Ultragenyx Pharmaceutical (RARE) Net Margin (2016 - 2026)
Ultragenyx Pharmaceutical (RARE) reported Net Margin of -42.99% for Q2 2026, up 25.87 percentage points from -68.86% a year earlier and up 93.04 percentage points from the prior quarter.
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Analysis
Ultragenyx Pharmaceutical (RARE) Net Margin (2016 - 2026) Analysis & Trends
Over the twelve months ended Jun 30, 2026, Ultragenyx Pharmaceutical's Net Margin came in at -81.70%, up 5.61 percentage points year-over-year; for FY2025, it was -85.44%, up 16.17 percentage points from FY2024.
- Net Margin has increased for three consecutive years, though with a five-year change of -16.60 percentage points (FY2020 to FY2025).
- By year, Net Margin came in at -101.61% in FY2024 (+38.25 pp), -139.86% in FY2023 (+54.84 pp), -194.71% in FY2022 (-65.50 pp) and -129.20% in FY2021 (-60.37 pp).
- The Q2 2026 figure ranks as the highest quarterly Net Margin since Q4 2020.
- Year over year, Net Margin gained in six of the last eight quarters, with an average year-over-year change of +19.06 percentage points.
- The high point for year-over-year Net Margin in five years was Q3 2023 (a gain of 107.41 percentage points); the low point was Q3 2022 (a drop of 180.82 percentage points).
- Per Business Quant data, the three quarters before Q2 2026 came in at -136.03% (Q1 2026), -62.02% (Q4 2025) and -112.81% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 645.01 Bn | 563.54 Bn | 17.26 Bn | 21.86% |
| 2 | AbbVie | 465.23 Bn | 438.39 Bn | 12.70 Bn | 21.27% |
| 3 | Merck | 368.40 Bn | 322.83 Bn | 12.21 Bn | -8.04% |
| 4 | Novartis Ag | 278.02 Bn | 233.89 Bn | 11.24 Bn | 22.61% |
| 5 | Astrazeneca | 254.57 Bn | 228.13 Bn | 12.86 Bn | 18.81% |
| 6 | Amgen | 229.02 Bn | 184.42 Bn | 7.24 Bn | 23.62% |
| 7 | Gilead Sciences | 187.74 Bn | 161.85 Bn | 6.22 Bn | -134.51% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | -1.65% |
| 9 | Vertex Pharmaceuticals | 133.45 Bn | 105.45 Bn | 2.84 Bn | 32.99% |
| 10 | Ultragenyx Pharmaceutical | 1.51 Bn | -292.70 Mn | 180.00 Mn | -42.99% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -42.99% |
| Mar 31, 2026 | -136.03% |
| Dec 31, 2025 | -62.02% |
| Sep 30, 2025 | -112.81% |
| Jun 30, 2025 | -68.86% |
| Mar 31, 2025 | -108.63% |
| Dec 31, 2024 | -80.90% |
| Sep 30, 2024 | -95.71% |
| Jun 30, 2024 | -89.51% |
| Mar 31, 2024 | -156.83% |
| Dec 31, 2023 | -97.17% |
| Sep 30, 2023 | -162.82% |
| Jun 30, 2023 | -147.57% |
| Mar 31, 2023 | -163.16% |
| Dec 31, 2022 | -146.91% |
| Sep 30, 2022 | -270.23% |
| Jun 30, 2022 | -177.03% |
| Mar 31, 2022 | -190.55% |
| Dec 31, 2021 | -146.85% |
| Sep 30, 2021 | -89.41% |
API Access
Ultragenyx Pharmaceutical Net Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=net-margin&ticker=RARE&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "net-margin", "ticker": "RARE", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=net-margin&ticker=RARE&period=max&api_key=YOUR_API_KEY");
const data = await res.json();