Ultragenyx Pharmaceutical (RARE) Net Margin (2016 - 2026)

Ultragenyx Pharmaceutical's (RARE) quarterly Net Margin came in at 136.03% in Q1 2026, down 2740.0% year-on-year from 5.15% in Q1 2025, and down 130.07% on a QoQ basis from 59.13% in Q4 2025.

Ultragenyx Pharmaceutical (RARE) Net Margin (2016 - 2026) Analysis & Trends

Ultragenyx Pharmaceutical (RARE) has 11 years of Net Margin data on file, last reported at 136.03% in Q1 2026.

  • On a quarterly basis, Net Margin fell 2740.0% year-over-year to 136.03% in Q1 2026; TTM through Mar 2026 was 90.03%, a 237.0% increase from a year earlier, with the FY2025 full-year figure at 84.55%, up 1635.0% from the prior year.
  • Net Margin for Q1 2026 stood at 136.03%, down from 59.13% in the prior quarter.
  • Over the last five years, Net Margin for RARE reached as high as 59.13% in Q4 2025 and fell as low as 270.23% in Q3 2022.
  • Historically, Net Margin has averaged 133.13% across 5 years, with a median of 136.03% in 2026.
  • Across the five-year window, Net Margin sank 54766 bps in 2022 and surged 10741 bps in 2023, its largest moves.
  • Year by year, Net Margin stood at 148.5% in 2022, then jumped by 35 bps to 97.17% in 2023, then advanced by 19 bps to 78.47% in 2024, then advanced by 25 bps to 59.13% in 2025, then sank by 130 bps to 136.03% in 2026.
  • Per Business Quant data, the three most recent Net Margin figures were 136.03% in Q1 2026, 59.13% in Q4 2025, and 112.81% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Margin (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 15.02%
4 NuCana 279.75 Bn 279.75 Bn - -
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 34.53%
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 20.17%
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 30.33%
9 Revolution Medicines 37.78 Bn 37.78 Bn - -
10 Ultragenyx Pharmaceutical 2.72 Bn 2.31 Bn 106.00 Mn -136.03%

Historic Data

Download Data
DateValue
Mar 31, 2026 -136.03%
Dec 31, 2025 -59.13%
Sep 30, 2025 -112.81%
Jun 30, 2025 -69.04%
Mar 31, 2025 -108.63%
Dec 31, 2024 -78.47%
Sep 30, 2024 -95.71%
Jun 30, 2024 -89.51%
Mar 31, 2024 -156.83%
Dec 31, 2023 -97.17%
Sep 30, 2023 -162.82%
Jun 30, 2023 -147.57%
Mar 31, 2023 -163.16%
Dec 31, 2022 -148.50%
Sep 30, 2022 -270.23%
Jun 30, 2022 -177.03%
Mar 31, 2022 -190.55%
Dec 31, 2021 399.16%
Sep 30, 2021 -89.41%
Jun 30, 2021 -140.76%