Regenxbio (RGNX) Operating Income (2014 - 2025)
Regenxbio (RGNX) recorded quarterly Operating Income of -$57.6 million in Q4 2025, down 9.97% quarter-over-quarter from -$52.4 million in Q3 2025, and down 12.2% on a YoY basis from -$65.6 million in Q4 2024.
Regenxbio (RGNX) Operating Income (2014 - 2025) Analysis & Trends
Regenxbio's Operating Income history runs 12 years deep, the most recent figure standing at -$57.6 million for Q4 2025.
- In Q4 2025, Operating Income fell 12.2% year-over-year to -$57.6 million; the TTM figure through Dec 2025 stood at -$161.2 million (up 30.92% YoY), while the FY2025 annual figure was -$161.2 million, up 30.92% from the prior year.
- Operating Income was -$57.6 million for Q4 2025 at Regenxbio, down from -$52.4 million in the prior quarter.
- In the past five years, Operating Income ranged from a high of $313.6 million in Q4 2021 to a low of -$73.1 million in Q2 2023.
- Historically, Operating Income has averaged -$38.3 million across 5 years, with a median of -$59.9 million in 2022.
- Biggest YoY gain for Operating Income was 684.51% in 2021; the steepest drop was 511.07% in 2021.
- A 5-year view of Operating Income shows it stood at $313.6 million in 2021, then sank by 118.42% to -$57.8 million in 2022, then decreased by 10.61% to -$63.9 million in 2023, then climbed by 19.62% to -$51.4 million in 2024, then retreated by 12.2% to -$57.6 million in 2025.
- The last three Operating Income figures came in at -$57.6 million (Q4 2025), -$52.4 million (Q3 2025), and -$63.3 million (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Op. Inc (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 788,338.31 Bn | 788,338.28 Bn | - | - |
| 2 | Belite Bio | 56,560.00 Bn | 56,560.00 Bn | - | -32.68 Mn |
| 3 | Quantum Biopharma | 17,329.30 Bn | 17,329.30 Bn | - | -2.97 Mn |
| 4 | Legend Biotech | 3,341.00 Bn | 3,340.71 Bn | 242.10 Mn | -19.70 Mn |
| 5 | Akari Therapeutics | 1,727.91 Bn | 1,727.91 Bn | - | -15.76 Mn |
| 6 | Evaxion A | 1,536.68 Bn | 1,536.67 Bn | - | -3.82 Mn |
| 7 | Psyence Biomedical | 238.34 Bn | 238.33 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 113.42 Bn | 106.17 Bn | 2.59 Bn | 1.14 Bn |
| 9 | Abivax | 95.45 Bn | 95.45 Bn | - | -65.83 Mn |
| 10 | Regenxbio | 325.94 Mn | 95.87 Mn | - | -57.64 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -57.64 Mn |
| Sep 30, 2025 | -52.41 Mn |
| Jun 30, 2025 | -63.28 Mn |
| Mar 31, 2025 | 12.13 Mn |
| Dec 31, 2024 | -51.37 Mn |
| Sep 30, 2024 | -62.08 Mn |
| Jun 30, 2024 | -56.04 Mn |
| Mar 31, 2024 | -63.86 Mn |
| Dec 31, 2023 | -63.90 Mn |
| Sep 30, 2023 | -64.96 Mn |
| Jun 30, 2023 | -73.11 Mn |
| Mar 31, 2023 | -66.16 Mn |
| Dec 31, 2022 | -57.77 Mn |
| Sep 30, 2022 | -71.05 Mn |
| Jun 30, 2022 | -62.53 Mn |
| Mar 31, 2022 | -71.53 Mn |
| Dec 31, 2021 | 313.60 Mn |
| Sep 30, 2021 | -57.35 Mn |
| Jun 30, 2021 | -52.23 Mn |
| Mar 31, 2021 | -44.04 Mn |