Septerna (SEPN) EBT (2023 - 2026)
Septerna's (SEPN) quarterly EBT came in at -$8.3 million in Q1 2026, up 61.35% year-on-year from -$5.1 million in Q1 2025, and up 22.62% quarter-over-quarter from -$10.7 million in Q4 2025.
Septerna (SEPN) EBT (2023 - 2026) Analysis & Trends
Septerna's EBT history runs 4 years deep, the most recent figure standing at -$8.3 million for Q1 2026.
- On a quarterly basis, EBT rose 61.35% year-over-year to -$8.3 million in Q1 2026; TTM through Mar 2026 was -$35.7 million, a 55.11% increase from a year earlier, with the FY2025 full-year figure at -$48.9 million, up 32.41% from the prior year.
- EBT advanced to -$8.3 million in Q1 2026 per SEPN's latest filing, from -$10.7 million in the prior quarter.
- Across five years, EBT topped out at $8.2 million in Q3 2025 and bottomed at -$24.8 million in Q2 2025.
- The 4-year median for EBT is -$16.6 million (2024), against an average of -$14.4 million.
- Across the five-year window, EBT plunged 88.75% in 2024 and jumped 139.56% in 2025, its largest moves.
- Year by year, EBT stood at -$18.2 million in 2023, then fell by 14.74% to -$20.8 million in 2024, then surged by 48.5% to -$10.7 million in 2025, then gained by 22.62% to -$8.3 million in 2026.
- Per Business Quant, the three latest SEPN EBT figures stand at -$8.3 million (Q1 2026), -$10.7 million (Q4 2025), and $8.2 million (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBT (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 67,072.09 Bn | 67,072.09 Bn | - | -36.97 Mn |
| 2 | Nanobiotix | 1,894.61 Bn | 1,894.55 Bn | - | - |
| 3 | Akari Therapeutics | 1,014.18 Bn | 1,014.18 Bn | - | -15.31 Mn |
| 4 | BeOne Medicines | 471.64 Bn | 466.85 Bn | 1.35 Bn | 259.22 Mn |
| 5 | Vertex Pharmaceuticals | 121.72 Bn | 114.47 Bn | 2.59 Bn | 1.25 Bn |
| 6 | Regeneron Pharmaceuticals | 68.28 Bn | 59.52 Bn | 3.31 Bn | 831.20 Mn |
| 7 | Belite Bio | 61.40 Bn | 61.40 Bn | - | -26.94 Mn |
| 8 | Argenx Se | 56.94 Bn | 56.94 Bn | 1.18 Bn | 438.00 Mn |
| 9 | Revolution Medicines | 37.37 Bn | 37.37 Bn | - | -453.82 Mn |
| 10 | Septerna | 1.48 Bn | 1.48 Bn | - | -8.30 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -8.30 Mn |
| Dec 31, 2025 | -10.73 Mn |
| Sep 30, 2025 | 8.17 Mn |
| Jun 30, 2025 | -24.84 Mn |
| Mar 31, 2025 | -21.48 Mn |
| Dec 31, 2024 | -20.83 Mn |
| Sep 30, 2024 | -20.66 Mn |
| Jun 30, 2024 | -16.55 Mn |
| Mar 31, 2024 | -14.26 Mn |
| Dec 31, 2023 | -18.15 Mn |
| Sep 30, 2023 | -10.95 Mn |