Regenxbio (RGNX) EBITDA (2014 - 2025)

Regenxbio (RGNX) recorded quarterly EBITDA of -$67.2 million in Q4 2025, down 8.64% quarter-over-quarter from -$61.8 million in Q3 2025, and down 30.85% on a YoY basis from -$97.2 million in Q4 2024.

Regenxbio (RGNX) EBITDA (2014 - 2025) Analysis & Trends

Regenxbio's EBITDA history runs 12 years deep, the most recent figure standing at -$67.2 million for Q4 2025.

  • In Q4 2025, EBITDA fell 30.85% year-over-year to -$67.2 million; the TTM figure through Dec 2025 stood at -$193.8 million (up 13.24% YoY), while the FY2025 annual figure was -$193.8 million, up 13.24% from the prior year.
  • EBITDA was -$67.2 million for Q4 2025 at Regenxbio, down from -$61.8 million in the prior quarter.
  • In the past five years, EBITDA ranged from a high of $292.7 million in Q4 2021 to a low of -$86.1 million in Q1 2022.
  • Historically, EBITDA has averaged -$41.9 million across 5 years, with a median of -$59.5 million in 2023.
  • Biggest YoY gain for EBITDA was 724.66% in 2021; the steepest drop was 803.7% in 2021.
  • A 5-year view of EBITDA shows it stood at $292.7 million in 2021, then slumped by 119.5% to -$57.1 million in 2022, then dropped by 4.95% to -$59.9 million in 2023, then grew by 14.29% to -$51.3 million in 2024, then tumbled by 30.85% to -$67.2 million in 2025.
  • The last three EBITDA figures came in at -$67.2 million (Q4 2025), -$61.8 million (Q3 2025), and -$70.9 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Alterity Therapeutics 719,706.53 Bn 719,706.50 Bn - -
2 Belite Bio 55,800.00 Bn 55,800.00 Bn - -26.92 Mn
3 Quantum Biopharma 18,182.30 Bn 18,182.29 Bn - -13.63 Mn
4 Legend Biotech 3,154.00 Bn 3,153.71 Bn 242.10 Mn -19.70 Mn
5 Akari Therapeutics 1,844.30 Bn 1,844.29 Bn - -14.44 Mn
6 Evaxion A 1,567.96 Bn 1,567.94 Bn - -3.82 Mn
7 Psyence Biomedical 251.43 Bn 251.42 Bn - -752,618.00
8 Vertex Pharmaceuticals 112.56 Bn 105.31 Bn 2.59 Bn 1.14 Bn
9 Abivax 94.37 Bn 94.37 Bn - -65.83 Mn
10 Regenxbio 315.11 Mn 85.04 Mn - -67.18 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -67.18 Mn
Sep 30, 2025 -61.84 Mn
Jun 30, 2025 -70.86 Mn
Mar 31, 2025 6.06 Mn
Dec 31, 2024 -51.35 Mn
Sep 30, 2024 -57.91 Mn
Jun 30, 2024 -52.03 Mn
Mar 31, 2024 -62.13 Mn
Dec 31, 2023 -59.91 Mn
Sep 30, 2023 -59.18 Mn
Jun 30, 2023 -70.54 Mn
Mar 31, 2023 -62.90 Mn
Dec 31, 2022 -57.08 Mn
Sep 30, 2022 -78.98 Mn
Jun 30, 2022 -70.99 Mn
Mar 31, 2022 -86.10 Mn
Dec 31, 2021 292.74 Mn
Sep 30, 2021 -58.44 Mn
Jun 30, 2021 -57.53 Mn
Mar 31, 2021 -51.15 Mn