Scilex Holding (SCLX) EBITDA Margin (2022 - 2026)

Scilex Holding (SCLX) posted quarterly EBITDA Margin of 374.06% for Q1 2026, up 18390.0% year-over-year from N/an in Q1 2025, and up 54.67% on a QoQ basis from 825.12% in Q4 2025.

Scilex Holding (SCLX) EBITDA Margin (2022 - 2026) Analysis & Trends

Scilex Holding (SCLX) has reported EBITDA Margin for 5 consecutive years, with 374.06% the latest figure, recorded in Q1 2026.

  • In Q1 2026, EBITDA Margin rose 18390.0% year-over-year to 374.06%; the TTM figure through Mar 2026 stood at 1112.06% (down 97399.0% YoY), while the FY2025 annual figure was 1223.94%, down 110645.0% from the prior year.
  • EBITDA Margin came in at 374.06% for Q1 2026 at Scilex Holding, up from 825.12% in the prior quarter.
  • The five-year high for EBITDA Margin was 8.51% in Q3 2024, with the low at 2469.6% in Q3 2025.
  • Average EBITDA Margin over 5 years is 388.69%, with a median of 211.8% recorded in 2023.
  • Across the five-year window, EBITDA Margin surged 34267 bps in 2024 and sank 246110 bps in 2025, its largest moves.
  • Year by year, EBITDA Margin stood at 165.63% in 2022, then advanced by 4 bps to 158.97% in 2023, then soared by 78 bps to 34.59% in 2024, then slumped by 2285 bps to 825.12% in 2025, then jumped by 55 bps to 374.06% in 2026.
  • According to Business Quant data, EBITDA Margin over the past three periods registered 374.06%, 825.12%, and 2469.6% for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA Margin (Qtr)
1 Eli Lilly 1,066.16 Bn 1,060.88 Bn 16.22 Bn 47.98%
2 Johnson & Johnson 611.69 Bn 589.64 Bn 15.96 Bn 26.44%
3 AbbVie 444.34 Bn 434.99 Bn 10.78 Bn 26.60%
4 Astrazeneca 284.94 Bn 277.05 Bn 12.61 Bn 18.85%
5 Merck 224.23 Bn 218.58 Bn 12.09 Bn -47.46%
6 Amgen 195.12 Bn 183.08 Bn 5.87 Bn 30.94%
7 Gilead Sciences 156.45 Bn 148.73 Bn 5.52 Bn 37.16%
8 Pfizer 136.01 Bn 123.24 Bn -1.21 Bn -286.83%
9 Novartis Ag 113.45 Bn 113.67 Bn - -
10 Scilex Holding 54.30 Mn -95.62 Mn 4.15 Mn -374.06%

Historic Data

Download Data
DateValue
Mar 31, 2026 -374.06%
Dec 31, 2025 -825.12%
Sep 30, 2025 -2,469.60%
Jun 30, 2025 -445.11%
Mar 31, 2025 -557.96%
Dec 31, 2024 -34.59%
Sep 30, 2024 -8.51%
Jun 30, 2024 -218.27%
Mar 31, 2024 -178.96%
Dec 31, 2023 -158.97%
Sep 30, 2023 -351.18%
Jun 30, 2023 -211.80%
Mar 31, 2023 -240.72%
Dec 31, 2022 -165.63%
Sep 30, 2022 -93.31%
Jun 30, 2022 -144.73%
Mar 31, 2022 -129.27%