Protagonist Therapeutics (PTGX) Net Cash Flow (2015 - 2026)

Protagonist Therapeutics (PTGX) posted Net Cash Flow of $65.3 million for Q1 2026, up 345.07% sequentially from $14.7 million in Q4 2025, and up 54.05% YoY from $42.4 million in Q1 2025.

Protagonist Therapeutics (PTGX) Net Cash Flow (2015 - 2026) Analysis & Trends

Protagonist Therapeutics has reported Net Cash Flow for 12 years, with the latest figure at $65.3 million in Q1 2026.

  • Quarterly Net Cash Flow rose 54.05% year-over-year to $65.3 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $54.1 million (up 264.43% YoY) and the FY2025 annual result came in at $31.2 million, up 134.87% from the prior year.
  • Net Cash Flow improved to $65.3 million in Q1 2026 per PTGX's latest filing, from $14.7 million in the prior quarter.
  • Over five years, Net Cash Flow peaked at $183.1 million in Q2 2024 and troughed at -$224.5 million in Q3 2024.
  • A 5-year average of $4.1 million and a median of $1.9 million in 2023 frame the typical range for Net Cash Flow.
  • The sharpest annual moves came in 2024 and 2025: Net Cash Flow plunged 4524.55% in 2024, then soared 399.48% in 2025.
  • Over 5 years, Net Cash Flow stood at -$27.1 million in 2022, then slumped by 61.34% to -$43.8 million in 2023, then advanced by 22.67% to -$33.9 million in 2024, then soared by 143.33% to $14.7 million in 2025, then surged by 345.07% to $65.3 million in 2026.
  • According to Business Quant data, Net Cash Flow over the past three periods registered $65.3 million, $14.7 million, and -$54.8 million for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Cash Flow (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 652.90 Mn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn -504.30 Mn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn -
4 Revolution Medicines 43.64 Bn 43.64 Bn - 374.50 Mn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 407.41 Mn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn 17.81 Mn
7 Royalty Pharma 33.72 Bn 35.84 Bn - 225.59 Mn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn -496,000.00
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -37.14 Mn
10 Protagonist Therapeutics 10.03 Bn 10.03 Bn - 226.37 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 226.37 Mn
Jun 30, 2026 226.37 Mn
Mar 31, 2026 65.32 Mn
Mar 31, 2026 65.32 Mn
Dec 31, 2025 14.68 Mn
Dec 31, 2025 14.68 Mn
Sep 30, 2025 -54.83 Mn
Sep 30, 2025 -54.83 Mn
Jun 30, 2025 28.96 Mn
Jun 30, 2025 28.96 Mn
Mar 31, 2025 42.40 Mn
Mar 31, 2025 42.40 Mn
Dec 31, 2024 -33.87 Mn
Dec 31, 2024 -33.87 Mn
Sep 30, 2024 -224.52 Mn
Sep 30, 2024 -224.52 Mn
Jun 30, 2024 183.08 Mn
Jun 30, 2024 183.08 Mn
Mar 31, 2024 -14.16 Mn
Mar 31, 2024 -14.16 Mn