Replimune (REPL) Net Cash Flow (2017 - 2025)

Replimune's (REPL) quarterly Net Cash Flow came in at $19.6 million in Q4 2025, down 66.69% year-on-year from $58.9 million in Q4 2024, and up 497.87% quarter-over-quarter from $3.3 million in Q3 2025.

Replimune (REPL) Net Cash Flow (2017 - 2025) Analysis & Trends

Replimune has disclosed Net Cash Flow across 9 years of filings, most recently posting $19.6 million for Q4 2025.

  • Net Cash Flow for Q4 2025 came in at $19.6 million, down 66.69% year-over-year; the trailing twelve-month figure through Dec 2025 was -$50.8 million (down 167.89% YoY), and the FY2025 annual result was $36.4 million, up 150.5% from the prior year.
  • Net Cash Flow came in at $19.6 million for Q4 2025 at Replimune, up from $3.3 million in the prior quarter.
  • In the past five years, Net Cash Flow ranged from a high of $117.7 million in Q4 2022 to a low of -$141.6 million in Q1 2021.
  • The 5-year median for Net Cash Flow is -$24.4 million (2022), against an average of -$10.2 million.
  • Across the five-year window, Net Cash Flow tumbled 4081.16% in 2021 and jumped 523.56% in 2022, its largest moves.
  • Replimune's Net Cash Flow stood at -$27.8 million in 2021, then surged by 523.56% to $117.7 million in 2022, then plunged by 81.57% to $21.7 million in 2023, then soared by 171.38% to $58.9 million in 2024, then tumbled by 66.69% to $19.6 million in 2025.
  • The last three Net Cash Flow figures came in at $19.6 million (Q4 2025), $3.3 million (Q3 2025), and -$12.1 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Cash Flow (Qtr)
1 Alterity Therapeutics 762,369.55 Bn 762,369.51 Bn - -
2 Belite Bio 55,096.00 Bn 55,096.00 Bn - -
3 Quantum Biopharma 17,755.80 Bn 17,755.79 Bn - 2.44 Mn
4 Legend Biotech 3,486.00 Bn 3,485.71 Bn 242.10 Mn 625.70 Mn
5 Akari Therapeutics 1,737.42 Bn 1,737.41 Bn - -2.44 Mn
6 Evaxion A 1,551.28 Bn 1,551.26 Bn - -
7 Psyence Biomedical 227.32 Bn 227.31 Bn - -
8 Vertex Pharmaceuticals 110.84 Bn 103.59 Bn 2.59 Bn 457.40 Mn
9 Abivax 91.71 Bn 91.71 Bn - 664,983.53
10 Replimune 780.01 Mn 510.88 Mn - 19.62 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 19.62 Mn
Dec 31, 2025 19.62 Mn
Sep 30, 2025 3.28 Mn
Sep 30, 2025 3.28 Mn
Jun 30, 2025 -12.13 Mn
Jun 30, 2025 -12.13 Mn
Mar 31, 2025 -61.56 Mn
Mar 31, 2025 -61.56 Mn
Dec 31, 2024 58.90 Mn
Dec 31, 2024 58.90 Mn
Sep 30, 2024 -38.22 Mn
Sep 30, 2024 -38.22 Mn
Jun 30, 2024 77.24 Mn
Jun 30, 2024 77.24 Mn
Mar 31, 2024 -23.10 Mn
Mar 31, 2024 -23.10 Mn
Dec 31, 2023 21.70 Mn
Dec 31, 2023 21.70 Mn
Sep 30, 2023 -30.47 Mn
Sep 30, 2023 -30.47 Mn