Protagonist Therapeutics (PTGX) Net Margin (2017 - 2026)
Protagonist Therapeutics (PTGX) reported Net Margin of 76.28% for Q2 2026, up 703.24 percentage points from -626.96% a year earlier and up 69.57 percentage points from the prior quarter.
Protagonist Therapeutics (PTGX) Net Margin (2017 - 2026) Analysis & Trends
Over the twelve months ended Jun 30, 2026, Protagonist Therapeutics' Net Margin came in at 29.40%, up 4.52 percentage points year-over-year; for FY2025, it was -282.83%, down 346.18 percentage points from FY2024.
- Net Margin has a five-year change of -51.77 percentage points (FY2020 to FY2025).
- By year, Net Margin came in at 63.34% in FY2024 (+194.94 pp), -131.59% in FY2023 (+347.67 pp), -479.26% in FY2022 (-20.33 pp) and -458.94% in FY2021 (-227.87 pp).
- The Q2 2026 figure ranks as the highest quarterly Net Margin since Q4 2024.
- Year over year, Net Margin gained in four of the last seven quarters, with an average year-over-year change of -4.35 percentage points.
- The high point for year-over-year Net Margin in five years was Q2 2026 (a gain of 703.24 percentage points); the low point was Q2 2022 (a drop of 3197.99 percentage points).
- Per Business Quant data, the three quarters before Q2 2026 came in at 6.71% (Q1 2026), -596.80% (Q4 2025) and -834.87% (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 21.86% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 21.27% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | -8.04% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | 22.61% |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 18.81% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 23.62% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -134.51% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | -1.65% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 32.99% |
| 10 | Protagonist Therapeutics | 9.21 Bn | 9.21 Bn | - | 76.28% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 76.28% |
| Mar 31, 2026 | 6.71% |
| Dec 31, 2025 | -596.80% |
| Sep 30, 2025 | -834.87% |
| Jun 30, 2025 | -626.96% |
| Mar 31, 2025 | -41.15% |
| Dec 31, 2024 | 77.17% |
| Sep 30, 2024 | -710.37% |
| Jun 30, 2024 | -734.73% |
| Mar 31, 2024 | 81.32% |
| Dec 31, 2023 | 45.56% |
| Jun 30, 2022 | -4,559.67% |
| Mar 31, 2022 | -81.37% |
| Dec 31, 2021 | -428.30% |
| Sep 30, 2021 | -328.64% |
| Jun 30, 2021 | -1,361.68% |
| Mar 31, 2021 | -387.75% |
| Dec 31, 2020 | -334.27% |
| Sep 30, 2020 | -59.20% |
| Jun 30, 2020 | -312.39% |
Protagonist Therapeutics Net Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=net-margin&ticker=PTGX&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "net-margin", "ticker": "PTGX", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=net-margin&ticker=PTGX&period=max&api_key=YOUR_API_KEY");
const data = await res.json();