Regenxbio (RGNX) EBITDA (2014 - 2025)

Regenxbio's (RGNX) quarterly EBITDA came in at -$57.6 million in Q4 2025, down 12.2% year-on-year from -$65.6 million in Q4 2024, and down 9.97% quarter-over-quarter from -$52.4 million in Q3 2025.

Regenxbio (RGNX) EBITDA (2014 - 2025) Analysis & Trends

Regenxbio's EBITDA history runs 12 years deep, the most recent figure standing at -$57.6 million for Q4 2025.

  • On a quarterly basis, EBITDA fell 12.2% year-over-year to -$57.6 million in Q4 2025; TTM through Dec 2025 was -$161.2 million, a 30.92% increase from a year earlier, with the FY2025 full-year figure at -$161.2 million, up 30.92% from the prior year.
  • EBITDA fell to -$57.6 million in Q4 2025 per RGNX's latest filing, from -$52.4 million in the prior quarter.
  • Across five years, EBITDA topped out at $313.6 million in Q4 2021 and bottomed at -$73.1 million in Q2 2023.
  • The 5-year median for EBITDA is -$59.9 million (2022), against an average of -$38.3 million.
  • Biggest YoY gain for EBITDA was 684.51% in 2021; the steepest drop was 511.07% in 2021.
  • Year by year, EBITDA stood at $313.6 million in 2021, then tumbled by 118.42% to -$57.8 million in 2022, then decreased by 10.61% to -$63.9 million in 2023, then climbed by 19.62% to -$51.4 million in 2024, then retreated by 12.2% to -$57.6 million in 2025.
  • Per Business Quant, the three latest RGNX EBITDA figures stand at -$57.6 million (Q4 2025), -$52.4 million (Q3 2025), and -$63.3 million (Q2 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -27.75 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -15.76 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 249.90 Mn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 1.14 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 642.90 Mn
7 Belite Bio 61.40 Bn 61.40 Bn - -32.68 Mn
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn 394.00 Mn
9 Revolution Medicines 37.37 Bn 37.37 Bn - -445.22 Mn
10 Regenxbio 501.81 Mn 271.74 Mn 21.22 Mn -57.64 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -57.64 Mn
Sep 30, 2025 -52.41 Mn
Jun 30, 2025 -63.28 Mn
Mar 31, 2025 12.13 Mn
Dec 31, 2024 -51.37 Mn
Sep 30, 2024 -62.08 Mn
Jun 30, 2024 -56.04 Mn
Mar 31, 2024 -63.86 Mn
Dec 31, 2023 -63.90 Mn
Sep 30, 2023 -64.96 Mn
Jun 30, 2023 -73.11 Mn
Mar 31, 2023 -66.16 Mn
Dec 31, 2022 -57.77 Mn
Sep 30, 2022 -71.05 Mn
Jun 30, 2022 -62.53 Mn
Mar 31, 2022 -71.53 Mn
Dec 31, 2021 313.60 Mn
Sep 30, 2021 -57.35 Mn
Jun 30, 2021 -52.23 Mn
Mar 31, 2021 -44.04 Mn