Pyxis Oncology PYXS
NASDAQ PYXS
$3.08 -0.04 (-1.28%)
At close: Aug 21, 2026 · 4:00 PM EDT

Pyxis Oncology (PYXS) Cash & Current Investments (2020 - 2026)

Pyxis Oncology (PYXS) posted quarterly Cash & Current Investments of $66.9 million for Q4 2025, down 47.33% year-over-year from $126.9 million in Q4 2024, and down 12.33% quarter-over-quarter from $76.3 million in Q3 2025.

Pyxis Oncology (PYXS) Cash & Current Investments (2020 - 2026) Analysis & Trends

Pyxis Oncology (PYXS) has reported Cash & Current Investments for 6 consecutive years, with $66.9 million the latest figure, recorded in Q4 2025.

  • In Q4 2025, Cash & Current Investments fell 47.33% year-over-year to $66.9 million; the TTM figure through Dec 2025 stood at $66.9 million (down 47.33% YoY), while the FY2025 annual figure was $66.9 million, down 47.33% from the prior year.
  • Cash & Current Investments fell to $66.9 million in Q4 2025 per PYXS's latest filing, from $76.3 million in the prior quarter.
  • Across five years, Cash & Current Investments topped out at $276.2 million in Q4 2021 and bottomed at $12.2 million in Q2 2025.
  • Historically, Cash & Current Investments has averaged $118.9 million across 5 years, with a median of $129.9 million in 2023.
  • Annual changes were most pronounced in 2021 — Cash & Current Investments soared 1086.88% — and 2023, when it sank 87.83%.
  • Pyxis Oncology's Cash & Current Investments stood at $276.2 million in 2021, then tumbled by 34.55% to $180.8 million in 2022, then slumped by 34.0% to $119.3 million in 2023, then rose by 6.4% to $126.9 million in 2024, then tumbled by 47.33% to $66.9 million in 2025.
  • Business Quant data shows PYXS's Cash & Current Investments at $66.9 million in Q4 2025, $76.3 million in Q3 2025, and $12.2 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Cash & Current Investments (Qtr)
1 Vertex Pharmaceuticals 139.13 Bn 131.28 Bn 2.84 Bn 7.85 Bn
2 Regeneron Pharmaceuticals 85.77 Bn 77.77 Bn 3.93 Bn 7.99 Bn
3 Argenx Se 64.64 Bn 59.46 Bn 1.37 Bn 5.18 Bn
4 Moderna 58.29 Bn 53.16 Bn 52.00 Mn 5.14 Bn
5 BeOne Medicines 41.92 Bn 36.82 Bn 1.53 Bn 5.10 Bn
6 Alnylam Pharmaceuticals 31.58 Bn 28.28 Bn 992.69 Mn 3.31 Bn
7 BioNTech SE 28.12 Bn 9.73 Bn 668.28 Mn 18.39 Bn
8 Insmed 27.39 Bn 26.22 Bn 358.27 Mn 1.16 Bn
9 Royalty Pharma 27.27 Bn 26.43 Bn - 836.99 Mn
10 Pyxis Oncology 198.37 Mn 165.38 Mn - 33.00 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 33.00 Mn
Dec 31, 2025 66.86 Mn
Sep 30, 2025 76.26 Mn
Jun 30, 2025 12.21 Mn
Mar 31, 2025 14.23 Mn
Dec 31, 2024 126.93 Mn
Sep 30, 2024 144.82 Mn
Jun 30, 2024 26.55 Mn
Mar 31, 2024 29.44 Mn
Dec 31, 2023 119.30 Mn
Sep 30, 2023 132.97 Mn
Jun 30, 2023 27.37 Mn
Mar 31, 2023 54.53 Mn
Dec 31, 2022 180.77 Mn
Sep 30, 2022 200.01 Mn
Jun 30, 2022 224.83 Mn
Mar 31, 2022 248.56 Mn
Dec 31, 2021 276.21 Mn
Sep 30, 2021 133.48 Mn
Jun 30, 2021 142.47 Mn