Septerna (SEPN) Profit After Tax (2023 - 2026)

Septerna's (SEPN) quarterly Profit After Tax came in at -$1.2 million in Q1 2026, up 94.48% year-on-year from -$609839.0 in Q1 2025, and up 97.59% quarter-over-quarter from -$49.2 million in Q4 2025.

Septerna (SEPN) Profit After Tax (2023 - 2026) Analysis & Trends

Septerna's Profit After Tax history runs 4 years deep, the most recent figure standing at -$1.2 million for Q1 2026.

  • On a quarterly basis, Profit After Tax rose 94.48% year-over-year to -$1.2 million in Q1 2026; TTM through Mar 2026 was -$66.9 million, a 15.73% increase from a year earlier, with the FY2025 full-year figure at -$48.9 million, up 31.89% from the prior year.
  • Profit After Tax climbed to -$1.2 million in Q1 2026 per SEPN's latest filing, from -$49.2 million in the prior quarter.
  • Across five years, Profit After Tax topped out at $34.9 million in Q4 2023 and bottomed at -$49.2 million in Q4 2025.
  • The 4-year median for Profit After Tax is -$16.5 million (2024), against an average of -$12.4 million.
  • Across the five-year window, Profit After Tax tumbled 159.74% in 2024 and soared 140.79% in 2025, its largest moves.
  • Year by year, Profit After Tax stood at $34.9 million in 2023, then tumbled by 159.74% to -$20.8 million in 2024, then slumped by 136.13% to -$49.2 million in 2025, then jumped by 97.59% to -$1.2 million in 2026.
  • Per Business Quant, the three latest SEPN Profit After Tax figures stand at -$1.2 million (Q1 2026), -$49.2 million (Q4 2025), and $8.4 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) PAT (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -36.84 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 227.36 Mn
4 NuCana 279.75 Bn 279.75 Bn - -
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 1.03 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn -65.60 Mn
7 Belite Bio 62.51 Bn 62.51 Bn - -26.94 Mn
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 362.00 Mn
9 Revolution Medicines 37.78 Bn 37.78 Bn - -453.82 Mn
10 Septerna 1.50 Bn 1.50 Bn - -1.19 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -1.19 Mn
Dec 31, 2025 -49.22 Mn
Sep 30, 2025 8.37 Mn
Jun 30, 2025 -24.84 Mn
Mar 31, 2025 -21.48 Mn
Dec 31, 2024 -20.84 Mn
Sep 30, 2024 -20.52 Mn
Jun 30, 2024 -16.51 Mn
Mar 31, 2024 -14.10 Mn
Dec 31, 2023 34.89 Mn
Sep 30, 2023 -10.95 Mn