Replimune Group, Inc. (REPL) Institutional Ownership

Ownership Summary

Replimune Group, Inc. (NASDAQ:REPL) appears in 162 institutional 13F filings for the quarter ending December 2025.

• Collectively, these holders controlled 78.9% of Replimune's outstanding shares in December 2025, down from 91.5% in September 2025.
• Their total shares held in REPL increased 9.98% from the prior quarter, while the number of investors in Replimune increased 5.19% year over year.
• During the quarter, 93 of these 162 funds increased positions in REPL, 52 reduced exposure, and 17 held steady.
• The aggregate institutional position in Replimune amounted to 72.73Mn shares as of December 2025, up by 6.6Mn shares quarter on quarter, and down 6.95Mn shares year over year.
• As of December 31, 2025, the biggest holder of Replimune is BAKER BROS. ADVISORS LP at 11.05Mn shares, representing 11.98% of shares outstanding.
• The biggest buyers of Replimune for the quarter ending December 2025 included PRICE T ROWE ASSOCIATES INC /MD/ (8.12Mn), SUVRETTA CAPITAL MANAGEMENT, LLC (4.19Mn), VANGUARD CAPITAL MANAGEMENT LLC (2.76Mn), EcoR1 Capital, LLC (1.0Mn), Goldman Sachs Group Inc (961.08K).
• Top sellers of REPL stock for the quarter ending December 2025 included ADAGE CAPITAL PARTNERS GP, L.L.C. (1.5Mn), FMR LLC (936.09K), ADAR1 Capital Management, LLC (899.66K), Toronto Dominion Bank (638.5K), MILLENNIUM MANAGEMENT LLC (533.73K).
• Business Quant data shows the 10 biggest positions in Replimune as of December 2025 are held by BAKER BROS. ADVISORS LP (11.05Mn), PRICE T ROWE ASSOCIATES INC /MD/ (8.12Mn), RTW INVESTMENTS, LP (7.36Mn), BlackRock, Inc. (6.24Mn), SUVRETTA CAPITAL MANAGEMENT, LLC (4.22Mn), State Street Corp (3.78Mn), FCPM III SERVICES B.V. (2.81Mn), VANGUARD CAPITAL MANAGEMENT LLC (2.76Mn), D. E. Shaw & Co., Inc. (2.34Mn), Goldman Sachs Group Inc (2.28Mn).