Protagonist Therapeutics (PTGX) Interest Expenses (2015 - 2025)

Protagonist Therapeutics (PTGX) reported Interest Expenses of $501.3 million for Q4 2025, up 59507.61% on a YoY basis from N/an in Q4 2024, and up 59507.61% sequentially from $841000.0 in Q4 2024.

Protagonist Therapeutics (PTGX) Interest Expenses (2015 - 2025) Analysis & Trends

Protagonist Therapeutics (PTGX) has 11 years of Interest Expenses data on file, last reported at $501.3 million in Q4 2025.

  • For the quarter ending Q4 2025, Interest Expenses rose 59507.61% year-over-year to $501.3 million; the trailing twelve-month figure through Dec 2025 stood at $501.3 million (up 85886.28% YoY), and the FY2025 full-year result was $501.3 million, up 227.86% from the prior year.
  • Interest Expenses climbed to $501.3 million in Q4 2025, from $841000.0 in the prior quarter.
  • In the past five years, Interest Expenses ranged from a high of $501.3 million in Q4 2025 to a low of -$1.6 million in Q4 2023.
  • A 5-year average of $57.6 million and a median of $2.1 million in 2024 frame the typical range for Interest Expenses.
  • Across the five-year window, Interest Expenses slumped 344.0% in 2023 and soared 59507.61% in 2025, its largest moves.
  • Tracing PTGX's Interest Expenses over 5 years: stood at $556000.0 in 2021, then grew by 21.4% to $675000.0 in 2022, then sank by 344.0% to -$1.6 million in 2023, then soared by 151.06% to $841000.0 in 2024, then soared by 59507.61% to $501.3 million in 2025.
  • Business Quant data shows PTGX's Interest Expenses at $501.3 million in Q4 2025, $841000.0 in Q4 2024, and $1.9 million in Q3 2024.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Int Expense (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -42,141.15
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - 100,000.00
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 32.89 Mn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 420.30 Mn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 28.30 Mn
7 Belite Bio 61.40 Bn 61.40 Bn - -
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn -
9 Revolution Medicines 37.37 Bn 37.37 Bn - 1.17 Bn
10 Protagonist Therapeutics 8.88 Bn 8.88 Bn - -

Historic Data

Download Data
DateValue
Dec 31, 2025 501.30 Mn
Dec 31, 2025 501.30 Mn
Dec 31, 2024 841,000.00
Dec 31, 2024 841,000.00
Sep 30, 2024 1.92 Mn
Sep 30, 2024 1.92 Mn
Jun 30, 2024 2.07 Mn
Jun 30, 2024 2.07 Mn
Mar 31, 2024 696,000.00
Mar 31, 2024 696,000.00
Dec 31, 2023 -1.65 Mn
Dec 31, 2023 -1.65 Mn
Sep 30, 2023 693,000.00
Sep 30, 2023 693,000.00
Jun 30, 2023 92.20 Mn
Jun 30, 2023 92.20 Mn
Mar 31, 2023 63.30 Mn
Mar 31, 2023 63.30 Mn
Dec 31, 2022 675,000.00
Dec 31, 2022 675,000.00