Replimune Group, Inc. (REPL) Institutional Ownership

Institutions by Trading Activity

92,187,581Shares Outstanding

73,383,703Shares held by institutions

$377,926,070Value of institutional holdings

79.60%Institutional ownership %

9.96%Shares Changed QoQ

162No. of institutional investors

Replimune Group, Inc. (NASDAQ:REPL) showed up in the 13F filings of 162 institutional investors as of December 2025.

Collectively, these holders controlled 78.9% of Replimune's outstanding shares in December 2025, down from 91.5% in September 2025.
They increased total shares held in REPL by 9.98% quarter over quarter, and investors in Replimune increased 5.19% from a year ago.
Of these 162 holders, 93 added to their stakes in Replimune, 52 trimmed positions, and 17 made no changes.
Institutional investors collectively held 72.73Mn shares in Replimune as of December 2025, up by 6.6Mn shares quarter on quarter, and down 6.95Mn shares year over year.
SG Americas Securities, LLC holds the largest position in REPL at 151.67K shares as of December 31, 2025, or 0.16% of shares outstanding.
The biggest buyers of Replimune for the quarter ending December 2025 included SG Americas Securities, LLC (79.72K), TEMA ETFS LLC (55.6K), E Fund Management Co., Ltd. (14.89K), GAMMA Investing LLC (1.94K), GF FUND MANAGEMENT CO. LTD. (212).
The largest sales of REPL for the quarter ending December 2025 came from Sterling Capital Management LLC (1.62K), Farther Finance Advisors, LLC (372).
Replimune's 10 largest shareholders as of December 2025 include SG Americas Securities, LLC (151.67K), TEMA ETFS LLC (106.88K), E Fund Management Co., Ltd. (14.89K), Sterling Capital Management LLC (2.48K), GAMMA Investing LLC (2.43K), SIGNATUREFD, LLC (2.36K), GF FUND MANAGEMENT CO. LTD. (1.75K), Farther Finance Advisors, LLC (1.68K), True Wealth Design, LLC (117), Root Financial Partners, LLC (32) per Business Quant data.

73,383,703 Total Shares Held

Rows:

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
BAKER BROS. ADVISORS LP	31 Mar, 2026	11,045,336	0	0.00%	$84,496,820.00
BAKER BROS. ADVISORS LP	31 Mar, 2026	11,045,336	0	0.00%	$107,360,666.00
PRICE T ROWE ASSOCIATES INC /MD/	31 Mar, 2026	8,121,433	8,121,433	0.00%	$62,130.00
RTW INVESTMENTS, LP	31 Mar, 2026	7,356,916	216,564	3.03%	$56,280,407.00
RTW INVESTMENTS, LP	31 Mar, 2026	7,140,352	744,620	11.64%	$69,404,221.00
BlackRock, Inc.	31 Mar, 2026	6,239,239	169,606	2.79%	$47,730,179.00
BlackRock, Inc.	31 Mar, 2026	6,069,633	293,737	5.09%	$58,996,834.00
SUVRETTA CAPITAL MANAGEMENT, LLC	31 Mar, 2026	4,221,836	4,185,798	11,614.96%	$32,297,045.00
State Street Corp	31 Mar, 2026	3,782,237	89,130	2.41%	$28,934,113.00
VANGUARD GROUP INC	31 Mar, 2026	3,776,198	296,803	8.53%	$36,704,645.00
State Street Corp	31 Mar, 2026	3,693,107	768,982	26.30%	$35,897,000.00
FMR LLC	31 Mar, 2026	2,981,580	1,620,501	119.06%	$28,980,955.00
FCPM III SERVICES B.V.	31 Mar, 2026	2,808,368	0	0.00%	$21,484,015.00
FCPM III SERVICES B.V.	31 Mar, 2026	2,808,368	-1,350,000	-32.46%	$27,297,337.00
VANGUARD CAPITAL MANAGEMENT LLC	31 Mar, 2026	2,759,120	2,759,120	0.00%	$21,107,268.00
D. E. Shaw & Co., Inc.	31 Mar, 2026	2,575,042	2,171,547	538.18%	$25,029,408.00
ADAR1 Capital Management, LLC	31 Mar, 2026	2,482,644	1,503,750	153.62%	$24,131,300.00
D. E. Shaw & Co., Inc.	31 Mar, 2026	2,336,528	-238,514	-9.26%	$17,874,440.00
Goldman Sachs Group Inc	31 Mar, 2026	2,277,276	961,084	73.02%	$17,421,161.00
Toronto Dominion Bank	31 Mar, 2026	2,229,527	857,475	62.50%	$21,671,002.00

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