Replimune (REPL) Research & Development (2017 - 2025)
Replimune's (REPL) quarterly Research & Development came in at $53.1 million in Q4 2025, up 10.7% year-on-year from $48.0 million in Q4 2024, and down 8.18% quarter-over-quarter from $57.9 million in Q3 2025.
Replimune (REPL) Research & Development (2017 - 2025) Analysis & Trends
Replimune has disclosed Research & Development across 9 years of filings, most recently posting $53.1 million for Q4 2025.
- Research & Development for Q4 2025 came in at $53.1 million, up 10.7% year-over-year; the trailing twelve-month figure through Dec 2025 was $222.8 million (up 25.89% YoY), and the FY2025 annual result was $189.4 million, up 8.28% from the prior year.
- Research & Development came in at $53.1 million for Q4 2025 at Replimune, down from $57.9 million in the prior quarter.
- In the past five years, Research & Development ranged from a high of $57.9 million in Q3 2025 to a low of $16.2 million in Q1 2021.
- The 5-year median for Research & Development is $41.5 million (2023), against an average of $37.7 million.
- Across the five-year window, Research & Development jumped 74.61% in 2023 and dropped 11.51% in 2024, its largest moves.
- Replimune's Research & Development stood at $19.4 million in 2021, then soared by 56.36% to $30.3 million in 2022, then soared by 41.59% to $42.8 million in 2023, then advanced by 12.04% to $48.0 million in 2024, then grew by 10.7% to $53.1 million in 2025.
- The last three Research & Development figures came in at $53.1 million (Q4 2025), $57.9 million (Q3 2025), and $57.8 million (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | R&D (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 762,369.55 Bn | 762,369.51 Bn | - | 4.32 Mn |
| 2 | Belite Bio | 55,096.00 Bn | 55,096.00 Bn | - | 15.66 Mn |
| 3 | Quantum Biopharma | 17,755.80 Bn | 17,755.79 Bn | - | 626,092.00 |
| 4 | Legend Biotech | 3,486.00 Bn | 3,485.71 Bn | 242.10 Mn | -101.30 Mn |
| 5 | Akari Therapeutics | 1,737.42 Bn | 1,737.41 Bn | - | 1.46 Mn |
| 6 | Evaxion A | 1,551.28 Bn | 1,551.26 Bn | - | -2.30 Mn |
| 7 | Psyence Biomedical | 227.32 Bn | 227.31 Bn | - | 357,444.00 |
| 8 | Vertex Pharmaceuticals | 110.84 Bn | 103.59 Bn | 2.59 Bn | 961.60 Mn |
| 9 | Abivax | 91.71 Bn | 91.71 Bn | - | -58.00 Mn |
| 10 | Replimune | 780.01 Mn | 510.88 Mn | - | 53.14 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | 53.14 Mn |
| Sep 30, 2025 | 57.88 Mn |
| Jun 30, 2025 | 57.84 Mn |
| Mar 31, 2025 | 53.98 Mn |
| Dec 31, 2024 | 48.00 Mn |
| Sep 30, 2024 | 43.45 Mn |
| Jun 30, 2024 | 42.97 Mn |
| Mar 31, 2024 | 42.58 Mn |
| Dec 31, 2023 | 42.85 Mn |
| Sep 30, 2023 | 49.10 Mn |
| Jun 30, 2023 | 40.44 Mn |
| Mar 31, 2023 | 37.95 Mn |
| Dec 31, 2022 | 30.26 Mn |
| Sep 30, 2022 | 28.83 Mn |
| Jun 30, 2022 | 29.48 Mn |
| Mar 31, 2022 | 21.74 Mn |
| Dec 31, 2021 | 19.35 Mn |
| Sep 30, 2021 | 19.90 Mn |
| Jun 30, 2021 | 18.55 Mn |
| Mar 31, 2021 | 16.23 Mn |