Replimune Group, Inc. (REPL) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

0Shares Outstanding

20,451,774Shares held by institutions

$147,048,255Value of institutional holdings

91.01%Institutional ownership %

-2.20%Shares Changed QoQ

172No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Replimune Group, Inc. (NASDAQ:REPL) showed up in the 13F filings of 162 institutional investors as of December 2025.

These investors held 78.9% of outstanding shares in December 2025, down from 91.5% in September 2025.
They increased total shares held in Replimune by 9.98% from last quarter, and the number of investors in REPL increased 5.19% annually.
Of these 162 funds, 93 grew their exposure to Replimune, 52 cut back, and 17 maintained positions.
Altogether, these fund groups held 72.73Mn shares in REPL by December 2025, up by 6.6Mn shares quarter on quarter, and down 6.95Mn shares year over year.
BAKER BROS. ADVISORS LP holds the largest position in REPL at 11.05Mn shares as of December 31, 2025, or 11.98% of shares outstanding.
The largest buyers of Replimune for the quarter ending December 2025 were D. E. Shaw & Co., Inc. (2.17Mn), ADAGE CAPITAL PARTNERS GP, L.L.C. (1.81Mn), FMR LLC (1.62Mn), ADAR1 Capital Management, LLC (1.5Mn), Commodore Capital LP (1.42Mn).
Leading sellers of Replimune shares for the quarter ending December 2025 were Point72 Asset Management, L.P. (3.56Mn), BALYASNY ASSET MANAGEMENT L.P. (2.6Mn), Boxer Capital Management, LLC (1.35Mn), FCPM III SERVICES B.V. (1.35Mn), MILLENNIUM MANAGEMENT LLC (755.18K).
Per Business Quant, the top 10 investors in REPL for the quarter ending December 2025 include BAKER BROS. ADVISORS LP (11.05Mn), RTW INVESTMENTS, LP (7.14Mn), BlackRock, Inc. (6.07Mn), VANGUARD GROUP INC (3.78Mn), State Street Corp (3.69Mn), FMR LLC (2.98Mn), FCPM III SERVICES B.V. (2.81Mn), D. E. Shaw & Co., Inc. (2.58Mn), ADAR1 Capital Management, LLC (2.48Mn), Toronto Dominion Bank (2.23Mn).

162 Institutional Holders

20,451,774 Total Shares Held

Rows:

Download Data

Owner Name	Date	Change (QoQ)	Change (%)	Value (USD)
BlackRock, Inc.	31 Dec, 2025	293,737	5.09%	$0.00
BAKER BROS. ADVISORS LP	31 Dec, 2025	0	0.00%	$0.00
FCPM III SERVICES B.V.	31 Dec, 2025	-1,350,000	-32.46%	$0.00
Barclays Plc	31 Dec, 2025	-322,168	-52.44%	$0.00
RTW INVESTMENTS, LP	31 Dec, 2025	744,620	11.64%	$0.00
ADAR1 Capital Management, LLC	31 Dec, 2025	1,503,750	153.62%	$0.00
VANGUARD GROUP INC	31 Dec, 2025	296,803	8.53%	$0.00
Erste Asset Management GmbH	31 Dec, 2025	490,000	30.06%	$0.00
State Street Corp	31 Dec, 2025	768,982	26.30%	$0.00
Commodore Capital LP	31 Dec, 2025	1,425,000	0.00%	$0.00
FMR LLC	31 Dec, 2025	1,620,501	119.06%	$0.00
Rosalind Advisors, Inc.	31 Dec, 2025	1,410,497	0.00%	$0.00
D. E. Shaw & Co., Inc.	31 Dec, 2025	2,171,547	538.18%	$0.00
Boxer Capital Management, LLC	31 Dec, 2025	-1,350,000	-64.29%	$0.00
Toronto Dominion Bank	31 Dec, 2025	857,475	62.50%	$0.00
UBS Group AG	31 Dec, 2025	-297,317	-32.98%	$0.00
ADAGE CAPITAL PARTNERS GP, L.L.C.	31 Dec, 2025	1,807,368	0.00%	$0.00
NAN FUNG TRINITY (HK) Ltd	31 Dec, 2025	110,000	23.63%	$0.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	54,746	3.23%	$0.00
Woodline Partners LP	31 Dec, 2025	-285,000	-33.29%	$0.00

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