Regenxbio (RGNX) Net Margin (2014 - 2025)

Regenxbio (RGNX) recorded quarterly Net Margin of 221.4% in Q4 2025, down 6.25% quarter-over-quarter from 208.39% in Q3 2025, and up 2027.0% on a YoY basis from 10.41% in Q4 2024.

Regenxbio (RGNX) Net Margin (2014 - 2025) Analysis & Trends

Regenxbio's Net Margin history runs 12 years deep, the most recent figure standing at 221.4% for Q4 2025.

  • In Q4 2025, Net Margin rose 2027.0% year-over-year to 221.4%; the TTM figure through Dec 2025 stood at 113.8% (up 15895.0% YoY), while the FY2025 annual figure was 113.8%, up 15874.0% from the prior year.
  • Net Margin was 221.4% for Q4 2025 at Regenxbio, down from 208.39% in the prior quarter.
  • In the past five years, Net Margin ranged from a high of 703.16% in Q4 2022 to a low of 405.63% in Q1 2024.
  • Historically, Net Margin has averaged 193.59% across 5 years, with a median of 244.04% in 2024.
  • The sharpest annual moves came in 2022 and 2023: Net Margin jumped 62941 bps in 2022, then tumbled 98664 bps in 2023.
  • A 5-year view of Net Margin shows it stood at 73.75% in 2021, then soared by 853 bps to 703.16% in 2022, then slumped by 140 bps to 283.48% in 2023, then climbed by 15 bps to 241.68% in 2024, then climbed by 8 bps to 221.4% in 2025.
  • The last three Net Margin figures came in at 221.4% (Q4 2025), 208.39% (Q3 2025), and 331.91% (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Margin (Qtr)
1 Alterity Therapeutics 719,706.53 Bn 719,706.50 Bn - -
2 Belite Bio 55,800.00 Bn 55,800.00 Bn - -
3 Quantum Biopharma 18,182.30 Bn 18,182.29 Bn - -
4 Legend Biotech 3,154.00 Bn 3,153.71 Bn 242.10 Mn 0.82%
5 Akari Therapeutics 1,844.30 Bn 1,844.29 Bn - -
6 Evaxion A 1,567.96 Bn 1,567.94 Bn - -
7 Psyence Biomedical 251.43 Bn 251.42 Bn - -
8 Vertex Pharmaceuticals 112.56 Bn 105.31 Bn 2.59 Bn 34.53%
9 Abivax 94.37 Bn 94.37 Bn - -
10 Regenxbio 315.11 Mn 85.04 Mn - -221.40%

Historic Data

Download Data
DateValue
Dec 31, 2025 -221.40%
Sep 30, 2025 -208.39%
Jun 30, 2025 -331.91%
Mar 31, 2025 6.81%
Dec 31, 2024 -241.68%
Sep 30, 2024 -246.40%
Jun 30, 2024 -237.80%
Mar 31, 2024 -405.63%
Dec 31, 2023 -283.48%
Sep 30, 2023 -213.97%
Jun 30, 2023 -360.72%
Mar 31, 2023 -348.40%
Dec 31, 2022 703.16%
Sep 30, 2022 -284.72%
Jun 30, 2022 -208.82%
Mar 31, 2022 -345.32%
Dec 31, 2021 73.75%
Sep 30, 2021 -189.79%
Jun 30, 2021 -261.58%
Mar 31, 2021 -265.51%