Replimune (REPL) Change in Cash (2017 - 2025)
Replimune's (REPL) quarterly Change in Cash came in at $20.7 million in Q4 2025, down 64.85% year-on-year from $58.7 million in Q4 2024, and up 319.5% quarter-over-quarter from $4.9 million in Q3 2025.
Replimune (REPL) Change in Cash (2017 - 2025) Analysis & Trends
Replimune has disclosed Change in Cash across 9 years of filings, most recently posting $20.7 million for Q4 2025.
- Change in Cash for Q4 2025 came in at $20.7 million, down 64.85% year-over-year; the trailing twelve-month figure through Dec 2025 was -$49.3 million (down 166.04% YoY), and the FY2025 annual result was $36.7 million, up 150.87% from the prior year.
- Change in Cash came in at $20.7 million for Q4 2025 at Replimune, up from $4.9 million in the prior quarter.
- In the past five years, Change in Cash ranged from a high of $117.7 million in Q4 2022 to a low of -$142.0 million in Q1 2021.
- The 5-year median for Change in Cash is -$23.2 million (2022), against an average of -$10.1 million.
- Across the five-year window, Change in Cash sank 3953.6% in 2021 and soared 525.14% in 2022, its largest moves.
- Replimune's Change in Cash stood at -$27.7 million in 2021, then jumped by 525.14% to $117.7 million in 2022, then slumped by 81.59% to $21.7 million in 2023, then surged by 171.02% to $58.7 million in 2024, then sank by 64.85% to $20.7 million in 2025.
- The last three Change in Cash figures came in at $20.7 million (Q4 2025), $4.9 million (Q3 2025), and -$13.7 million (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Change in Cash (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 762,369.55 Bn | 762,369.51 Bn | - | - |
| 2 | Belite Bio | 55,096.00 Bn | 55,096.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,755.80 Bn | 17,755.79 Bn | - | 2.44 Mn |
| 4 | Legend Biotech | 3,486.00 Bn | 3,485.71 Bn | 242.10 Mn | 623.00 Mn |
| 5 | Akari Therapeutics | 1,737.42 Bn | 1,737.41 Bn | - | -2.44 Mn |
| 6 | Evaxion A | 1,551.28 Bn | 1,551.26 Bn | - | - |
| 7 | Psyence Biomedical | 227.32 Bn | 227.31 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 110.84 Bn | 103.59 Bn | 2.59 Bn | 417.10 Mn |
| 9 | Abivax | 91.71 Bn | 91.71 Bn | - | -45.97 Mn |
| 10 | Replimune | 780.01 Mn | 510.88 Mn | - | 20.65 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | 20.65 Mn |
| Sep 30, 2025 | 4.92 Mn |
| Jun 30, 2025 | -13.74 Mn |
| Mar 31, 2025 | -61.12 Mn |
| Dec 31, 2024 | 58.75 Mn |
| Sep 30, 2024 | -38.16 Mn |
| Jun 30, 2024 | 77.20 Mn |
| Mar 31, 2024 | -23.15 Mn |
| Dec 31, 2023 | 21.68 Mn |
| Sep 30, 2023 | -30.49 Mn |
| Jun 30, 2023 | -40.11 Mn |
| Mar 31, 2023 | -60.08 Mn |
| Dec 31, 2022 | 117.74 Mn |
| Sep 30, 2022 | -23.32 Mn |
| Jun 30, 2022 | 6.30 Mn |
| Mar 31, 2022 | -26.33 Mn |
| Dec 31, 2021 | -27.69 Mn |
| Sep 30, 2021 | -32.56 Mn |
| Jun 30, 2021 | 10.01 Mn |
| Mar 31, 2021 | -141.96 Mn |