Replimune (REPL) Net Cash Flow (2017 - 2025)
Replimune's (REPL) quarterly Net Cash Flow came in at $19.6 million in Q4 2025, down 66.69% year-on-year from $58.9 million in Q4 2024, and up 497.87% quarter-over-quarter from $3.3 million in Q3 2025.
Replimune (REPL) Net Cash Flow (2017 - 2025) Analysis & Trends
Replimune has disclosed Net Cash Flow across 9 years of filings, most recently posting $19.6 million for Q4 2025.
- Net Cash Flow for Q4 2025 came in at $19.6 million, down 66.69% year-over-year; the trailing twelve-month figure through Dec 2025 was -$50.8 million (down 167.89% YoY), and the FY2025 annual result was $36.4 million, up 150.5% from the prior year.
- Net Cash Flow came in at $19.6 million for Q4 2025 at Replimune, up from $3.3 million in the prior quarter.
- In the past five years, Net Cash Flow ranged from a high of $117.7 million in Q4 2022 to a low of -$141.6 million in Q1 2021.
- The 5-year median for Net Cash Flow is -$24.4 million (2022), against an average of -$10.2 million.
- Across the five-year window, Net Cash Flow tumbled 4081.16% in 2021 and jumped 523.56% in 2022, its largest moves.
- Replimune's Net Cash Flow stood at -$27.8 million in 2021, then surged by 523.56% to $117.7 million in 2022, then plunged by 81.57% to $21.7 million in 2023, then soared by 171.38% to $58.9 million in 2024, then tumbled by 66.69% to $19.6 million in 2025.
- The last three Net Cash Flow figures came in at $19.6 million (Q4 2025), $3.3 million (Q3 2025), and -$12.1 million (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Cash Flow (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 762,369.55 Bn | 762,369.51 Bn | - | - |
| 2 | Belite Bio | 55,096.00 Bn | 55,096.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,755.80 Bn | 17,755.79 Bn | - | 2.44 Mn |
| 4 | Legend Biotech | 3,486.00 Bn | 3,485.71 Bn | 242.10 Mn | 625.70 Mn |
| 5 | Akari Therapeutics | 1,737.42 Bn | 1,737.41 Bn | - | -2.44 Mn |
| 6 | Evaxion A | 1,551.28 Bn | 1,551.26 Bn | - | - |
| 7 | Psyence Biomedical | 227.32 Bn | 227.31 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 110.84 Bn | 103.59 Bn | 2.59 Bn | 457.40 Mn |
| 9 | Abivax | 91.71 Bn | 91.71 Bn | - | 664,983.53 |
| 10 | Replimune | 780.01 Mn | 510.88 Mn | - | 19.62 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | 19.62 Mn |
| Dec 31, 2025 | 19.62 Mn |
| Sep 30, 2025 | 3.28 Mn |
| Sep 30, 2025 | 3.28 Mn |
| Jun 30, 2025 | -12.13 Mn |
| Jun 30, 2025 | -12.13 Mn |
| Mar 31, 2025 | -61.56 Mn |
| Mar 31, 2025 | -61.56 Mn |
| Dec 31, 2024 | 58.90 Mn |
| Dec 31, 2024 | 58.90 Mn |
| Sep 30, 2024 | -38.22 Mn |
| Sep 30, 2024 | -38.22 Mn |
| Jun 30, 2024 | 77.24 Mn |
| Jun 30, 2024 | 77.24 Mn |
| Mar 31, 2024 | -23.10 Mn |
| Mar 31, 2024 | -23.10 Mn |
| Dec 31, 2023 | 21.70 Mn |
| Dec 31, 2023 | 21.70 Mn |
| Sep 30, 2023 | -30.47 Mn |
| Sep 30, 2023 | -30.47 Mn |