Pyxis Oncology (PYXS) Equity Average (2020 - 2025)
Pyxis Oncology (PYXS) reported Equity Average of $61.1 million for Q4 2025, down 55.48% year-over-year from $137.2 million in Q4 2024, and down 21.89% quarter-over-quarter from $78.2 million in Q3 2025.
Pyxis Oncology (PYXS) Equity Average (2020 - 2025) Analysis & Trends
Pyxis Oncology (PYXS) has 6 years of Equity Average data on file, last reported at $61.1 million in Q4 2025.
- Equity Average for Q4 2025 came in at $61.1 million, down 55.48% year-over-year; the trailing twelve-month figure through Dec 2025 was $61.1 million (down 55.48% YoY), and the FY2025 annual result was $87.1 million, down 29.33% from the prior year.
- Equity Average fell to $61.1 million in Q4 2025 per PYXS's latest filing, from $78.2 million in the prior quarter.
- Over five years, Equity Average peaked at $247.4 million in Q1 2022 and troughed at -$64.5 million in Q3 2021.
- A 5-year average of $117.3 million and a median of $139.4 million in 2023 frame the typical range for Equity Average.
- The sharpest annual moves came in 2022 and 2025: Equity Average jumped 853.6% in 2022, then plunged 55.48% in 2025.
- A 5-year view of Equity Average shows it stood at $94.9 million in 2021, then soared by 84.11% to $174.8 million in 2022, then fell by 24.58% to $131.8 million in 2023, then gained by 4.09% to $137.2 million in 2024, then tumbled by 55.48% to $61.1 million in 2025.
- Business Quant data shows PYXS's Equity Average at $61.1 million in Q4 2025, $78.2 million in Q3 2025, and $95.4 million in Q2 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Equity Avg. (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | 3.50 Bn |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | 783.14 Mn |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | 3.76 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | 1.01 Bn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | 21.35 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 19.01 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | 516.41 Mn |
| 10 | Pyxis Oncology | 125.84 Mn | 108.95 Mn | 8.65 Mn | 61.09 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | 61.09 Mn |
| Sep 30, 2025 | 78.21 Mn |
| Jun 30, 2025 | 95.37 Mn |
| Mar 31, 2025 | 111.93 Mn |
| Dec 31, 2024 | 137.22 Mn |
| Sep 30, 2024 | 161.74 Mn |
| Jun 30, 2024 | 176.98 Mn |
| Mar 31, 2024 | 154.93 Mn |
| Dec 31, 2023 | 131.83 Mn |
| Sep 30, 2023 | 141.61 Mn |
| Jun 30, 2023 | 148.72 Mn |
| Mar 31, 2023 | 156.49 Mn |
| Dec 31, 2022 | 174.79 Mn |
| Sep 30, 2022 | 200.36 Mn |
| Jun 30, 2022 | 222.74 Mn |
| Mar 31, 2022 | 247.41 Mn |
| Dec 31, 2021 | 94.94 Mn |
| Sep 30, 2021 | -64.51 Mn |
| Jun 30, 2021 | -53.80 Mn |
| Mar 31, 2021 | -32.83 Mn |