Septerna (SEPN) EPS (Basic) (2023 - 2026)

Septerna (SEPN) recorded quarterly EPS (Basic) of -$0.19 in Q1 2026, up 20.83% quarter-over-quarter from -$0.24 in Q4 2025, and up 61.22% on a YoY basis from -$0.12 in Q1 2025.

Septerna (SEPN) EPS (Basic) (2023 - 2026) Analysis & Trends

Septerna's EPS (Basic) history runs 4 years deep, the most recent figure standing at -$0.19 for Q1 2026.

  • In Q1 2026, EPS (Basic) rose 61.22% year-over-year to -$0.19; the TTM figure through Mar 2026 stood at -$0.81 (up 38.17% YoY), while the FY2025 annual figure was -$1.1, up 84.85% from the prior year.
  • EPS (Basic) was -$0.19 for Q1 2026 at Septerna, up from -$0.24 in the prior quarter.
  • In the past five years, EPS (Basic) ranged from a high of $16.78 in Q4 2023 to a low of -$8.4 in Q3 2024.
  • Historically, EPS (Basic) has averaged $0.26 across 4 years, with a median of -$0.49 in 2025.
  • Biggest YoY gain for EPS (Basic) was 102.14% in 2025; the steepest drop was 101.64% in 2025.
  • A 4-year view of EPS (Basic) shows it stood at $16.78 in 2023, then retreated by 12.93% to $14.61 in 2024, then plunged by 101.64% to -$0.24 in 2025, then rose by 20.83% to -$0.19 in 2026.
  • The last three EPS (Basic) figures came in at -$0.19 (Q1 2026), -$0.24 (Q4 2025), and $0.18 (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EPS (Basic) (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -0.68
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - 3.06
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 0.00
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - 0.00
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - 0.00
7 Psyence Biomedical 212.16 Bn 212.16 Bn - 0.00
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 4.06
9 Abivax 91.96 Bn 91.96 Bn - -0.06
10 Septerna 1.62 Bn 1.62 Bn - -0.19

Historic Data

Download Data
DateValue
Mar 31, 2026 -0.19
Dec 31, 2025 -0.24
Sep 30, 2025 0.18
Jun 30, 2025 -0.56
Mar 31, 2025 -0.49
Dec 31, 2024 14.61
Sep 30, 2024 -8.40
Jun 30, 2024 -7.03
Mar 31, 2024 -6.35
Dec 31, 2023 16.78
Sep 30, 2023 -5.45