Protagonist Therapeutics (PTGX) Net Cash Flow (2015 - 2026)

Protagonist Therapeutics' (PTGX) quarterly Net Cash Flow came in at $65.3 million in Q1 2026, up 54.05% year-on-year from $42.4 million in Q1 2025, and up 345.07% quarter-over-quarter from $14.7 million in Q4 2025.

Protagonist Therapeutics (PTGX) Net Cash Flow (2015 - 2026) Analysis & Trends

Protagonist Therapeutics has disclosed Net Cash Flow across 12 years of filings, most recently posting $65.3 million for Q1 2026.

  • Net Cash Flow for Q1 2026 came in at $65.3 million, up 54.05% year-over-year; the trailing twelve-month figure through Mar 2026 was $54.1 million (up 264.43% YoY), and the FY2025 annual result was $31.2 million, up 134.87% from the prior year.
  • Net Cash Flow came in at $65.3 million for Q1 2026 at Protagonist Therapeutics, up from $14.7 million in the prior quarter.
  • In the past five years, Net Cash Flow ranged from a high of $183.1 million in Q2 2024 to a low of -$224.5 million in Q3 2024.
  • The 5-year median for Net Cash Flow is $1.9 million (2023), against an average of $4.1 million.
  • Across the five-year window, Net Cash Flow plunged 4524.55% in 2024 and jumped 399.48% in 2025, its largest moves.
  • Protagonist Therapeutics' Net Cash Flow stood at -$27.1 million in 2022, then slumped by 61.34% to -$43.8 million in 2023, then rose by 22.67% to -$33.9 million in 2024, then jumped by 143.33% to $14.7 million in 2025, then soared by 345.07% to $65.3 million in 2026.
  • The last three Net Cash Flow figures came in at $65.3 million (Q1 2026), $14.7 million (Q4 2025), and -$54.8 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Cash Flow (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - 2.44 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 625.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -2.44 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 457.40 Mn
9 Abivax 91.96 Bn 91.96 Bn - 664,983.53
10 Protagonist Therapeutics 7.35 Bn 7.35 Bn - 65.32 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 65.32 Mn
Mar 31, 2026 65.32 Mn
Dec 31, 2025 14.68 Mn
Dec 31, 2025 14.68 Mn
Sep 30, 2025 -54.83 Mn
Sep 30, 2025 -54.83 Mn
Jun 30, 2025 28.96 Mn
Jun 30, 2025 28.96 Mn
Mar 31, 2025 42.40 Mn
Mar 31, 2025 42.40 Mn
Dec 31, 2024 -33.87 Mn
Dec 31, 2024 -33.87 Mn
Sep 30, 2024 -224.52 Mn
Sep 30, 2024 -224.52 Mn
Jun 30, 2024 183.08 Mn
Jun 30, 2024 183.08 Mn
Mar 31, 2024 -14.16 Mn
Mar 31, 2024 -14.16 Mn
Dec 31, 2023 -43.80 Mn
Dec 31, 2023 -43.80 Mn