Scilex Holding (SCLX) Return on Invested Capital (2022 - 2025)

Scilex Holding (SCLX) posted quarterly Return on Invested Capital of 0.03% for Q4 2025, up 2.0% year-over-year from 0.03% in Q4 2024, and up 74.88% on a QoQ basis from 0.02% in Q3 2025.

Scilex Holding (SCLX) Return on Invested Capital (2022 - 2025) Analysis & Trends

Scilex Holding (SCLX) has reported Return on Invested Capital for 4 consecutive years, with 0.03% the latest figure, recorded in Q4 2025.

  • In Q4 2025, Return on Invested Capital rose 2.0% year-over-year to 0.03%; the TTM figure through Dec 2025 stood at 0.03% (up 2.0% YoY), while the FY2025 annual figure was 0.02%, up 2.0% from the prior year.
  • Return on Invested Capital came in at 0.03% for Q4 2025 at Scilex Holding, up from 0.02% in the prior quarter.
  • The five-year high for Return on Invested Capital was 0.1% in Q3 2023, with the low at 0.04% in Q2 2023.
  • Average Return on Invested Capital over 4 years is 0.01%, with a median of 0.01% recorded in 2024.
  • The largest YoY upside for Return on Invested Capital was 5 bps in 2024 against a maximum downside of 10 bps in 2024.
  • Year by year, Return on Invested Capital stood at 0.01% in 2022, then jumped by 259 bps to 0.02% in 2023, then tumbled by 69 bps to 0.01% in 2024, then soared by 361 bps to 0.03% in 2025.
  • According to Business Quant data, Return on Invested Capital over the past three periods registered 0.03%, 0.02%, and 0.01% for Q4 2025, Q3 2025, and Q2 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROIC (Qtr)
1 Eli Lilly 1,066.16 Bn 1,060.88 Bn 16.22 Bn 0.00%
2 Johnson & Johnson 611.69 Bn 589.64 Bn 15.96 Bn 0.00%
3 AbbVie 444.34 Bn 434.99 Bn 10.78 Bn 0.00%
4 Astrazeneca 284.94 Bn 277.05 Bn 12.61 Bn -
5 Merck 224.23 Bn 218.58 Bn 12.09 Bn 0.00%
6 Amgen 195.12 Bn 183.08 Bn 5.87 Bn 0.00%
7 Gilead Sciences 156.45 Bn 148.73 Bn 5.52 Bn 0.00%
8 Pfizer 136.01 Bn 123.24 Bn -1.21 Bn 0.00%
9 Novartis Ag 113.45 Bn 113.67 Bn - -
10 Scilex Holding 54.30 Mn -95.62 Mn 4.15 Mn -

Historic Data

Download Data
DateValue
Dec 31, 2025 0.03%
Sep 30, 2025 0.02%
Jun 30, 2025 0.01%
Dec 31, 2024 0.01%
Sep 30, 2024 0.01%
Jun 30, 2024 0.01%
Mar 31, 2024 0.01%
Dec 31, 2023 0.02%
Sep 30, 2023 0.10%
Jun 30, 2023 -0.04%
Mar 31, 2023 -0.03%
Dec 31, 2022 0.01%