Septerna (SEPN) EPS (Basic) (2023 - 2026)

Septerna's (SEPN) quarterly EPS (Basic) came in at -$0.19 in Q1 2026, up 60.52% year-on-year from -$0.12 in Q1 2025, and up 20.47% quarter-over-quarter from -$0.24 in Q4 2025.

Septerna (SEPN) EPS (Basic) (2023 - 2026) Analysis & Trends

Septerna's EPS (Basic) history runs 4 years deep, the most recent figure standing at -$0.19 for Q1 2026.

  • On a quarterly basis, EPS (Basic) rose 60.52% year-over-year to -$0.19 in Q1 2026; TTM through Mar 2026 was -$0.81, a 55.4% increase from a year earlier, with the FY2025 full-year figure at -$1.1, up 84.79% from the prior year.
  • EPS (Basic) rose to -$0.19 in Q1 2026 per SEPN's latest filing, from -$0.24 in the prior quarter.
  • Across five years, EPS (Basic) topped out at $0.18 in Q3 2025 and bottomed at -$9.41 in Q4 2023.
  • The 4-year median for EPS (Basic) is -$2.09 (2024), against an average of -$3.66.
  • Across the five-year window, EPS (Basic) slumped 54.05% in 2024 and surged 102.19% in 2025, its largest moves.
  • Year by year, EPS (Basic) stood at -$9.41 in 2023, then surged by 77.8% to -$2.09 in 2024, then jumped by 88.39% to -$0.24 in 2025, then grew by 20.47% to -$0.19 in 2026.
  • Per Business Quant, the three latest SEPN EPS (Basic) figures stand at -$0.19 (Q1 2026), -$0.24 (Q4 2025), and $0.18 (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EPS (Basic) (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - 0.00
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 0.16
4 NuCana 279.75 Bn 279.75 Bn - 0.00
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 4.06
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 6.99
7 Belite Bio 62.51 Bn 62.51 Bn - 0.00
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 7.59
9 Revolution Medicines 37.78 Bn 37.78 Bn - -2.29
10 Septerna 1.50 Bn 1.50 Bn - -0.19

Historic Data

Download Data
DateValue
Mar 31, 2026 -0.19
Dec 31, 2025 -0.24
Sep 30, 2025 0.18
Jun 30, 2025 -0.56
Mar 31, 2025 -0.49
Dec 31, 2024 -2.09
Sep 30, 2024 -8.40
Jun 30, 2024 -7.13
Mar 31, 2024 -6.43
Dec 31, 2023 -9.41
Sep 30, 2023 -5.45