Replimune Group, Inc. (REPL) Institutional Ownership

Institutions by Trading Activity

92,187,581Shares Outstanding

73,383,703Shares held by institutions

$190,063,791Value of institutional holdings

79.60%Institutional ownership %

9.96%Shares Changed QoQ

162No. of institutional investors

Replimune Group, Inc. (NASDAQ:REPL) has 162 institutional investors that have filed 13F reports for the period ending December 2025.

These investors held 78.9% of outstanding shares in December 2025, down from 91.5% in September 2025.
Their total shares held in REPL increased 9.98% from the prior quarter, while the number of investors in Replimune increased 5.19% year over year.
Of these 162 funds, 93 grew their exposure to Replimune, 52 cut back, and 17 maintained positions.
The aggregate institutional position in Replimune amounted to 72.73Mn shares as of December 2025, up by 6.6Mn shares quarter on quarter, and down 6.95Mn shares year over year.
SG Americas Securities, LLC holds the largest position in REPL at 151.67K shares as of December 31, 2025, or 0.16% of shares outstanding.
The most significant purchases of REPL for the quarter ending December 2025 came from SG Americas Securities, LLC (79.72K), TEMA ETFS LLC (55.6K), E Fund Management Co., Ltd. (14.89K), GAMMA Investing LLC (1.94K), GF FUND MANAGEMENT CO. LTD. (212).
The biggest sellers of Replimune for the quarter ending December 2025 included Sterling Capital Management LLC (1.62K), Farther Finance Advisors, LLC (372).
According to Business Quant data, leading holders of REPL for December 2025 are SG Americas Securities, LLC (151.67K), TEMA ETFS LLC (106.88K), E Fund Management Co., Ltd. (14.89K), Sterling Capital Management LLC (2.48K), GAMMA Investing LLC (2.43K), SIGNATUREFD, LLC (2.36K), GF FUND MANAGEMENT CO. LTD. (1.75K), Farther Finance Advisors, LLC (1.68K), True Wealth Design, LLC (117), Root Financial Partners, LLC (32).

73,383,703 Total Shares Held

Rows:

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
BAKER BROS. ADVISORS LP	31 Dec, 2025	11,045,336	0	0.00%	$107,360,666.00
RTW INVESTMENTS, LP	31 Dec, 2025	7,140,352	744,620	11.64%	$69,404,221.00
BlackRock, Inc.	31 Dec, 2025	6,069,633	293,737	5.09%	$58,996,834.00
VANGUARD GROUP INC	31 Dec, 2025	3,776,198	296,803	8.53%	$36,704,645.00
State Street Corp	31 Dec, 2025	3,693,107	768,982	26.30%	$35,897,000.00
FMR LLC	31 Dec, 2025	2,981,580	1,620,501	119.06%	$28,980,955.00
FCPM III SERVICES B.V.	31 Dec, 2025	2,808,368	-1,350,000	-32.46%	$27,297,337.00
D. E. Shaw & Co., Inc.	31 Dec, 2025	2,575,042	2,171,547	538.18%	$25,029,408.00
ADAR1 Capital Management, LLC	31 Dec, 2025	2,482,644	1,503,750	153.62%	$24,131,300.00
Toronto Dominion Bank	31 Dec, 2025	2,229,527	857,475	62.50%	$21,671,002.00
Erste Asset Management GmbH	31 Dec, 2025	2,120,000	490,000	30.06%	$20,619,200.00
ADAGE CAPITAL PARTNERS GP, L.L.C.	31 Dec, 2025	1,807,368	1,807,368	0.00%	$17,567,617.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	1,750,194	54,746	3.23%	$17,015,933.00
Commodore Capital LP	31 Dec, 2025	1,425,000	1,425,000	0.00%	$13,851,000.00
Rosalind Advisors, Inc.	31 Dec, 2025	1,410,497	1,410,497	0.00%	$13,710,031.00
Goldman Sachs Group Inc	31 Dec, 2025	1,316,192	181,441	15.99%	$12,793,386.00
DIMENSIONAL FUND ADVISORS LP	31 Dec, 2025	1,119,357	-132,144	-10.56%	$10,880,742.00
Redmile Group, LLC	31 Dec, 2025	1,099,756	563,938	105.25%	$10,689,628.00
Jpmorgan Chase & Co	31 Dec, 2025	925,173	849,141	1,116.82%	$8,992,681.00
MILLENNIUM MANAGEMENT LLC	31 Dec, 2025	834,562	-755,183	-47.50%	$8,111,943.00

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