Growth Metrics

Ultragenyx Pharmaceutical (RARE) Net Margin (2016 - 2025)

Ultragenyx Pharmaceutical has reported Net Margin over the past 10 years, most recently at 62.02% for Q4 2025.

  • Quarterly Net Margin rose 1949.0% to 62.02% in Q4 2025 from the year-ago period, while the trailing twelve-month figure was 85.44% through Dec 2025, up 1635.0% year-over-year, with the annual reading at 85.44% for FY2025, 1635.0% up from the prior year.
  • Net Margin was 62.02% for Q4 2025 at Ultragenyx Pharmaceutical, up from 112.81% in the prior quarter.
  • Over five years, Net Margin peaked at 399.16% in Q4 2021 and troughed at 270.23% in Q3 2022.
  • The 5-year median for Net Margin is 124.89% (2021), against an average of 81.1%.
  • Year-over-year, Net Margin plummeted -54766bps in 2022 and then soared 53031bps in 2023.
  • A 5-year view of Net Margin shows it stood at 399.16% in 2021, then plummeted by -137bps to 148.5% in 2022, then surged by 357bps to 381.81% in 2023, then tumbled by -121bps to 81.51% in 2024, then rose by 24bps to 62.02% in 2025.
  • Per Business Quant, the three most recent readings for RARE's Net Margin are 62.02% (Q4 2025), 112.81% (Q3 2025), and 69.04% (Q2 2025).