Growth Metrics

Palvella Therapeutics (PVLA) Operating Income (2013 - 2026)

Palvella Therapeutics (PVLA) reported Operating Income of -$14.9 million for Q1 2026, down 88.73% year-over-year from -$131.8 million in Q1 2025, and down 180.13% on a QoQ basis from $18.5 million in Q4 2025.

Palvella Therapeutics (PVLA) has 14 years of Operating Income data on file, last reported at -$14.9 million in Q1 2026.

  • Quarterly Operating Income fell 88.73% year-over-year to -$14.9 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$15.7 million (up 22.09% YoY) and the FY2025 annual result came in at -$8.8 million, up 37.85% from the prior year.
  • Operating Income fell to -$14.9 million in Q1 2026 per PVLA's latest filing, from $18.5 million in the prior quarter.
  • Across five years, Operating Income topped out at $18.5 million in Q4 2025 and bottomed at -$15.5 million in Q1 2023.
  • The 5-year median for Operating Income is -$7.7 million (2022), against an average of -$5.1 million.
  • Peak annual rise in Operating Income reached 524.6% in 2025, while the deepest fall reached 347.47% in 2025.
  • Tracing PVLA's Operating Income over 5 years: stood at -$12.2 million in 2022, then jumped by 210.01% to $13.4 million in 2023, then plunged by 132.62% to -$4.4 million in 2024, then jumped by 524.6% to $18.5 million in 2025, then sank by 180.13% to -$14.9 million in 2026.
  • Per Business Quant, the three latest PVLA Operating Income figures stand at -$14.9 million (Q1 2026), $18.5 million (Q4 2025), and -$10.2 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -2.97 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -19.70 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -15.76 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 1.14 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -3.82 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 642.90 Mn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 268.64 Mn
10 Palvella Therapeutics 1.47 Bn 1.21 Bn - -14.86 Mn

Historic Data

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DateValue
Mar 31, 2026 -14.86 Mn
Dec 31, 2025 18.54 Mn
Sep 30, 2025 -10.18 Mn
Jun 30, 2025 -9.25 Mn
Mar 31, 2025 -7.87 Mn
Dec 31, 2024 -4.37 Mn
Sep 30, 2024 -5.06 Mn
Jun 30, 2024 -2.91 Mn
Mar 31, 2024 -1.76 Mn
Dec 31, 2023 13.39 Mn
Sep 30, 2023 -11.81 Mn
Jun 30, 2023 2.06 Mn
Mar 31, 2023 -15.51 Mn
Sep 30, 2022 -12.17 Mn
Jun 30, 2022 -12.33 Mn
Mar 31, 2022 -7.46 Mn
Dec 31, 2021 -11.00 Mn
Sep 30, 2021 -19.01 Mn
Jun 30, 2021 -16.76 Mn
Mar 31, 2021 -5.06 Mn
Dec 31, 2020 -12.41 Mn
Sep 30, 2020 -13.00 Mn
Jun 30, 2020 -4.66 Mn
Mar 31, 2020 -3.86 Mn
Dec 31, 2019 -1.33 Mn
Sep 30, 2019 -2.91 Mn
Jun 30, 2019 -12.23 Mn
Mar 31, 2019 -10.68 Mn
Dec 31, 2018 -12.65 Mn
Sep 30, 2018 -7.80 Mn
Jun 30, 2018 -2.24 Mn
Mar 31, 2018 -8.14 Mn
Dec 31, 2017 6.49 Mn
Sep 30, 2017 -5.18 Mn
Jun 30, 2017 -7.89 Mn
Mar 31, 2017 -8.01 Mn
Dec 31, 2016 -6.40 Mn
Sep 30, 2016 -6.18 Mn
Jun 30, 2016 -5.80 Mn
Mar 31, 2016 -4.38 Mn
Dec 31, 2015 -2.57 Mn
Sep 30, 2015 -3.88 Mn
Jun 30, 2015 -3.53 Mn
Mar 31, 2015 -3.70 Mn
Sep 30, 2014 -1.84 Mn
Jun 30, 2014 -2.77 Mn
Mar 31, 2014 -671,217.00
Dec 31, 2013 -2,198.00
Sep 30, 2013 -5,762.00
Jun 30, 2013 -274.00