Protagonist Therapeutics (PTGX) FCF Margin (2017 - 2026)

Protagonist Therapeutics' (PTGX) quarterly FCF Margin came in at 87.21% in Q1 2026, down 52974.0% year-on-year from N/an in Q1 2025, and up 83.18% quarter-over-quarter from 518.45% in Q4 2025.

Protagonist Therapeutics (PTGX) FCF Margin (2017 - 2026) Analysis & Trends

Protagonist Therapeutics has disclosed FCF Margin across 10 years of filings, most recently posting 87.21% for Q1 2026.

  • FCF Margin for Q1 2026 came in at 87.21%, down 52974.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 159.87% (down 32588.0% YoY), and the FY2025 annual result was 121.87%, up 7980.0% from the prior year.
  • FCF Margin came in at 87.21% for Q1 2026 at Protagonist Therapeutics, up from 518.45% in the prior quarter.
  • In the past five years, FCF Margin ranged from a high of 166868.42% in Q4 2022 to a low of 1621.07% in Q2 2022.
  • The 5-year median for FCF Margin is 18.31% (2024), against an average of 13105.05%.
  • Across the five-year window, FCF Margin surged 16718243 bps in 2022 and tumbled 16669901 bps in 2023, its largest moves.
  • Protagonist Therapeutics' FCF Margin stood at 166868.42% in 2022, then sank by 100 bps to 169.41% in 2023, then tumbled by 111 bps to 18.31% in 2024, then plunged by 2732 bps to 518.45% in 2025, then soared by 83 bps to 87.21% in 2026.
  • The last three FCF Margin figures came in at 87.21% (Q1 2026), 518.45% (Q4 2025), and 12.46% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) FCF Margin (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -3.98%
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 43.35%
9 Abivax 91.96 Bn 91.96 Bn - -
10 Protagonist Therapeutics 7.35 Bn 7.35 Bn - -87.21%

Historic Data

Download Data
DateValue
Mar 31, 2026 -87.21%
Dec 31, 2025 -518.45%
Sep 30, 2025 -12.46%
Jun 30, 2025 -542.82%
Mar 31, 2025 442.53%
Dec 31, 2024 -18.31%
Sep 30, 2024 -597.07%
Jun 30, 2024 6,440.89%
Mar 31, 2024 -10.78%
Dec 31, 2023 169.41%
Dec 31, 2022 166,868.42%
Jun 30, 2022 -1,621.07%
Mar 31, 2022 -147.50%
Dec 31, 2021 -314.01%
Sep 30, 2021 -270.80%
Jun 30, 2021 -1,070.33%
Mar 31, 2021 -466.20%
Dec 31, 2020 -334.96%
Sep 30, 2020 -124.24%
Mar 31, 2019 -1,078.72%