Regenxbio (RGNX) Operating Income (2014 - 2025)

Regenxbio (RGNX) recorded quarterly Operating Income of -$57.6 million in Q4 2025, down 9.97% quarter-over-quarter from -$52.4 million in Q3 2025, and down 12.2% on a YoY basis from -$65.6 million in Q4 2024.

Regenxbio (RGNX) Operating Income (2014 - 2025) Analysis & Trends

Regenxbio's Operating Income history runs 12 years deep, the most recent figure standing at -$57.6 million for Q4 2025.

  • In Q4 2025, Operating Income fell 12.2% year-over-year to -$57.6 million; the TTM figure through Dec 2025 stood at -$161.2 million (up 30.92% YoY), while the FY2025 annual figure was -$161.2 million, up 30.92% from the prior year.
  • Operating Income was -$57.6 million for Q4 2025 at Regenxbio, down from -$52.4 million in the prior quarter.
  • In the past five years, Operating Income ranged from a high of $313.6 million in Q4 2021 to a low of -$73.1 million in Q2 2023.
  • Historically, Operating Income has averaged -$38.3 million across 5 years, with a median of -$59.9 million in 2022.
  • Biggest YoY gain for Operating Income was 684.51% in 2021; the steepest drop was 511.07% in 2021.
  • A 5-year view of Operating Income shows it stood at $313.6 million in 2021, then sank by 118.42% to -$57.8 million in 2022, then decreased by 10.61% to -$63.9 million in 2023, then climbed by 19.62% to -$51.4 million in 2024, then retreated by 12.2% to -$57.6 million in 2025.
  • The last three Operating Income figures came in at -$57.6 million (Q4 2025), -$52.4 million (Q3 2025), and -$63.3 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Alterity Therapeutics 788,338.31 Bn 788,338.28 Bn - -
2 Belite Bio 56,560.00 Bn 56,560.00 Bn - -32.68 Mn
3 Quantum Biopharma 17,329.30 Bn 17,329.30 Bn - -2.97 Mn
4 Legend Biotech 3,341.00 Bn 3,340.71 Bn 242.10 Mn -19.70 Mn
5 Akari Therapeutics 1,727.91 Bn 1,727.91 Bn - -15.76 Mn
6 Evaxion A 1,536.68 Bn 1,536.67 Bn - -3.82 Mn
7 Psyence Biomedical 238.34 Bn 238.33 Bn - -
8 Vertex Pharmaceuticals 113.42 Bn 106.17 Bn 2.59 Bn 1.14 Bn
9 Abivax 95.45 Bn 95.45 Bn - -65.83 Mn
10 Regenxbio 325.94 Mn 95.87 Mn - -57.64 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -57.64 Mn
Sep 30, 2025 -52.41 Mn
Jun 30, 2025 -63.28 Mn
Mar 31, 2025 12.13 Mn
Dec 31, 2024 -51.37 Mn
Sep 30, 2024 -62.08 Mn
Jun 30, 2024 -56.04 Mn
Mar 31, 2024 -63.86 Mn
Dec 31, 2023 -63.90 Mn
Sep 30, 2023 -64.96 Mn
Jun 30, 2023 -73.11 Mn
Mar 31, 2023 -66.16 Mn
Dec 31, 2022 -57.77 Mn
Sep 30, 2022 -71.05 Mn
Jun 30, 2022 -62.53 Mn
Mar 31, 2022 -71.53 Mn
Dec 31, 2021 313.60 Mn
Sep 30, 2021 -57.35 Mn
Jun 30, 2021 -52.23 Mn
Mar 31, 2021 -44.04 Mn