Septerna (SEPN) EBIT (2023 - 2026)
Septerna's quarterly EBIT came in at -$13.3 million in Q1 2026, up 48.67% year-on-year from -$8.9 million in Q1 2025, and down 131.66% quarter-over-quarter from $42.0 million in Q4 2025.
Septerna has reported EBIT for 4 years, with the latest figure at -$13.3 million in Q1 2026.
- For the quarter ending Q1 2026, EBIT rose 48.67% year-over-year to -$13.3 million; the trailing twelve-month figure through Mar 2026 stood at $2.3 million (up 102.57% YoY), and the FY2025 full-year result was -$10.3 million, up 87.3% from the prior year.
- EBIT for Q1 2026 stood at -$13.3 million, down from $42.0 million in the prior quarter.
- The five-year high for EBIT was $42.0 million in Q4 2025, with the low at -$29.0 million in Q2 2025.
- Average EBIT over 4 years is -$7.5 million, with a median of -$15.5 million recorded in 2024.
- Year-over-year, EBIT plunged 172.03% in 2024 and soared 269.97% in 2025.
- Tracing SEPN's EBIT over 4 years: stood at $34.3 million in 2023, then plunged by 172.03% to -$24.7 million in 2024, then soared by 269.97% to $42.0 million in 2025, then slumped by 131.66% to -$13.3 million in 2026.
- The last three EBIT figures came in at -$13.3 million (Q1 2026), $42.0 million (Q4 2025), and $2.6 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBIT (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 961,148.99 Bn | 961,148.98 Bn | - | -2.97 Mn |
| 2 | Alterity Therapeutics | 744,933.29 Bn | 744,933.26 Bn | - | - |
| 3 | Legend Biotech | 2,540.00 Bn | 2,539.71 Bn | 242.10 Mn | -19.70 Mn |
| 4 | Nanobiotix | 2,199.85 Bn | 2,199.78 Bn | - | - |
| 5 | Akari Therapeutics | 1,635.88 Bn | 1,635.88 Bn | - | -15.76 Mn |
| 6 | Vertex Pharmaceuticals | 111.32 Bn | 104.07 Bn | 2.59 Bn | 1.14 Bn |
| 7 | Evaxion A | 62.56 Bn | 62.54 Bn | - | -3.82 Mn |
| 8 | Regeneron Pharmaceuticals | 62.55 Bn | 53.79 Bn | 3.31 Bn | 642.90 Mn |
| 9 | Alnylam Pharmaceuticals | 39.57 Bn | 36.56 Bn | 959.66 Mn | 268.64 Mn |
| 10 | Septerna | 1.34 Bn | 1.34 Bn | - | -13.30 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -13.30 Mn |
| Dec 31, 2025 | 42.01 Mn |
| Sep 30, 2025 | 2.61 Mn |
| Jun 30, 2025 | -28.98 Mn |
| Mar 31, 2025 | -25.91 Mn |
| Dec 31, 2024 | -24.72 Mn |
| Sep 30, 2024 | -22.55 Mn |
| Jun 30, 2024 | -18.07 Mn |
| Mar 31, 2024 | -15.49 Mn |
| Dec 31, 2023 | 34.32 Mn |
| Sep 30, 2023 | -12.04 Mn |