Regenxbio (RGNX) Operating Income (2014 - 2025)
Regenxbio's (RGNX) quarterly Operating Income came in at -$57.6 million in Q4 2025, down 12.2% year-on-year from -$65.6 million in Q4 2024, and down 9.97% quarter-over-quarter from -$52.4 million in Q3 2025.
Regenxbio (RGNX) Operating Income (2014 - 2025) Analysis & Trends
Regenxbio's Operating Income history runs 12 years deep, the most recent figure standing at -$57.6 million for Q4 2025.
- On a quarterly basis, Operating Income fell 12.2% year-over-year to -$57.6 million in Q4 2025; TTM through Dec 2025 was -$161.2 million, a 30.92% increase from a year earlier, with the FY2025 full-year figure at -$161.2 million, up 30.92% from the prior year.
- Operating Income fell to -$57.6 million in Q4 2025 per RGNX's latest filing, from -$52.4 million in the prior quarter.
- Across five years, Operating Income topped out at $313.6 million in Q4 2021 and bottomed at -$73.1 million in Q2 2023.
- The 5-year median for Operating Income is -$59.9 million (2022), against an average of -$38.3 million.
- Biggest YoY gain for Operating Income was 684.51% in 2021; the steepest drop was 511.07% in 2021.
- Year by year, Operating Income stood at $313.6 million in 2021, then tumbled by 118.42% to -$57.8 million in 2022, then decreased by 10.61% to -$63.9 million in 2023, then climbed by 19.62% to -$51.4 million in 2024, then retreated by 12.2% to -$57.6 million in 2025.
- Per Business Quant, the three latest RGNX Operating Income figures stand at -$57.6 million (Q4 2025), -$52.4 million (Q3 2025), and -$63.3 million (Q2 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Op. Inc (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | -27.75 Mn |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 249.90 Mn |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | -3.72 Mn |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 1.14 Bn |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 642.90 Mn |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | -32.68 Mn |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | 493.00 Mn |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | -445.22 Mn |
| 10 | Regenxbio | 528.62 Mn | 298.55 Mn | 21.22 Mn | -57.64 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -57.64 Mn |
| Sep 30, 2025 | -52.41 Mn |
| Jun 30, 2025 | -63.28 Mn |
| Mar 31, 2025 | 12.13 Mn |
| Dec 31, 2024 | -51.37 Mn |
| Sep 30, 2024 | -62.08 Mn |
| Jun 30, 2024 | -56.04 Mn |
| Mar 31, 2024 | -63.86 Mn |
| Dec 31, 2023 | -63.90 Mn |
| Sep 30, 2023 | -64.96 Mn |
| Jun 30, 2023 | -73.11 Mn |
| Mar 31, 2023 | -66.16 Mn |
| Dec 31, 2022 | -57.77 Mn |
| Sep 30, 2022 | -71.05 Mn |
| Jun 30, 2022 | -62.53 Mn |
| Mar 31, 2022 | -71.53 Mn |
| Dec 31, 2021 | 313.60 Mn |
| Sep 30, 2021 | -57.35 Mn |
| Jun 30, 2021 | -52.23 Mn |
| Mar 31, 2021 | -44.04 Mn |