Septerna (SEPN) EBT (2023 - 2026)

Septerna's quarterly EBT came in at -$8.3 million in Q1 2026, up 61.35% year-on-year from -$5.1 million in Q1 2025, and up 22.62% quarter-over-quarter from -$10.7 million in Q4 2025.

Septerna has reported EBT for 4 years, with the latest figure at -$8.3 million in Q1 2026.

  • For the quarter ending Q1 2026, EBT rose 61.35% year-over-year to -$8.3 million; the trailing twelve-month figure through Mar 2026 stood at -$35.7 million (up 55.11% YoY), and the FY2025 full-year result was -$48.9 million, up 32.41% from the prior year.
  • EBT for Q1 2026 stood at -$8.3 million, up from -$10.7 million in the prior quarter.
  • The five-year high for EBT was $8.2 million in Q3 2025, with the low at -$24.8 million in Q2 2025.
  • Average EBT over 4 years is -$14.4 million, with a median of -$16.6 million recorded in 2024.
  • Year-over-year, EBT plunged 88.75% in 2024 and jumped 139.56% in 2025.
  • Tracing SEPN's EBT over 4 years: stood at -$18.2 million in 2023, then retreated by 14.74% to -$20.8 million in 2024, then soared by 48.5% to -$10.7 million in 2025, then advanced by 22.62% to -$8.3 million in 2026.
  • The last three EBT figures came in at -$8.3 million (Q1 2026), -$10.7 million (Q4 2025), and $8.2 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBT (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -2.99 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -19.60 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -15.31 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 1.25 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -3.18 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 831.20 Mn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 221.65 Mn
10 Septerna 1.34 Bn 1.34 Bn - -8.30 Mn

Historic Data

Download Data 🔒
DateValue
Mar 31, 2026 -8.30 Mn
Dec 31, 2025 -10.73 Mn
Sep 30, 2025 8.17 Mn
Jun 30, 2025 -24.84 Mn
Mar 31, 2025 -21.48 Mn
Dec 31, 2024 -20.83 Mn
Sep 30, 2024 -20.66 Mn
Jun 30, 2024 -16.55 Mn
Mar 31, 2024 -14.26 Mn
Dec 31, 2023 -18.15 Mn
Sep 30, 2023 -10.95 Mn