Protagonist Therapeutics (PTGX) Net Margin (2017 - 2026)

Protagonist Therapeutics' (PTGX) quarterly Net Margin came in at 6.71% in Q1 2026, up 4786.0% year-on-year from 0.14% in Q1 2025, and up 101.12% quarter-over-quarter from 596.8% in Q4 2025.

Protagonist Therapeutics (PTGX) Net Margin (2017 - 2026) Analysis & Trends

Protagonist Therapeutics has disclosed Net Margin across 10 years of filings, most recently posting 6.71% for Q1 2026.

  • Net Margin for Q1 2026 came in at 6.71%, up 4786.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 154.92% (down 4453.0% YoY), and the FY2025 annual result was 282.83%, down 28187.0% from the prior year.
  • Net Margin came in at 6.71% for Q1 2026 at Protagonist Therapeutics, up from 596.8% in the prior quarter.
  • In the past five years, Net Margin ranged from a high of 180342.11% in Q4 2022 to a low of 4768.22% in Q2 2022.
  • The 5-year median for Net Margin is 89.52% (2024), against an average of 13247.62%.
  • Across the five-year window, Net Margin surged 18077041 bps in 2022 and plunged 18006876 bps in 2023, its largest moves.
  • Protagonist Therapeutics' Net Margin stood at 180342.11% in 2022, then sank by 100 bps to 273.35% in 2023, then sank by 133 bps to 89.52% in 2024, then slumped by 567 bps to 596.8% in 2025, then surged by 101 bps to 6.71% in 2026.
  • The last three Net Margin figures came in at 6.71% (Q1 2026), 596.8% (Q4 2025), and 834.87% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Margin (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 0.82%
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 34.53%
9 Abivax 91.96 Bn 91.96 Bn - -
10 Protagonist Therapeutics 7.35 Bn 7.35 Bn - 6.71%

Historic Data

Download Data
DateValue
Mar 31, 2026 6.71%
Dec 31, 2025 -596.80%
Sep 30, 2025 -834.87%
Jun 30, 2025 -627.46%
Mar 31, 2025 -41.15%
Dec 31, 2024 -89.52%
Sep 30, 2024 -710.80%
Jun 30, 2024 -734.15%
Mar 31, 2024 81.33%
Dec 31, 2023 273.35%
Dec 31, 2022 180,342.11%
Jun 30, 2022 -4,768.22%
Mar 31, 2022 -81.42%
Dec 31, 2021 -428.30%
Sep 30, 2021 -328.64%
Jun 30, 2021 -1,361.68%
Mar 31, 2021 -387.75%
Dec 31, 2020 -419.93%
Sep 30, 2020 -59.20%
Mar 31, 2019 -904.04%