Protagonist Therapeutics (PTGX) Enterprise Value (2015 - 2026)

Protagonist Therapeutics' (PTGX) quarterly Enterprise Value came in at -$547.8 million in Q1 2026, up 4.63% year-on-year from -$523.6 million in Q1 2025, and up 3.45% quarter-over-quarter from -$567.4 million in Q4 2025.

Protagonist Therapeutics (PTGX) Enterprise Value (2015 - 2026) Analysis & Trends

Protagonist Therapeutics has disclosed Enterprise Value across 12 years of filings, most recently posting -$547.8 million for Q1 2026.

  • Enterprise Value for Q1 2026 came in at -$547.8 million, up 4.63% year-over-year; the trailing twelve-month figure through Mar 2026 was -$547.8 million (up 4.63% YoY), and the FY2025 annual result was -$567.4 million, down 35.44% from the prior year.
  • Enterprise Value came in at -$547.8 million for Q1 2026 at Protagonist Therapeutics, up from -$567.4 million in the prior quarter.
  • In the past five years, Enterprise Value ranged from a high of -$230.8 million in Q1 2023 to a low of -$576.1 million in Q3 2025.
  • The 5-year median for Enterprise Value is -$341.6 million (2023), against an average of -$407.0 million.
  • Across the five-year window, Enterprise Value advanced 27.39% in 2022 and tumbled 79.99% in 2024, its largest moves.
  • Protagonist Therapeutics' Enterprise Value stood at -$237.4 million in 2022, then plunged by 43.93% to -$341.6 million in 2023, then declined by 22.63% to -$418.9 million in 2024, then tumbled by 35.44% to -$567.4 million in 2025, then gained by 3.45% to -$547.8 million in 2026.
  • The last three Enterprise Value figures came in at -$547.8 million (Q1 2026), -$567.4 million (Q4 2025), and -$576.1 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -32.30 Mn
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -4.14 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -286.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -18.44 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -2.77 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -7.20 Mn
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn -7.25 Bn
9 Abivax 91.96 Bn 91.96 Bn - -584.73 Mn
10 Protagonist Therapeutics 7.35 Bn 7.35 Bn - -547.79 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -547.79 Mn
Dec 31, 2025 -567.36 Mn
Sep 30, 2025 -576.12 Mn
Jun 30, 2025 -570.47 Mn
Mar 31, 2025 -574.36 Mn
Dec 31, 2024 -418.91 Mn
Sep 30, 2024 -468.72 Mn
Jun 30, 2024 -564.04 Mn
Mar 31, 2024 -322.64 Mn
Dec 31, 2023 -341.62 Mn
Sep 30, 2023 -320.75 Mn
Jun 30, 2023 -313.38 Mn
Mar 31, 2023 -230.79 Mn
Dec 31, 2022 -237.36 Mn
Sep 30, 2022 -267.42 Mn
Jun 30, 2022 -291.89 Mn
Mar 31, 2022 -305.29 Mn
Dec 31, 2021 -326.90 Mn
Sep 30, 2021 -314.30 Mn
Jun 30, 2021 -192.64 Mn