Septerna (SEPN) Operating Income (2023 - 2026)
Septerna's Operating Income was -$16.84 million in Q2 2026, compared with -$28.98 million a year earlier.
Powered by 
Analysis
Septerna (SEPN) Operating Income (2023 - 2026) Analysis & Trends
On a trailing twelve-month basis, Septerna's Operating Income was -$43.55 million through Jun 30, 2026; for FY2025, it came in at -$68.3 million.
- In earlier years, Operating Income was -$80.82 million in FY2024 and $2.08 million in FY2023.
- Quarterly Operating Income has moved between -$28.98 million (Q2 2025) and $34.32 million (Q4 2023) over five years.
- Per Business Quant data, SEPN's Operating Income in the three quarters before Q2 2026 was -$13.3 million (Q1 2026), -$16.02 million (Q4 2025) and $2.61 million (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Op. Inc (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,166.05 Bn | 1,134.64 Bn | 19.71 Bn | 11.75 Bn |
| 2 | Johnson & Johnson | 647.70 Bn | 567.56 Bn | 17.30 Bn | 6.18 Bn |
| 3 | AbbVie | 503.26 Bn | 476.37 Bn | 12.70 Bn | 6.43 Bn |
| 4 | Merck | 366.29 Bn | 320.67 Bn | 12.21 Bn | -584.00 Mn |
| 5 | Novartis Ag | 303.09 Bn | 267.08 Bn | 11.24 Bn | 4.75 Bn |
| 6 | Astrazeneca | 268.96 Bn | 242.64 Bn | 12.86 Bn | 3.16 Bn |
| 7 | Amgen | 242.14 Bn | 197.54 Bn | 7.24 Bn | 3.51 Bn |
| 8 | Gilead Sciences | 194.83 Bn | 169.02 Bn | 6.22 Bn | -10.39 Bn |
| 9 | Pfizer | 172.37 Bn | 119.01 Bn | 10.94 Bn | 4.27 Bn |
| 10 | Septerna | 1.84 Bn | 256.98 Mn | - | -16.84 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -16.84 Mn |
| Mar 31, 2026 | -13.30 Mn |
| Dec 31, 2025 | -16.02 Mn |
| Sep 30, 2025 | 2.61 Mn |
| Jun 30, 2025 | -28.98 Mn |
| Mar 31, 2025 | -25.91 Mn |
| Dec 31, 2024 | -24.72 Mn |
| Sep 30, 2024 | -22.55 Mn |
| Jun 30, 2024 | -18.07 Mn |
| Mar 31, 2024 | -15.49 Mn |
| Dec 31, 2023 | 34.32 Mn |
| Sep 30, 2023 | -12.04 Mn |
API Access
Septerna Operating Income API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-income&ticker=SEPN&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-income", "ticker": "SEPN", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=operating-income&ticker=SEPN&period=max&api_key=YOUR_API_KEY");
const data = await res.json();