Protagonist Therapeutics (PTGX) FCF Margin (2017 - 2026)

Protagonist Therapeutics (PTGX) reported FCF Margin of 87.02% for Q1 2026, down 52775.0% on a YoY basis from N/an in Q1 2025, and up 83.21% sequentially from 518.45% in Q4 2025.

Protagonist Therapeutics (PTGX) FCF Margin (2017 - 2026) Analysis & Trends

Protagonist Therapeutics (PTGX) has 10 years of FCF Margin data on file, last reported at 87.02% in Q1 2026.

  • For the quarter ending Q1 2026, FCF Margin fell 52775.0% year-over-year to 87.02%; the trailing twelve-month figure through Mar 2026 stood at 159.04% (down 32489.0% YoY), and the FY2025 full-year result was 121.87%, up 7980.0% from the prior year.
  • FCF Margin rose to 87.02% in Q1 2026, from 518.45% in the prior quarter.
  • In the past five years, FCF Margin ranged from a high of 6445.62% in Q2 2024 to a low of 1621.07% in Q2 2022.
  • A 5-year average of 279.58% and a median of 63.06% in 2025 frame the typical range for FCF Margin.
  • Peak annual rise in FCF Margin reached 57338 bps in 2025, while the deepest fall reached 695658 bps in 2025.
  • Tracing PTGX's FCF Margin over 5 years: stood at 1621.07% in 2022, then soared by 102 bps to 33.88% in 2023, then tumbled by 153 bps to 17.87% in 2024, then slumped by 2801 bps to 518.45% in 2025, then soared by 83 bps to 87.02% in 2026.
  • Business Quant data shows PTGX's FCF Margin at 87.02% in Q1 2026, 518.45% in Q4 2025, and 39.09% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) FCF Margin (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 10.45%
4 NuCana 279.75 Bn 279.75 Bn - -
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 43.35%
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 23.53%
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -
9 Revolution Medicines 37.78 Bn 37.78 Bn - -
10 Protagonist Therapeutics 8.81 Bn 8.81 Bn - -87.02%

Historic Data

Download Data
DateValue
Mar 31, 2026 -87.02%
Dec 31, 2025 -518.45%
Sep 30, 2025 -39.09%
Jun 30, 2025 -510.96%
Mar 31, 2025 440.73%
Dec 31, 2024 -17.87%
Sep 30, 2024 -612.47%
Jun 30, 2024 6,445.62%
Mar 31, 2024 -10.85%
Dec 31, 2023 33.88%
Jun 30, 2022 -1,621.07%
Mar 31, 2022 -147.50%
Dec 31, 2021 -314.01%
Sep 30, 2021 -270.80%
Jun 30, 2021 -1,070.33%
Mar 31, 2021 -466.20%
Dec 31, 2020 -336.14%
Sep 30, 2020 -124.77%
Jun 30, 2020 -347.68%
Mar 31, 2020 -438.33%