Protagonist Therapeutics PTGX
NASDAQ PTGX
$134.86 -1.40 (-1.03%)
At close: Nov 11, 2026 · 4:00 PM EST

Protagonist Therapeutics (PTGX) Return on Equity [ROE] (2016 - 2026)

Updated

Protagonist Therapeutics (PTGX) reported Return on Equity [ROE] of 11.08% for Q2 2026, up 3.41 percentage points from 7.67% a year earlier and up 29.14 percentage points from the prior quarter.

Analysis

Protagonist Therapeutics (PTGX) Return on Equity [ROE] (2016 - 2026) Analysis & Trends

For FY2025, Protagonist Therapeutics posted Return on Equity [ROE] of -20.18%, down 74.56 percentage points from FY2024.

  • Return on Equity [ROE] has a five-year change of +16.62 percentage points (FY2020 to FY2025).
  • By year, Return on Equity [ROE] came in at 54.39% in FY2024 (+82.98 pp), -28.59% in FY2023 (+20.82 pp), -49.41% in FY2022 (-6.09 pp) and -43.32% in FY2021 (-6.53 pp).
  • The Q2 2026 figure ranks as the highest quarterly Return on Equity [ROE] since Q4 2024.
  • Year over year, Return on Equity [ROE] gained in three of the last eight quarters, with an average year-over-year change of -1.97 percentage points.
  • The high point for year-over-year Return on Equity [ROE] in five years was Q1 2024 (a gain of 101.03 percentage points); the low point was Q4 2025 (a drop of 66.25 percentage points).
  • Per Business Quant data, the three quarters before Q2 2026 came in at -18.06% (Q1 2026), -20.66% (Q4 2025) and 6.99% (Q3 2025).
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROE (Qtr)
1 Eli Lilly 1,348.13 Bn 1,321.74 Bn 20.46 Bn 74.39%
2 Johnson & Johnson 675.90 Bn 595.76 Bn 17.30 Bn 19.33%
3 AbbVie 519.45 Bn 487.50 Bn 13.12 Bn -
4 Merck 364.95 Bn 327.95 Bn 13.19 Bn 5.63%
5 Novartis Ag 311.58 Bn 285.16 Bn - -
6 Astrazeneca 289.34 Bn 262.94 Bn 13.26 Bn 21.60%
7 Amgen 251.64 Bn 203.30 Bn 7.58 Bn 72.13%
8 Gilead Sciences 212.05 Bn 187.07 Bn 6.73 Bn -31.17%
9 Pfizer 167.35 Bn 115.00 Bn 12.56 Bn 4.66%
10 Protagonist Therapeutics 8.89 Bn 6.19 Bn 273.31 Mn 35.53%
Historic Data

Historic Data

Download Data
DateValue
Sep 30, 2026 35.53%
Jun 30, 2026 11.08%
Mar 31, 2026 -18.06%
Dec 31, 2025 -20.66%
Sep 30, 2025 6.99%
Jun 30, 2025 7.67%
Mar 31, 2025 8.24%
Dec 31, 2024 45.59%
Sep 30, 2024 31.84%
Jun 30, 2024 30.86%
Mar 31, 2024 36.14%
Dec 31, 2023 -24.72%
Sep 30, 2023 -47.15%
Jun 30, 2023 -53.93%
Mar 31, 2023 -64.89%
Dec 31, 2022 -55.45%
Sep 30, 2022 -50.80%
Jun 30, 2022 -46.55%
Mar 31, 2022 -40.71%
Dec 31, 2021 -39.88%
API Access

Protagonist Therapeutics Return on Equity [ROE] API

Pull this series into your own models, spreadsheets and apps with the Business Quant Historical Metrics API. The request below matches the chart above — change the frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.

https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=PTGX&period=max&api_key=YOUR_API_KEY