Septerna (SEPN) EBITDA (2023 - 2026)

Septerna has reported EBITDA over the past 4 years, most recently at -$9.8 million for Q1 2026.

  • For Q1 2026, EBITDA rose 53.96% year-over-year to -$9.8 million; the TTM value through Mar 2026 reached $15.7 million, up 118.96%, while the annual FY2025 figure was -$10.3 million, 87.3% up from the prior year.
  • EBITDA for Q1 2026 was -$9.8 million at Septerna, down from $42.0 million in the prior quarter.
  • Over five years, EBITDA peaked at $42.0 million in Q4 2025 and troughed at -$24.9 million in Q2 2025.
  • A 4-year average of -$5.3 million and a median of -$14.2 million in 2024 define the central range for EBITDA.
  • Biggest five-year swings in EBITDA: crashed 172.03% in 2024 and later skyrocketed 269.97% in 2025.
  • Year by year, EBITDA stood at $34.3 million in 2023, then crashed by 172.03% to -$24.7 million in 2024, then skyrocketed by 269.97% to $42.0 million in 2025, then crashed by 123.38% to -$9.8 million in 2026.
  • Business Quant data shows EBITDA for SEPN at -$9.8 million in Q1 2026, $42.0 million in Q4 2025, and $8.4 million in Q3 2025.