Replimune (REPL) Enterprise Value (2018 - 2025)

Replimune's (REPL) quarterly Enterprise Value came in at -$269.1 million in Q4 2025, up 49.84% year-on-year from -$179.6 million in Q4 2024, and up 16.84% quarter-over-quarter from -$323.6 million in Q3 2025.

Replimune (REPL) Enterprise Value (2018 - 2025) Analysis & Trends

Replimune has disclosed Enterprise Value across 8 years of filings, most recently posting -$269.1 million for Q4 2025.

  • Enterprise Value for Q4 2025 came in at -$269.1 million, up 49.84% year-over-year; the trailing twelve-month figure through Dec 2025 was -$269.1 million (up 49.84% YoY), and the FY2025 annual result was -$483.8 million, down 15.01% from the prior year.
  • Enterprise Value came in at -$269.1 million for Q4 2025 at Replimune, up from -$323.6 million in the prior quarter.
  • In the past five years, Enterprise Value ranged from a high of -$269.1 million in Q4 2025 to a low of -$616.4 million in Q4 2022.
  • The 5-year median for Enterprise Value is -$447.1 million (2021), against an average of -$446.9 million.
  • Across the five-year window, Enterprise Value tumbled 226.76% in 2021 and soared 49.84% in 2025, its largest moves.
  • Replimune's Enterprise Value stood at -$420.2 million in 2021, then sank by 46.7% to -$616.4 million in 2022, then climbed by 24.34% to -$466.4 million in 2023, then fell by 15.05% to -$536.5 million in 2024, then jumped by 49.84% to -$269.1 million in 2025.
  • The last three Enterprise Value figures came in at -$269.1 million (Q4 2025), -$323.6 million (Q3 2025), and -$403.3 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Alterity Therapeutics 762,369.55 Bn 762,369.51 Bn - -32.30 Mn
2 Belite Bio 55,096.00 Bn 55,096.00 Bn - -
3 Quantum Biopharma 17,755.80 Bn 17,755.79 Bn - -4.14 Mn
4 Legend Biotech 3,486.00 Bn 3,485.71 Bn 242.10 Mn -286.70 Mn
5 Akari Therapeutics 1,737.42 Bn 1,737.41 Bn - -2.77 Mn
6 Evaxion A 1,551.28 Bn 1,551.26 Bn - -18.44 Mn
7 Psyence Biomedical 227.32 Bn 227.31 Bn - -7.20 Mn
8 Vertex Pharmaceuticals 110.84 Bn 103.59 Bn 2.59 Bn -7.25 Bn
9 Abivax 91.71 Bn 91.71 Bn - -584.73 Mn
10 Replimune 780.01 Mn 510.88 Mn - -269.14 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -269.14 Mn
Sep 30, 2025 -323.64 Mn
Jun 30, 2025 -403.34 Mn
Mar 31, 2025 -483.80 Mn
Dec 31, 2024 -536.54 Mn
Sep 30, 2024 -432.06 Mn
Jun 30, 2024 -469.12 Mn
Mar 31, 2024 -420.67 Mn
Dec 31, 2023 -466.35 Mn
Sep 30, 2023 -496.76 Mn
Jun 30, 2023 -539.10 Mn
Mar 31, 2023 -558.30 Mn
Dec 31, 2022 -616.37 Mn
Sep 30, 2022 -371.82 Mn
Jun 30, 2022 -395.08 Mn
Mar 31, 2022 -364.81 Mn
Dec 31, 2021 -420.17 Mn
Sep 30, 2021 -435.77 Mn
Jun 30, 2021 -458.33 Mn
Mar 31, 2021 -476.30 Mn