Septerna (SEPN) EPS (Basic) (2023 - 2026)

Septerna's quarterly EPS (Basic) came in at -$0.19 in Q1 2026, up 61.22% year-on-year from -$0.12 in Q1 2025, and up 20.83% quarter-over-quarter from -$0.24 in Q4 2025.

Septerna has reported EPS (Basic) for 4 years, with the latest figure at -$0.19 in Q1 2026.

  • For the quarter ending Q1 2026, EPS (Basic) rose 61.22% year-over-year to -$0.19; the trailing twelve-month figure through Mar 2026 stood at -$0.81 (up 38.17% YoY), and the FY2025 full-year result was -$1.1, up 84.85% from the prior year.
  • EPS (Basic) for Q1 2026 stood at -$0.19, up from -$0.24 in the prior quarter.
  • The five-year high for EPS (Basic) was $16.78 in Q4 2023, with the low at -$8.4 in Q3 2024.
  • Average EPS (Basic) over 4 years is $0.26, with a median of -$0.49 recorded in 2025.
  • Peak annual rise in EPS (Basic) reached 102.14% in 2025, while the deepest fall reached 101.64% in 2025.
  • Tracing SEPN's EPS (Basic) over 4 years: stood at $16.78 in 2023, then decreased by 12.93% to $14.61 in 2024, then tumbled by 101.64% to -$0.24 in 2025, then gained by 20.83% to -$0.19 in 2026.
  • The last three EPS (Basic) figures came in at -$0.19 (Q1 2026), -$0.24 (Q4 2025), and $0.18 (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EPS (Basic) (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - 3.06
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn 0.00
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - 0.00
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 4.06
7 Evaxion A 62.56 Bn 62.54 Bn - 0.00
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 6.99
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 1.55
10 Septerna 1.34 Bn 1.34 Bn - -0.19

Historic Data

Download Data 🔒
DateValue
Mar 31, 2026 -0.19
Dec 31, 2025 -0.24
Sep 30, 2025 0.18
Jun 30, 2025 -0.56
Mar 31, 2025 -0.49
Dec 31, 2024 14.61
Sep 30, 2024 -8.40
Jun 30, 2024 -7.03
Mar 31, 2024 -6.35
Dec 31, 2023 16.78
Sep 30, 2023 -5.45