Septerna SEPN
NASDAQ SEPN
$51.11 +0.37 (+0.73%)
As of: Nov 10, 2026 · 2:50 PM EST

Septerna (SEPN) EBITDA (2023 - 2026)

Updated

Septerna (SEPN) posted EBITDA of -$16.41 million for Q2 2026, compared with -$28.57 million a year earlier.

Analysis

Septerna (SEPN) EBITDA (2023 - 2026) Analysis & Trends

For the trailing twelve months through Jun 30, 2026, EBITDA at Septerna was -$41.9 million; for FY2025, it came in at -$66.69 million.

  • In prior years, Septerna's EBITDA was -$79.42 million in FY2024 and $2.92 million in FY2023.
  • Quarterly EBITDA has run from a low of -$28.57 million in Q2 2025 to a high of $34.56 million in Q4 2023 over five years.
  • According to Business Quant data, EBITDA for the three prior quarters was -$12.88 million (Q1 2026), -$15.62 million (Q4 2025) and $3.02 million (Q3 2025).
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Eli Lilly 1,264.65 Bn 1,238.27 Bn 20.46 Bn 13.33 Bn
2 Johnson & Johnson 677.74 Bn 597.60 Bn 17.30 Bn 8.30 Bn
3 AbbVie 517.10 Bn 485.11 Bn 13.12 Bn 8.16 Bn
4 Merck 362.23 Bn 325.17 Bn 13.19 Bn 7.37 Bn
5 Novartis Ag 315.90 Bn 276.16 Bn 11.24 Bn -
6 Astrazeneca 289.40 Bn 266.24 Bn 12.86 Bn -
7 Amgen 249.90 Bn 201.56 Bn 7.58 Bn 4.83 Bn
8 Gilead Sciences 209.15 Bn 184.26 Bn 6.73 Bn 4.20 Bn
9 Pfizer 165.88 Bn 113.23 Bn 12.56 Bn 7.05 Bn
10 Septerna 2.27 Bn 687.56 Mn - -16.41 Mn
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 -16.41 Mn
Mar 31, 2026 -12.88 Mn
Dec 31, 2025 -15.62 Mn
Sep 30, 2025 3.02 Mn
Jun 30, 2025 -28.57 Mn
Mar 31, 2025 -25.51 Mn
Dec 31, 2024 -24.33 Mn
Sep 30, 2024 -22.19 Mn
Jun 30, 2024 -17.73 Mn
Mar 31, 2024 -15.17 Mn
Dec 31, 2023 34.56 Mn
API Access

Septerna EBITDA API

Pull this series into your own models, spreadsheets and apps with the Business Quant Historical Metrics API. The request below matches the chart above — change the frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.

https://data.businessquant.com/historic?slug=ebitda&ticker=SEPN&period=max&api_key=YOUR_API_KEY