Scilex Holding (SCLX) EBITDA Margin (2022 - 2026)
Scilex Holding (SCLX) posted EBITDA Margin of -347.87% for Q2 2026, down 150.93 percentage points from -196.94% a year earlier and down 7.32 percentage points from the prior quarter.
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Analysis
Scilex Holding (SCLX) EBITDA Margin (2022 - 2026) Analysis & Trends
For the trailing twelve months through Jun 30, 2026, EBITDA Margin at Scilex Holding was -1108.54%, down 899.09 percentage points year-over-year; for FY2025, it came in at -1126.68%, down 986.49 percentage points from FY2024.
- Annual EBITDA Margin shows a five-year change of -993.06 percentage points (FY2020 to FY2025).
- In prior years, Scilex Holding's EBITDA Margin was -140.19% in FY2024 (+76.49 pp), -216.68% in FY2023 (-93.97 pp), -122.71% in FY2022 (-20.34 pp) and -102.37% in FY2021 (+31.25 pp).
- Quarterly EBITDA Margin has run from a low of -2262.46% in Q4 2025 to a high of -84.20% in Q3 2022 over five years.
- On a year-over-year basis, EBITDA Margin increased in two of the last eight quarters, with an average year-over-year change of -493.35 percentage points.
- The strongest year-over-year quarter for EBITDA Margin in the past five years was Q3 2024, with a gain of 242.29 percentage points; the weakest was Q4 2025, with a drop of 2078.86 percentage points.
- According to Business Quant data, EBITDA Margin for the three prior quarters was -340.54% (Q1 2026), -2262.46% (Q4 2025) and -1756.52% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 645.01 Bn | 563.54 Bn | 17.26 Bn | 35.95% |
| 2 | AbbVie | 465.23 Bn | 438.39 Bn | 12.70 Bn | 49.01% |
| 3 | Merck | 368.40 Bn | 322.83 Bn | 12.21 Bn | 6.02% |
| 4 | Novartis Ag | 278.02 Bn | 233.89 Bn | 11.24 Bn | - |
| 5 | Astrazeneca | 254.57 Bn | 228.13 Bn | 12.86 Bn | 33.11% |
| 6 | Amgen | 229.02 Bn | 184.42 Bn | 7.24 Bn | 46.01% |
| 7 | Gilead Sciences | 187.74 Bn | 161.85 Bn | 6.22 Bn | -124.26% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 39.16% |
| 9 | Vertex Pharmaceuticals | 133.45 Bn | 105.45 Bn | 2.84 Bn | 39.10% |
| 10 | Scilex Holding | 31.02 Mn | 19.00 Mn | 3.97 Mn | -347.87% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -347.87% |
| Mar 31, 2026 | -340.54% |
| Dec 31, 2025 | -2,262.46% |
| Sep 30, 2025 | -1,756.52% |
| Jun 30, 2025 | -196.94% |
| Mar 31, 2025 | -537.47% |
| Dec 31, 2024 | -183.59% |
| Sep 30, 2024 | -131.01% |
| Jun 30, 2024 | -89.29% |
| Mar 31, 2024 | -169.49% |
| Dec 31, 2023 | -128.55% |
| Sep 30, 2023 | -373.29% |
| Jun 30, 2023 | -173.09% |
| Mar 31, 2023 | -230.92% |
| Dec 31, 2022 | -156.94% |
| Sep 30, 2022 | -84.20% |
| Jun 30, 2022 | -132.79% |
| Mar 31, 2022 | -115.41% |
API Access
Scilex Holding EBITDA Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=ebitda-margin&ticker=SCLX&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "ebitda-margin", "ticker": "SCLX", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=ebitda-margin&ticker=SCLX&period=max&api_key=YOUR_API_KEY");
const data = await res.json();