Replimune (REPL) Enterprise Value (2018 - 2025)
Replimune's (REPL) quarterly Enterprise Value came in at -$269.1 million in Q4 2025, up 49.84% year-on-year from -$179.6 million in Q4 2024, and up 16.84% quarter-over-quarter from -$323.6 million in Q3 2025.
Replimune (REPL) Enterprise Value (2018 - 2025) Analysis & Trends
Replimune has disclosed Enterprise Value across 8 years of filings, most recently posting -$269.1 million for Q4 2025.
- Enterprise Value for Q4 2025 came in at -$269.1 million, up 49.84% year-over-year; the trailing twelve-month figure through Dec 2025 was -$269.1 million (up 49.84% YoY), and the FY2025 annual result was -$483.8 million, down 15.01% from the prior year.
- Enterprise Value came in at -$269.1 million for Q4 2025 at Replimune, up from -$323.6 million in the prior quarter.
- In the past five years, Enterprise Value ranged from a high of -$269.1 million in Q4 2025 to a low of -$616.4 million in Q4 2022.
- The 5-year median for Enterprise Value is -$447.1 million (2021), against an average of -$446.9 million.
- Across the five-year window, Enterprise Value tumbled 226.76% in 2021 and soared 49.84% in 2025, its largest moves.
- Replimune's Enterprise Value stood at -$420.2 million in 2021, then sank by 46.7% to -$616.4 million in 2022, then climbed by 24.34% to -$466.4 million in 2023, then fell by 15.05% to -$536.5 million in 2024, then jumped by 49.84% to -$269.1 million in 2025.
- The last three Enterprise Value figures came in at -$269.1 million (Q4 2025), -$323.6 million (Q3 2025), and -$403.3 million (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Enterprise Value (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 762,369.55 Bn | 762,369.51 Bn | - | -32.30 Mn |
| 2 | Belite Bio | 55,096.00 Bn | 55,096.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,755.80 Bn | 17,755.79 Bn | - | -4.14 Mn |
| 4 | Legend Biotech | 3,486.00 Bn | 3,485.71 Bn | 242.10 Mn | -286.70 Mn |
| 5 | Akari Therapeutics | 1,737.42 Bn | 1,737.41 Bn | - | -2.77 Mn |
| 6 | Evaxion A | 1,551.28 Bn | 1,551.26 Bn | - | -18.44 Mn |
| 7 | Psyence Biomedical | 227.32 Bn | 227.31 Bn | - | -7.20 Mn |
| 8 | Vertex Pharmaceuticals | 110.84 Bn | 103.59 Bn | 2.59 Bn | -7.25 Bn |
| 9 | Abivax | 91.71 Bn | 91.71 Bn | - | -584.73 Mn |
| 10 | Replimune | 780.01 Mn | 510.88 Mn | - | -269.14 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -269.14 Mn |
| Sep 30, 2025 | -323.64 Mn |
| Jun 30, 2025 | -403.34 Mn |
| Mar 31, 2025 | -483.80 Mn |
| Dec 31, 2024 | -536.54 Mn |
| Sep 30, 2024 | -432.06 Mn |
| Jun 30, 2024 | -469.12 Mn |
| Mar 31, 2024 | -420.67 Mn |
| Dec 31, 2023 | -466.35 Mn |
| Sep 30, 2023 | -496.76 Mn |
| Jun 30, 2023 | -539.10 Mn |
| Mar 31, 2023 | -558.30 Mn |
| Dec 31, 2022 | -616.37 Mn |
| Sep 30, 2022 | -371.82 Mn |
| Jun 30, 2022 | -395.08 Mn |
| Mar 31, 2022 | -364.81 Mn |
| Dec 31, 2021 | -420.17 Mn |
| Sep 30, 2021 | -435.77 Mn |
| Jun 30, 2021 | -458.33 Mn |
| Mar 31, 2021 | -476.30 Mn |