Replimune Group, Inc. (REPL) Institutional Ownership

Ownership Summary

Replimune Group, Inc. (NASDAQ:REPL) appears in 162 institutional 13F filings for the quarter ending December 2025.

• These investors held 78.9% of outstanding shares in December 2025, down from 91.5% in September 2025.
• They increased total shares held in REPL by 9.98% quarter over quarter, and investors in Replimune increased 5.19% from a year ago.
• Activity in REPL broke down as 93 buyers, 52 sellers, and 17 unchanged among 162 total holders.
• In total, institutional investors held 72.73Mn shares in Replimune as of December 2025, up by 6.6Mn shares quarter on quarter, and down 6.95Mn shares year over year.
• As of December 31, 2025, BAKER BROS. ADVISORS LP held the largest stake in Replimune with 11.05Mn shares, accounting for 11.98% of total shares outstanding.
• The most significant purchases of REPL for the quarter ending December 2025 came from PRICE T ROWE ASSOCIATES INC /MD/ (8.12Mn), SUVRETTA CAPITAL MANAGEMENT, LLC (4.19Mn), VANGUARD CAPITAL MANAGEMENT LLC (2.76Mn), EcoR1 Capital, LLC (1.0Mn), Goldman Sachs Group Inc (961.08K).
• The largest sellers of Replimune for the quarter ending December 2025 were ADAGE CAPITAL PARTNERS GP, L.L.C. (1.5Mn), FMR LLC (936.09K), ADAR1 Capital Management, LLC (899.66K), Toronto Dominion Bank (638.5K), MILLENNIUM MANAGEMENT LLC (533.73K).
• Business Quant data shows the 10 biggest positions in Replimune as of December 2025 are held by BAKER BROS. ADVISORS LP (11.05Mn), PRICE T ROWE ASSOCIATES INC /MD/ (8.12Mn), RTW INVESTMENTS, LP (7.36Mn), BlackRock, Inc. (6.24Mn), SUVRETTA CAPITAL MANAGEMENT, LLC (4.22Mn), State Street Corp (3.78Mn), FCPM III SERVICES B.V. (2.81Mn), VANGUARD CAPITAL MANAGEMENT LLC (2.76Mn), D. E. Shaw & Co., Inc. (2.34Mn), Goldman Sachs Group Inc (2.28Mn).