Septerna (SEPN) EBITDA (2023 - 2026)

Septerna's EBITDA history runs 4 years deep, the most recent figure standing at -$13.3 million for Q1 2026.

• On a quarterly basis, EBITDA rose 48.67% year-over-year to -$13.3 million in Q1 2026; TTM through Mar 2026 was -$55.7 million, a 38.97% increase from a year earlier, with the FY2025 full-year figure at -$68.3 million, up 15.5% from the prior year.
• EBITDA rose to -$13.3 million in Q1 2026 per SEPN's latest filing, from -$16.0 million in the prior quarter.
• Across five years, EBITDA topped out at $34.3 million in Q4 2023 and bottomed at -$29.0 million in Q2 2025.
• The 4-year median for EBITDA is -$16.0 million (2025), against an average of -$12.7 million.
• Across the five-year window, EBITDA plunged 172.03% in 2024 and soared 111.59% in 2025, its largest moves.
• Year by year, EBITDA stood at $34.3 million in 2023, then tumbled by 172.03% to -$24.7 million in 2024, then surged by 35.18% to -$16.0 million in 2025, then gained by 16.99% to -$13.3 million in 2026.
• Per Business Quant, the three latest SEPN EBITDA figures stand at -$13.3 million (Q1 2026), -$16.0 million (Q4 2025), and $2.6 million (Q3 2025).