Replimune Group, Inc. (REPL) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

92,116,883Shares Outstanding

11,559,068Shares held by institutions

$83,918,834Value of institutional holdings

79.19%Institutional ownership %

8.45%Shares Changed QoQ

163No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

A total of 163 institutions have reported a stake in Replimune Group, Inc. (NASDAQ:REPL) as of December 2025, according to recent 13F filings with the SEC.

The percentage of Replimune owned by institutions changed from 95.6% in September 2025 to 79.2% in December 2025, marking a slight down trend.
Institutional share ownership changed by 8.45% QoQ, while the number of institutional owners saw an increase of 5.84% YoY.
The latest 13F cycle for Replimune reveals that of 163 total investors, 93 funds grew their exposure, whereas 53 reduced theirs and 17 made no changes.
This class of investors increased its holdings in Replimune to 72.95Mn shares for the 13F-cycle ending December 2025, up by 5.69Mn shares quarter on quarter, and down 4.57Mn shares year over year.
BAKER BROS. ADVISORS LP continues to be the largest institutional holder of Replimune as of December 31, 2025, with a position of 11.05Mn shares, representing 11.99% of the company's outstanding stock.
Among the most significant buyers of Replimune during December 2025 were D. E. Shaw & Co., Inc. (2.17Mn), ADAGE CAPITAL PARTNERS GP, L.L.C. (1.81Mn), FMR LLC (1.62Mn), Commodore Capital LP (1.43Mn), Rosalind Advisors, Inc. (1.41Mn).
Leading sellers of Replimune stock in December 2025 included Point72 Asset Management, L.P. (3.56Mn), BALYASNY ASSET MANAGEMENT L.P. (2.60Mn), FCPM III SERVICES B.V. (1.35Mn), MILLENNIUM MANAGEMENT LLC (905.18K), MORGAN STANLEY (560.63K).
The top 10 institutional holders of Replimune for the quarter ending December 2025 included BAKER BROS. ADVISORS LP (11.05Mn), RTW INVESTMENTS, LP (7.14Mn), BlackRock, Inc. (6.07Mn), VANGUARD GROUP INC (3.78Mn), STATE STREET CORP (3.69Mn), FMR LLC (2.98Mn), FCPM III SERVICES B.V. (2.81Mn), D. E. Shaw & Co., Inc. (2.58Mn), TORONTO DOMINION BANK (2.23Mn), Erste Asset Management GmbH (2.12Mn).

163 Institutional Holders

11,559,068 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
BAKER BROS. ADVISORS LP	31 Dec, 2025	11,045,336	0	0.00%	$107,360,666.00
RTW INVESTMENTS, LP	31 Dec, 2025	7,140,352	744,620	11.64%	$69,404,221.00
BlackRock, Inc.	31 Dec, 2025	6,069,633	293,737	5.09%	$58,996,834.00
VANGUARD GROUP INC	31 Dec, 2025	3,776,198	296,803	8.53%	$36,704,645.00
STATE STREET CORP	31 Dec, 2025	3,693,107	768,982	26.30%	$35,897,000.00
FMR LLC	31 Dec, 2025	2,981,580	1,620,501	119.06%	$28,980,955.00
FCPM III SERVICES B.V.	31 Dec, 2025	2,808,368	-1,350,000	-32.46%	$27,297,337.00
D. E. Shaw & Co., Inc.	31 Dec, 2025	2,575,042	2,171,547	538.18%	$25,029,408.00
TORONTO DOMINION BANK	31 Dec, 2025	2,229,527	857,475	62.50%	$21,671,002.00
Erste Asset Management GmbH	31 Dec, 2025	2,120,000	490,000	30.06%	$20,619,200.00
ADAGE CAPITAL PARTNERS GP, L.L.C.	31 Dec, 2025	1,807,368	1,807,368	0.00%	$17,567,617.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	1,750,194	54,746	3.23%	$17,015,933.00
Commodore Capital LP	31 Dec, 2025	1,425,000	1,425,000	0.00%	$13,851,000.00
Rosalind Advisors, Inc.	31 Dec, 2025	1,410,497	1,410,497	0.00%	$13,710,031.00
ADAR1 Capital Management, LLC	31 Dec, 2025	1,266,322	237,428	23.08%	$12,308,650.00
Caption Management, LLC	31 Dec, 2025	1,213,570	191,370	18.72%	$11,795,900.00
DIMENSIONAL FUND ADVISORS LP	31 Dec, 2025	1,119,357	-132,144	-10.56%	$10,880,742.00
Redmile Group, LLC	31 Dec, 2025	1,099,756	563,938	105.25%	$10,689,628.00
MILLENNIUM MANAGEMENT LLC	31 Dec, 2025	984,562	-905,183	-47.90%	$9,569,943.00
JPMORGAN CHASE & CO	31 Dec, 2025	925,173	887,157	2,333.64%	$8,992,681.00

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