Protagonist Therapeutics PTGX
NASDAQ PTGX
$140.97 -1.47 (-1.03%)
At close: Sep 29, 2026 · 4:00 PM EDT

Protagonist Therapeutics (PTGX) Net Margin (2017 - 2026)

Updated

Protagonist Therapeutics (PTGX) reported Net Margin of 76.28% for Q2 2026, up 703.24 percentage points from -626.96% a year earlier and up 69.57 percentage points from the prior quarter.

Analysis

Protagonist Therapeutics (PTGX) Net Margin (2017 - 2026) Analysis & Trends

Over the twelve months ended Jun 30, 2026, Protagonist Therapeutics' Net Margin came in at 29.40%, up 4.52 percentage points year-over-year; for FY2025, it was -282.83%, down 346.18 percentage points from FY2024.

  • Net Margin has a five-year change of -51.77 percentage points (FY2020 to FY2025).
  • By year, Net Margin came in at 63.34% in FY2024 (+194.94 pp), -131.59% in FY2023 (+347.67 pp), -479.26% in FY2022 (-20.33 pp) and -458.94% in FY2021 (-227.87 pp).
  • The Q2 2026 figure ranks as the highest quarterly Net Margin since Q4 2024.
  • Year over year, Net Margin gained in four of the last seven quarters, with an average year-over-year change of -4.35 percentage points.
  • The high point for year-over-year Net Margin in five years was Q2 2026 (a gain of 703.24 percentage points); the low point was Q2 2022 (a drop of 3197.99 percentage points).
  • Per Business Quant data, the three quarters before Q2 2026 came in at 6.71% (Q1 2026), -596.80% (Q4 2025) and -834.87% (Q3 2025).
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Margin (Qtr)
1 Johnson & Johnson 655.56 Bn 574.09 Bn 17.26 Bn 21.86%
2 AbbVie 470.94 Bn 444.10 Bn 12.70 Bn 21.27%
3 Merck 367.14 Bn 321.57 Bn 12.21 Bn -8.04%
4 Novartis Ag 280.33 Bn 236.20 Bn 11.24 Bn 22.61%
5 Astrazeneca 257.78 Bn 231.34 Bn 12.86 Bn 18.81%
6 Amgen 226.04 Bn 181.44 Bn 7.24 Bn 23.62%
7 Gilead Sciences 188.89 Bn 163.01 Bn 6.22 Bn -134.51%
8 Pfizer 163.75 Bn 110.70 Bn 10.94 Bn -1.65%
9 Vertex Pharmaceuticals 133.68 Bn 105.69 Bn 2.84 Bn 32.99%
10 Protagonist Therapeutics 9.21 Bn 9.21 Bn - 76.28%
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 76.28%
Mar 31, 2026 6.71%
Dec 31, 2025 -596.80%
Sep 30, 2025 -834.87%
Jun 30, 2025 -626.96%
Mar 31, 2025 -41.15%
Dec 31, 2024 77.17%
Sep 30, 2024 -710.37%
Jun 30, 2024 -734.73%
Mar 31, 2024 81.32%
Dec 31, 2023 45.56%
Jun 30, 2022 -4,559.67%
Mar 31, 2022 -81.37%
Dec 31, 2021 -428.30%
Sep 30, 2021 -328.64%
Jun 30, 2021 -1,361.68%
Mar 31, 2021 -387.75%
Dec 31, 2020 -334.27%
Sep 30, 2020 -59.20%
Jun 30, 2020 -312.39%
API Access

Protagonist Therapeutics Net Margin API

Pull this series into your own models, spreadsheets and apps with the Business Quant Historical Metrics API. The request below matches the chart above — change the frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.

https://data.businessquant.com/historic?slug=net-margin&ticker=PTGX&period=max&api_key=YOUR_API_KEY