Replimune (REPL) Cash from Operations (2017 - 2025)

Replimune's (REPL) quarterly Cash from Operations came in at 65955000.0 in Q4 2025, down 30.06% year-on-year from 94296070.45 in Q4 2024, and up 18.79% quarter-over-quarter from 81212000.0 in Q3 2025.

Replimune (REPL) Cash from Operations (2017 - 2025) Analysis & Trends

Replimune has disclosed Cash from Operations across 9 years of filings, most recently posting 65955000.0 for Q4 2025.

  • Cash from Operations for Q4 2025 came in at 65955000.0, down 30.06% year-over-year; the trailing twelve-month figure through Dec 2025 was 277914000.0 (down 50.48% YoY), and the FY2025 annual result was 192250000.0, down 3.66% from the prior year.
  • Cash from Operations came in at 65955000.0 for Q4 2025 at Replimune, up from 81212000.0 in the prior quarter.
  • In the past five years, Cash from Operations ranged from a high of 16128000.0 in Q1 2021 to a low of 81212000.0 in Q3 2025.
  • The 5-year median for Cash from Operations is 41114500.0 (2023), against an average of 41412900.0.
  • Across the five-year window, Cash from Operations advanced 11.36% in 2024 and sank 110.18% in 2025, its largest moves.
  • Replimune's Cash from Operations stood at 18348000.0 in 2021, then plunged by 55.82% to 28589000.0 in 2022, then plunged by 64.83% to 47123000.0 in 2023, then slipped by 7.62% to 50713000.0 in 2024, then slumped by 30.06% to 65955000.0 in 2025.
  • The last three Cash from Operations figures came in at 65955000.0 (Q4 2025), 81212000.0 (Q3 2025), and 77016000.0 (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Cash from Operations (Qtr)
1 Alterity Therapeutics 762,369.55 Bn 762,369.51 Bn - -
2 Belite Bio 55,096.00 Bn 55,096.00 Bn - -
3 Quantum Biopharma 17,755.80 Bn 17,755.79 Bn - -1.67 Mn
4 Legend Biotech 3,486.00 Bn 3,485.71 Bn 242.10 Mn -12.20 Mn
5 Akari Therapeutics 1,737.42 Bn 1,737.41 Bn - -2.49 Mn
6 Evaxion A 1,551.28 Bn 1,551.26 Bn - -
7 Psyence Biomedical 227.32 Bn 227.31 Bn - -
8 Vertex Pharmaceuticals 110.84 Bn 103.59 Bn 2.59 Bn 1.43 Bn
9 Abivax 91.71 Bn 91.71 Bn - -
10 Replimune 780.01 Mn 510.88 Mn - -65.96 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -65.96 Mn
Dec 31, 2025 -65.96 Mn
Sep 30, 2025 -81.21 Mn
Sep 30, 2025 -81.21 Mn
Jun 30, 2025 -77.02 Mn
Jun 30, 2025 -77.02 Mn
Mar 31, 2025 -53.73 Mn
Mar 31, 2025 -53.73 Mn
Dec 31, 2024 -50.71 Mn
Dec 31, 2024 -50.71 Mn
Sep 30, 2024 -38.64 Mn
Sep 30, 2024 -38.64 Mn
Jun 30, 2024 -49.17 Mn
Jun 30, 2024 -49.17 Mn
Mar 31, 2024 -46.17 Mn
Mar 31, 2024 -46.17 Mn
Dec 31, 2023 -47.12 Mn
Dec 31, 2023 -47.12 Mn
Sep 30, 2023 -43.59 Mn
Sep 30, 2023 -43.59 Mn