Replimune (REPL) Cash from Operations (2017 - 2025)
Replimune's (REPL) quarterly Cash from Operations came in at 65955000.0 in Q4 2025, down 30.06% year-on-year from 94296070.45 in Q4 2024, and up 18.79% quarter-over-quarter from 81212000.0 in Q3 2025.
Replimune (REPL) Cash from Operations (2017 - 2025) Analysis & Trends
Replimune has disclosed Cash from Operations across 9 years of filings, most recently posting 65955000.0 for Q4 2025.
- Cash from Operations for Q4 2025 came in at 65955000.0, down 30.06% year-over-year; the trailing twelve-month figure through Dec 2025 was 277914000.0 (down 50.48% YoY), and the FY2025 annual result was 192250000.0, down 3.66% from the prior year.
- Cash from Operations came in at 65955000.0 for Q4 2025 at Replimune, up from 81212000.0 in the prior quarter.
- In the past five years, Cash from Operations ranged from a high of 16128000.0 in Q1 2021 to a low of 81212000.0 in Q3 2025.
- The 5-year median for Cash from Operations is 41114500.0 (2023), against an average of 41412900.0.
- Across the five-year window, Cash from Operations advanced 11.36% in 2024 and sank 110.18% in 2025, its largest moves.
- Replimune's Cash from Operations stood at 18348000.0 in 2021, then plunged by 55.82% to 28589000.0 in 2022, then plunged by 64.83% to 47123000.0 in 2023, then slipped by 7.62% to 50713000.0 in 2024, then slumped by 30.06% to 65955000.0 in 2025.
- The last three Cash from Operations figures came in at 65955000.0 (Q4 2025), 81212000.0 (Q3 2025), and 77016000.0 (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Cash from Operations (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 762,369.55 Bn | 762,369.51 Bn | - | - |
| 2 | Belite Bio | 55,096.00 Bn | 55,096.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,755.80 Bn | 17,755.79 Bn | - | -1.67 Mn |
| 4 | Legend Biotech | 3,486.00 Bn | 3,485.71 Bn | 242.10 Mn | -12.20 Mn |
| 5 | Akari Therapeutics | 1,737.42 Bn | 1,737.41 Bn | - | -2.49 Mn |
| 6 | Evaxion A | 1,551.28 Bn | 1,551.26 Bn | - | - |
| 7 | Psyence Biomedical | 227.32 Bn | 227.31 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 110.84 Bn | 103.59 Bn | 2.59 Bn | 1.43 Bn |
| 9 | Abivax | 91.71 Bn | 91.71 Bn | - | - |
| 10 | Replimune | 780.01 Mn | 510.88 Mn | - | -65.96 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -65.96 Mn |
| Dec 31, 2025 | -65.96 Mn |
| Sep 30, 2025 | -81.21 Mn |
| Sep 30, 2025 | -81.21 Mn |
| Jun 30, 2025 | -77.02 Mn |
| Jun 30, 2025 | -77.02 Mn |
| Mar 31, 2025 | -53.73 Mn |
| Mar 31, 2025 | -53.73 Mn |
| Dec 31, 2024 | -50.71 Mn |
| Dec 31, 2024 | -50.71 Mn |
| Sep 30, 2024 | -38.64 Mn |
| Sep 30, 2024 | -38.64 Mn |
| Jun 30, 2024 | -49.17 Mn |
| Jun 30, 2024 | -49.17 Mn |
| Mar 31, 2024 | -46.17 Mn |
| Mar 31, 2024 | -46.17 Mn |
| Dec 31, 2023 | -47.12 Mn |
| Dec 31, 2023 | -47.12 Mn |
| Sep 30, 2023 | -43.59 Mn |
| Sep 30, 2023 | -43.59 Mn |