Septerna (SEPN) EBITDA (2023 - 2025)
Septerna has reported EBITDA over the past 3 years, most recently at -$16.0 million for Q4 2025.
- Quarterly results put EBITDA at -$16.0 million for Q4 2025, up 35.18% from a year ago — trailing twelve months through Dec 2025 was -$53.8 million (up 28.84% YoY), and the annual figure for FY2025 was -$68.3 million, up 15.5%.
- EBITDA for Q4 2025 was -$16.0 million at Septerna, down from $8.4 million in the prior quarter.
- Over the last five years, EBITDA for SEPN hit a ceiling of $34.3 million in Q4 2023 and a floor of -$24.9 million in Q2 2025.
- Median EBITDA over the past 3 years was -$16.2 million (2024), compared with a mean of -$10.6 million.
- Biggest five-year swings in EBITDA: tumbled 172.03% in 2024 and later soared 141.16% in 2025.
- Septerna's EBITDA stood at $34.3 million in 2023, then tumbled by 172.03% to -$24.7 million in 2024, then soared by 35.18% to -$16.0 million in 2025.
- The last three reported values for EBITDA were -$16.0 million (Q4 2025), $8.4 million (Q3 2025), and -$24.9 million (Q2 2025) per Business Quant data.