN) Profit After Tax (2023 - 2026)

Septerna (SEPN) posted quarterly Profit After Tax of -$1.2 million for Q1 2026, up 94.48% year-over-year from -$609839.0 in Q1 2025, and up 97.59% quarter-over-quarter from -$49.2 million in Q4 2025.

Septerna (SEPN) Profit After Tax (2023 - 2026) Analysis & Trends

Septerna's Profit After Tax history runs 4 years deep, the most recent figure standing at -$1.2 million for Q1 2026.

  • In Q1 2026, Profit After Tax rose 94.48% year-over-year to -$1.2 million; the TTM figure through Mar 2026 stood at -$66.9 million (up 15.73% YoY), while the FY2025 annual figure was -$48.9 million, up 31.89% from the prior year.
  • Profit After Tax for Q1 2026 stood at -$1.2 million, up from -$49.2 million in the prior quarter.
  • The five-year high for Profit After Tax was $34.9 million in Q4 2023, with the low at -$49.2 million in Q4 2025.
  • The 4-year median for Profit After Tax is -$16.5 million (2024), against an average of -$12.4 million.
  • The sharpest annual moves came in 2024 and 2025: Profit After Tax slumped 159.74% in 2024, then soared 140.79% in 2025.
  • Septerna's Profit After Tax stood at $34.9 million in 2023, then plunged by 159.74% to -$20.8 million in 2024, then tumbled by 136.13% to -$49.2 million in 2025, then soared by 97.59% to -$1.2 million in 2026.
  • Business Quant data shows SEPN's Profit After Tax at -$1.2 million in Q1 2026, -$49.2 million in Q4 2025, and $8.4 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) PAT (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 1.10 Bn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 1.30 Bn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 472.00 Mn
4 Revolution Medicines 43.64 Bn 43.64 Bn - -644.37 Mn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 237.01 Mn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -3,087.27
7 Royalty Pharma 33.72 Bn 35.84 Bn - 81.49 Mn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 164.49 Mn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -16.62 Mn
10 Septerna 2.08 Bn 2.08 Bn - -13.73 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 -13.73 Mn
Mar 31, 2026 -1.19 Mn
Dec 31, 2025 -49.22 Mn
Sep 30, 2025 8.37 Mn
Jun 30, 2025 -24.84 Mn
Mar 31, 2025 -21.48 Mn
Dec 31, 2024 -20.84 Mn
Sep 30, 2024 -20.52 Mn
Jun 30, 2024 -16.51 Mn
Mar 31, 2024 -14.10 Mn
Dec 31, 2023 34.89 Mn
Sep 30, 2023 -10.95 Mn