Protagonist Therapeutics (PTGX) Net Margin (2017 - 2026)
Protagonist Therapeutics' (PTGX) quarterly Net Margin came in at 6.71% in Q1 2026, up 4786.0% year-on-year from 0.14% in Q1 2025, and up 101.12% quarter-over-quarter from 596.8% in Q4 2025.
Protagonist Therapeutics (PTGX) Net Margin (2017 - 2026) Analysis & Trends
Protagonist Therapeutics has disclosed Net Margin across 10 years of filings, most recently posting 6.71% for Q1 2026.
- Net Margin for Q1 2026 came in at 6.71%, up 4786.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 154.92% (down 4453.0% YoY), and the FY2025 annual result was 282.83%, down 28187.0% from the prior year.
- Net Margin came in at 6.71% for Q1 2026 at Protagonist Therapeutics, up from 596.8% in the prior quarter.
- In the past five years, Net Margin ranged from a high of 180342.11% in Q4 2022 to a low of 4768.22% in Q2 2022.
- The 5-year median for Net Margin is 89.52% (2024), against an average of 13247.62%.
- Across the five-year window, Net Margin surged 18077041 bps in 2022 and plunged 18006876 bps in 2023, its largest moves.
- Protagonist Therapeutics' Net Margin stood at 180342.11% in 2022, then sank by 100 bps to 273.35% in 2023, then sank by 133 bps to 89.52% in 2024, then slumped by 567 bps to 596.8% in 2025, then surged by 101 bps to 6.71% in 2026.
- The last three Net Margin figures came in at 6.71% (Q1 2026), 596.8% (Q4 2025), and 834.87% (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | - |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | 0.82% |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | - |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 34.53% |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | - |
| 10 | Protagonist Therapeutics | 7.35 Bn | 7.35 Bn | - | 6.71% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 6.71% |
| Dec 31, 2025 | -596.80% |
| Sep 30, 2025 | -834.87% |
| Jun 30, 2025 | -627.46% |
| Mar 31, 2025 | -41.15% |
| Dec 31, 2024 | -89.52% |
| Sep 30, 2024 | -710.80% |
| Jun 30, 2024 | -734.15% |
| Mar 31, 2024 | 81.33% |
| Dec 31, 2023 | 273.35% |
| Dec 31, 2022 | 180,342.11% |
| Jun 30, 2022 | -4,768.22% |
| Mar 31, 2022 | -81.42% |
| Dec 31, 2021 | -428.30% |
| Sep 30, 2021 | -328.64% |
| Jun 30, 2021 | -1,361.68% |
| Mar 31, 2021 | -387.75% |
| Dec 31, 2020 | -419.93% |
| Sep 30, 2020 | -59.20% |
| Mar 31, 2019 | -904.04% |