Pyxis Oncology PYXS
NASDAQ PYXS
$3.08 -0.04 (-1.28%)
At close: Aug 21, 2026 · 4:00 PM EDT

Pyxis Oncology (PYXS) Short-term Investments (2021 - 2026)

Pyxis Oncology (PYXS) posted quarterly Short-term Investments of $51.4 million for Q4 2025, down 52.13% year-over-year from $107.5 million in Q4 2024, and down 23.62% quarter-over-quarter from $67.3 million in Q3 2025.

Pyxis Oncology (PYXS) Short-term Investments (2021 - 2026) Analysis & Trends

Pyxis Oncology (PYXS) has reported Short-term Investments for 5 consecutive years, with $51.4 million the latest figure, recorded in Q4 2025.

  • In Q4 2025, Short-term Investments fell 52.13% year-over-year to $51.4 million; the TTM figure through Dec 2025 stood at $51.4 million (down 52.13% YoY), while the FY2025 annual figure was $51.4 million, down 52.13% from the prior year.
  • Short-term Investments declined to $51.4 million in Q4 2025 per PYXS's latest filing, from $67.3 million in the prior quarter.
  • Across five years, Short-term Investments topped out at $132.8 million in Q3 2024 and bottomed at $1.5 million in Q4 2021.
  • Historically, Short-term Investments has averaged $35.5 million across 5 years, with a median of $1.5 million in 2021.
  • Annual changes were most pronounced in 2023 — Short-term Investments jumped 7933.42% — and 2025, when it plunged 52.13%.
  • Pyxis Oncology's Short-term Investments stood at $1.5 million in 2021, then changed by 0.0% to $1.5 million in 2022, then surged by 7347.96% to $109.6 million in 2023, then dropped by 1.98% to $107.5 million in 2024, then slumped by 52.13% to $51.4 million in 2025.
  • Business Quant data shows PYXS's Short-term Investments at $51.4 million in Q4 2025, $67.3 million in Q3 2025, and $1.5 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Vertex Pharmaceuticals 139.13 Bn 131.28 Bn 2.84 Bn
2 Regeneron Pharmaceuticals 85.77 Bn 77.77 Bn 3.93 Bn
3 Argenx Se 64.64 Bn 59.46 Bn 1.37 Bn
4 Moderna 58.29 Bn 53.16 Bn 52.00 Mn
5 BeOne Medicines 41.92 Bn 36.82 Bn 1.53 Bn
6 Alnylam Pharmaceuticals 31.58 Bn 28.28 Bn 992.69 Mn
7 BioNTech SE 28.12 Bn 9.73 Bn 668.28 Mn
8 Insmed 27.39 Bn 26.22 Bn 358.27 Mn
9 Royalty Pharma 27.27 Bn 26.43 Bn -
10 Pyxis Oncology 198.37 Mn 165.38 Mn -

Historic Data

Download Data
DateValue
Jun 30, 2026 14.14 Mn
Dec 31, 2025 51.44 Mn
Sep 30, 2025 67.34 Mn
Jun 30, 2025 1.47 Mn
Mar 31, 2025 1.47 Mn
Dec 31, 2024 107.46 Mn
Sep 30, 2024 132.76 Mn
Jun 30, 2024 1.47 Mn
Mar 31, 2024 1.47 Mn
Dec 31, 2023 109.63 Mn
Sep 30, 2023 118.25 Mn
Jun 30, 2023 1.47 Mn
Mar 31, 2023 1.47 Mn
Dec 31, 2022 1.47 Mn
Sep 30, 2022 1.47 Mn
Jun 30, 2022 1.47 Mn
Mar 31, 2022 1.47 Mn
Dec 31, 2021 1.47 Mn