Protagonist Therapeutics (PTGX) Return on Equity [ROE] (2016 - 2026)
Protagonist Therapeutics (PTGX) reported Return on Equity [ROE] of 11.08% for Q2 2026, up 3.41 percentage points from 7.67% a year earlier and up 29.14 percentage points from the prior quarter.
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Analysis
Protagonist Therapeutics (PTGX) Return on Equity [ROE] (2016 - 2026) Analysis & Trends
For FY2025, Protagonist Therapeutics posted Return on Equity [ROE] of -20.18%, down 74.56 percentage points from FY2024.
- Return on Equity [ROE] has a five-year change of +16.62 percentage points (FY2020 to FY2025).
- By year, Return on Equity [ROE] came in at 54.39% in FY2024 (+82.98 pp), -28.59% in FY2023 (+20.82 pp), -49.41% in FY2022 (-6.09 pp) and -43.32% in FY2021 (-6.53 pp).
- The Q2 2026 figure ranks as the highest quarterly Return on Equity [ROE] since Q4 2024.
- Year over year, Return on Equity [ROE] gained in three of the last eight quarters, with an average year-over-year change of -1.97 percentage points.
- The high point for year-over-year Return on Equity [ROE] in five years was Q1 2024 (a gain of 101.03 percentage points); the low point was Q4 2025 (a drop of 66.25 percentage points).
- Per Business Quant data, the three quarters before Q2 2026 came in at -18.06% (Q1 2026), -20.66% (Q4 2025) and 6.99% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROE (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 638.12 Bn | 556.64 Bn | 17.26 Bn | 25.32% |
| 2 | AbbVie | 462.60 Bn | 435.75 Bn | 12.70 Bn | - |
| 3 | Merck | 358.70 Bn | 313.13 Bn | 12.21 Bn | 7.21% |
| 4 | Novartis Ag | 272.16 Bn | 228.03 Bn | 11.24 Bn | 84.40% |
| 5 | Astrazeneca | 250.36 Bn | 223.92 Bn | 12.86 Bn | 21.39% |
| 6 | Amgen | 227.87 Bn | 183.27 Bn | 7.24 Bn | 83.75% |
| 7 | Gilead Sciences | 184.97 Bn | 159.08 Bn | 6.22 Bn | -18.38% |
| 8 | Pfizer | 162.61 Bn | 109.56 Bn | 10.94 Bn | 4.97% |
| 9 | Vertex Pharmaceuticals | 132.45 Bn | 104.46 Bn | 2.84 Bn | 22.24% |
| 10 | Protagonist Therapeutics | 9.11 Bn | 9.11 Bn | - | 11.08% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 11.08% |
| Mar 31, 2026 | -18.06% |
| Dec 31, 2025 | -20.66% |
| Sep 30, 2025 | 6.99% |
| Jun 30, 2025 | 7.67% |
| Mar 31, 2025 | 8.24% |
| Dec 31, 2024 | 45.59% |
| Sep 30, 2024 | 31.84% |
| Jun 30, 2024 | 30.86% |
| Mar 31, 2024 | 36.14% |
| Dec 31, 2023 | -24.72% |
| Sep 30, 2023 | -47.15% |
| Jun 30, 2023 | -53.93% |
| Mar 31, 2023 | -64.89% |
| Dec 31, 2022 | -55.45% |
| Sep 30, 2022 | -50.80% |
| Jun 30, 2022 | -46.55% |
| Mar 31, 2022 | -40.71% |
| Dec 31, 2021 | -39.88% |
| Sep 30, 2021 | -31.30% |
API Access
Protagonist Therapeutics Return on Equity [ROE] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=PTGX&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-equity-[roe]", "ticker": "PTGX", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=PTGX&period=max&api_key=YOUR_API_KEY");
const data = await res.json();