Replimune (REPL) Research & Development (2017 - 2025)

Replimune's (REPL) quarterly Research & Development came in at $53.1 million in Q4 2025, up 10.7% year-on-year from $48.0 million in Q4 2024, and down 8.18% quarter-over-quarter from $57.9 million in Q3 2025.

Replimune (REPL) Research & Development (2017 - 2025) Analysis & Trends

Replimune has disclosed Research & Development across 9 years of filings, most recently posting $53.1 million for Q4 2025.

  • Research & Development for Q4 2025 came in at $53.1 million, up 10.7% year-over-year; the trailing twelve-month figure through Dec 2025 was $222.8 million (up 25.89% YoY), and the FY2025 annual result was $189.4 million, up 8.28% from the prior year.
  • Research & Development came in at $53.1 million for Q4 2025 at Replimune, down from $57.9 million in the prior quarter.
  • In the past five years, Research & Development ranged from a high of $57.9 million in Q3 2025 to a low of $16.2 million in Q1 2021.
  • The 5-year median for Research & Development is $41.5 million (2023), against an average of $37.7 million.
  • Across the five-year window, Research & Development jumped 74.61% in 2023 and dropped 11.51% in 2024, its largest moves.
  • Replimune's Research & Development stood at $19.4 million in 2021, then soared by 56.36% to $30.3 million in 2022, then soared by 41.59% to $42.8 million in 2023, then advanced by 12.04% to $48.0 million in 2024, then grew by 10.7% to $53.1 million in 2025.
  • The last three Research & Development figures came in at $53.1 million (Q4 2025), $57.9 million (Q3 2025), and $57.8 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) R&D (Qtr)
1 Alterity Therapeutics 762,369.55 Bn 762,369.51 Bn - 4.32 Mn
2 Belite Bio 55,096.00 Bn 55,096.00 Bn - 15.66 Mn
3 Quantum Biopharma 17,755.80 Bn 17,755.79 Bn - 626,092.00
4 Legend Biotech 3,486.00 Bn 3,485.71 Bn 242.10 Mn -101.30 Mn
5 Akari Therapeutics 1,737.42 Bn 1,737.41 Bn - 1.46 Mn
6 Evaxion A 1,551.28 Bn 1,551.26 Bn - -2.30 Mn
7 Psyence Biomedical 227.32 Bn 227.31 Bn - 357,444.00
8 Vertex Pharmaceuticals 110.84 Bn 103.59 Bn 2.59 Bn 961.60 Mn
9 Abivax 91.71 Bn 91.71 Bn - -58.00 Mn
10 Replimune 780.01 Mn 510.88 Mn - 53.14 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 53.14 Mn
Sep 30, 2025 57.88 Mn
Jun 30, 2025 57.84 Mn
Mar 31, 2025 53.98 Mn
Dec 31, 2024 48.00 Mn
Sep 30, 2024 43.45 Mn
Jun 30, 2024 42.97 Mn
Mar 31, 2024 42.58 Mn
Dec 31, 2023 42.85 Mn
Sep 30, 2023 49.10 Mn
Jun 30, 2023 40.44 Mn
Mar 31, 2023 37.95 Mn
Dec 31, 2022 30.26 Mn
Sep 30, 2022 28.83 Mn
Jun 30, 2022 29.48 Mn
Mar 31, 2022 21.74 Mn
Dec 31, 2021 19.35 Mn
Sep 30, 2021 19.90 Mn
Jun 30, 2021 18.55 Mn
Mar 31, 2021 16.23 Mn