Replimune (REPL) Change in Cash (2017 - 2025)

Replimune's (REPL) quarterly Change in Cash came in at $20.7 million in Q4 2025, down 64.85% year-on-year from $58.7 million in Q4 2024, and up 319.5% quarter-over-quarter from $4.9 million in Q3 2025.

Replimune (REPL) Change in Cash (2017 - 2025) Analysis & Trends

Replimune has disclosed Change in Cash across 9 years of filings, most recently posting $20.7 million for Q4 2025.

  • Change in Cash for Q4 2025 came in at $20.7 million, down 64.85% year-over-year; the trailing twelve-month figure through Dec 2025 was -$49.3 million (down 166.04% YoY), and the FY2025 annual result was $36.7 million, up 150.87% from the prior year.
  • Change in Cash came in at $20.7 million for Q4 2025 at Replimune, up from $4.9 million in the prior quarter.
  • In the past five years, Change in Cash ranged from a high of $117.7 million in Q4 2022 to a low of -$142.0 million in Q1 2021.
  • The 5-year median for Change in Cash is -$23.2 million (2022), against an average of -$10.1 million.
  • Across the five-year window, Change in Cash sank 3953.6% in 2021 and soared 525.14% in 2022, its largest moves.
  • Replimune's Change in Cash stood at -$27.7 million in 2021, then jumped by 525.14% to $117.7 million in 2022, then slumped by 81.59% to $21.7 million in 2023, then surged by 171.02% to $58.7 million in 2024, then sank by 64.85% to $20.7 million in 2025.
  • The last three Change in Cash figures came in at $20.7 million (Q4 2025), $4.9 million (Q3 2025), and -$13.7 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Change in Cash (Qtr)
1 Alterity Therapeutics 762,369.55 Bn 762,369.51 Bn - -
2 Belite Bio 55,096.00 Bn 55,096.00 Bn - -
3 Quantum Biopharma 17,755.80 Bn 17,755.79 Bn - 2.44 Mn
4 Legend Biotech 3,486.00 Bn 3,485.71 Bn 242.10 Mn 623.00 Mn
5 Akari Therapeutics 1,737.42 Bn 1,737.41 Bn - -2.44 Mn
6 Evaxion A 1,551.28 Bn 1,551.26 Bn - -
7 Psyence Biomedical 227.32 Bn 227.31 Bn - -
8 Vertex Pharmaceuticals 110.84 Bn 103.59 Bn 2.59 Bn 417.10 Mn
9 Abivax 91.71 Bn 91.71 Bn - -45.97 Mn
10 Replimune 780.01 Mn 510.88 Mn - 20.65 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 20.65 Mn
Sep 30, 2025 4.92 Mn
Jun 30, 2025 -13.74 Mn
Mar 31, 2025 -61.12 Mn
Dec 31, 2024 58.75 Mn
Sep 30, 2024 -38.16 Mn
Jun 30, 2024 77.20 Mn
Mar 31, 2024 -23.15 Mn
Dec 31, 2023 21.68 Mn
Sep 30, 2023 -30.49 Mn
Jun 30, 2023 -40.11 Mn
Mar 31, 2023 -60.08 Mn
Dec 31, 2022 117.74 Mn
Sep 30, 2022 -23.32 Mn
Jun 30, 2022 6.30 Mn
Mar 31, 2022 -26.33 Mn
Dec 31, 2021 -27.69 Mn
Sep 30, 2021 -32.56 Mn
Jun 30, 2021 10.01 Mn
Mar 31, 2021 -141.96 Mn