Septerna (SEPN) EBT (2023 - 2026)
Septerna (SEPN) posted quarterly EBT of -$8.3 million for Q1 2026, up 61.35% year-over-year from -$5.1 million in Q1 2025, and up 22.62% quarter-over-quarter from -$10.7 million in Q4 2025.
Septerna (SEPN) EBT (2023 - 2026) Analysis & Trends
Septerna's EBT history runs 4 years deep, the most recent figure standing at -$8.3 million for Q1 2026.
- In Q1 2026, EBT rose 61.35% year-over-year to -$8.3 million; the TTM figure through Mar 2026 stood at -$35.7 million (up 55.11% YoY), while the FY2025 annual figure was -$48.9 million, up 32.41% from the prior year.
- EBT for Q1 2026 stood at -$8.3 million, up from -$10.7 million in the prior quarter.
- The five-year high for EBT was $8.2 million in Q3 2025, with the low at -$24.8 million in Q2 2025.
- The 4-year median for EBT is -$16.6 million (2024), against an average of -$14.4 million.
- The sharpest annual moves came in 2024 and 2025: EBT tumbled 88.75% in 2024, then jumped 139.56% in 2025.
- Septerna's EBT stood at -$18.2 million in 2023, then declined by 14.74% to -$20.8 million in 2024, then jumped by 48.5% to -$10.7 million in 2025, then rose by 22.62% to -$8.3 million in 2026.
- Business Quant data shows SEPN's EBT at -$8.3 million in Q1 2026, -$10.7 million in Q4 2025, and $8.2 million in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBT (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 128.13 Bn | 120.28 Bn | 2.84 Bn | 1.39 Bn |
| 2 | Regeneron Pharmaceuticals | 112.33 Bn | 104.33 Bn | 3.93 Bn | 1.53 Bn |
| 3 | Argenx Se | 53.24 Bn | 48.05 Bn | 1.41 Bn | 541.00 Mn |
| 4 | Revolution Medicines | 43.64 Bn | 43.64 Bn | - | -644.37 Mn |
| 5 | BeOne Medicines | 39.27 Bn | 34.17 Bn | 1.53 Bn | 312.46 Mn |
| 6 | MindWalk Holdings | 35.32 Bn | 35.31 Bn | 1.82 Bn | -2,828.29 |
| 7 | Royalty Pharma | 33.72 Bn | 35.84 Bn | - | 81.49 Mn |
| 8 | Alnylam Pharmaceuticals | 30.58 Bn | 27.27 Bn | 992.69 Mn | 177.81 Mn |
| 9 | Insmed | 27.01 Bn | 25.85 Bn | 358.27 Mn | -11.37 Mn |
| 10 | Septerna | 2.08 Bn | 2.08 Bn | - | -12.06 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | -12.06 Mn |
| Mar 31, 2026 | -8.30 Mn |
| Dec 31, 2025 | -10.73 Mn |
| Sep 30, 2025 | 8.17 Mn |
| Jun 30, 2025 | -24.84 Mn |
| Mar 31, 2025 | -21.48 Mn |
| Dec 31, 2024 | -20.83 Mn |
| Sep 30, 2024 | -20.66 Mn |
| Jun 30, 2024 | -16.55 Mn |
| Mar 31, 2024 | -14.26 Mn |
| Dec 31, 2023 | -18.15 Mn |
| Sep 30, 2023 | -10.95 Mn |