Scilex Holding Co (SCLX) Institutional Ownership

Ownership Summary

Scilex Holding Co (NASDAQ:SCLX) currently has 80 active institutional owners and shareholders as of today (December 2025), that have filed 13F forms with the Securities Exchange Commission (SEC).

• The percentage of Scilex Holding owned by institutions changed from 6.8% in September 2025 to 10.0% in December 2025, marking a slight up trend.
• On a quarter-over-quarter basis, institutional holdings shifted by 82.03%, with a year-over-year a decrease of 20.00% in the count of filers.
• During the quarter, 23 institutions bought more Scilex Holding shares, 14 sold shares, and 43 of the 80 total investors held their position steady.
• Collectively, institutional investors increased their stake in Scilex Holding to 1.12Mn shares as of December 2025, a change that is up by 504.63K shares quarter on quarter and down 280.64K shares year over year.
• With 476.67K shares, ARMISTICE CAPITAL, LLC commands the largest institutional position in Scilex Holding as of December 31, 2025, equating to 4.27% of the company.
• Among the most significant buyers of Scilex Holding during December 2025 were ARMISTICE CAPITAL, LLC (410.67K), 683 Capital Management, LLC (27.31K), XTX Topco Ltd (20.44K), CITIGROUP INC (19.85K), RENAISSANCE TECHNOLOGIES LLC (19.30K).
• Leading sellers of Scilex Holding stock in December 2025 included UBS Group AG (13.85K), BANK OF AMERICA CORP /DE/ (9.98K), MORGAN STANLEY (8.55K), BNP PARIBAS FINANCIAL MARKETS (7.41K), NORTHERN TRUST CORP (124).
• The top 10 institutional holders of Scilex Holding for the quarter ending December 2025 included ARMISTICE CAPITAL, LLC (476.67K), VANGUARD GROUP INC (295.02K), BlackRock, Inc. (98.33K), RENAISSANCE TECHNOLOGIES LLC (38.46K), STATE STREET CORP (34.35K), 683 Capital Management, LLC (27.31K), XTX Topco Ltd (20.44K), CITIGROUP INC (19.85K), Ashton Thomas Private Wealth, LLC (17.99K), NORTHERN TRUST CORP (15.03K).