Pyxis Oncology (PYXS) Return on Equity (2021 - 2025)

Pyxis Oncology (PYXS) reported Return on Equity of 0.01% for Q4 2025, down 1.0% year-over-year from 0.01% in Q4 2024, and down 5.06% quarter-over-quarter from 0.01% in Q3 2025.

Pyxis Oncology (PYXS) Return on Equity (2021 - 2025) Analysis & Trends

Pyxis Oncology (PYXS) has 5 years of Return on Equity data on file, last reported at 0.01% in Q4 2025.

  • Return on Equity for Q4 2025 came in at 0.01%, down 1.0% year-over-year; the trailing twelve-month figure through Dec 2025 was 0.01% (down 1.0% YoY), and the FY2025 annual result was 0.01%, changed 0.0% from the prior year.
  • Return on Equity eased to 0.01% in Q4 2025 per PYXS's latest filing, from 0.01% in the prior quarter.
  • Over five years, Return on Equity peaked at 0.01% in Q2 2021 and troughed at 0.01% in Q4 2025.
  • A 5-year average of 0.01% and a median of 0.01% in 2024 frame the typical range for Return on Equity.
  • On a YoY basis, Return on Equity climbed as much as 0 bps in 2022 and fell as far as 1 bps in 2022.
  • A 5-year view of Return on Equity shows it stood at 0.01% in 2021, then increased by 6 bps to 0.01% in 2022, then grew by 16 bps to 0.01% in 2023, then declined by 0 bps to 0.01% in 2024, then slumped by 126 bps to 0.01% in 2025.
  • Business Quant data shows PYXS's Return on Equity at 0.01% in Q4 2025, 0.01% in Q3 2025, and 0.01% in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROE (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -0.81%
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -0.04%
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 0.00%
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -0.01%
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 0.00%
9 Abivax 91.96 Bn 91.96 Bn - -0.01%
10 Pyxis Oncology 125.84 Mn 108.95 Mn 8.65 Mn -0.01%

Historic Data

Download Data
DateValue
Dec 31, 2025 -0.01%
Sep 30, 2025 -0.01%
Jun 30, 2025 -0.01%
Mar 31, 2025 -0.01%
Dec 31, 2024 -0.01%
Sep 30, 2024 0.00%
Jun 30, 2024 0.00%
Mar 31, 2024 0.00%
Dec 31, 2023 -0.01%
Sep 30, 2023 -0.01%
Jun 30, 2023 -0.01%
Mar 31, 2023 -0.01%
Dec 31, 2022 -0.01%
Sep 30, 2022 -0.01%
Jun 30, 2022 0.00%
Mar 31, 2022 0.00%
Dec 31, 2021 -0.01%
Sep 30, 2021 0.01%
Jun 30, 2021 0.01%