Protagonist Therapeutics PTGX
NASDAQ PTGX
$145.65 -3.15 (-2.12%)
As of: Sep 4, 2026 · 3:59 PM EDT

Protagonist Therapeutics (PTGX) FCF Margin (2017 - 2026)

Protagonist Therapeutics (PTGX) posted FCF Margin of 87.02% for Q1 2026, up 83.21% sequentially from 518.45% in Q4 2025, and down 52775.0% YoY from N/an in Q1 2025.

Analysis

Protagonist Therapeutics (PTGX) FCF Margin (2017 - 2026) Analysis & Trends

Protagonist Therapeutics has reported FCF Margin for 10 years, with the latest figure at 87.02% in Q1 2026.

  • Quarterly FCF Margin fell 52775.0% year-over-year to 87.02% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 159.04% (down 32489.0% YoY) and the FY2025 annual result came in at 121.87%, up 7980.0% from the prior year.
  • FCF Margin rose to 87.02% in Q1 2026 per PTGX's latest filing, from 518.45% in the prior quarter.
  • Over five years, FCF Margin peaked at 6445.62% in Q2 2024 and troughed at 1621.07% in Q2 2022.
  • A 5-year average of 279.58% and a median of 63.06% in 2025 frame the typical range for FCF Margin.
  • The widest YoY moves for FCF Margin: up 57338 bps in 2025, down 695658 bps in 2025.
  • Over 5 years, FCF Margin stood at 1621.07% in 2022, then soared by 102 bps to 33.88% in 2023, then slumped by 153 bps to 17.87% in 2024, then sank by 2801 bps to 518.45% in 2025, then soared by 83 bps to 87.02% in 2026.
  • According to Business Quant data, FCF Margin over the past three periods registered 87.02%, 518.45%, and 39.09% for Q1 2026, Q4 2025, and Q3 2025 respectively.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) FCF Margin (Qtr)
1 Vertex Pharmaceuticals 138.47 Bn 130.62 Bn 2.84 Bn 30.39%
2 Regeneron Pharmaceuticals 85.18 Bn 77.19 Bn 3.93 Bn 13.35%
3 Argenx Se 63.38 Bn 58.19 Bn 1.37 Bn -
4 Moderna 58.09 Bn 52.95 Bn 52.00 Mn -388.28%
5 Revolution Medicines 44.33 Bn 44.33 Bn - -
6 BeOne Medicines 40.02 Bn 34.92 Bn 1.53 Bn 25.68%
7 Alnylam Pharmaceuticals 35.57 Bn 32.27 Bn 992.69 Mn 22.62%
8 Royalty Pharma 28.45 Bn 27.61 Bn - 70.82%
9 Insmed 27.48 Bn 26.32 Bn 358.27 Mn -22.35%
10 Protagonist Therapeutics 9.61 Bn 9.61 Bn - 102.32%
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 102.32%
Mar 31, 2026 -87.21%
Dec 31, 2025 -499.11%
Sep 30, 2025 -42.98%
Jun 30, 2025 -533.59%
Mar 31, 2025 440.73%
Dec 31, 2024 -17.87%
Sep 30, 2024 -612.47%
Jun 30, 2024 6,445.62%
Mar 31, 2024 -10.85%
Dec 31, 2023 33.88%
Dec 31, 2022 166,868.42%
Jun 30, 2022 -1,547.22%
Mar 31, 2022 -147.50%
Dec 31, 2021 -314.90%
Sep 30, 2021 -279.36%
Jun 30, 2021 -1,068.43%
Mar 31, 2021 -466.89%
Dec 31, 2020 -336.14%
Sep 30, 2020 -124.77%