Protagonist Therapeutics (PTGX) Enterprise Value (2015 - 2026)

Protagonist Therapeutics (PTGX) reported Enterprise Value of -$547.8 million for Q1 2026, up 4.62% on a YoY basis from -$523.6 million in Q1 2025, and up 3.45% sequentially from -$567.4 million in Q4 2025.

Protagonist Therapeutics (PTGX) Enterprise Value (2015 - 2026) Analysis & Trends

Protagonist Therapeutics (PTGX) has 12 years of Enterprise Value data on file, last reported at -$547.8 million in Q1 2026.

  • For the quarter ending Q1 2026, Enterprise Value rose 4.62% year-over-year to -$547.8 million; the trailing twelve-month figure through Mar 2026 stood at -$547.8 million (up 4.62% YoY), and the FY2025 full-year result was -$567.4 million, down 35.44% from the prior year.
  • Enterprise Value grew to -$547.8 million in Q1 2026, from -$567.4 million in the prior quarter.
  • In the past five years, Enterprise Value ranged from a high of -$120.5 million in Q2 2022 to a low of -$576.1 million in Q3 2025.
  • A 5-year average of -$396.9 million and a median of -$341.6 million in 2023 frame the typical range for Enterprise Value.
  • Across the five-year window, Enterprise Value surged 37.47% in 2022 and slumped 160.15% in 2023, its largest moves.
  • Tracing PTGX's Enterprise Value over 5 years: stood at -$237.3 million in 2022, then tumbled by 43.94% to -$341.6 million in 2023, then decreased by 22.62% to -$418.9 million in 2024, then plunged by 35.44% to -$567.4 million in 2025, then advanced by 3.45% to -$547.8 million in 2026.
  • Business Quant data shows PTGX's Enterprise Value at -$547.8 million in Q1 2026, -$567.4 million in Q4 2025, and -$576.1 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -283.54 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -61.40 Mn
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn -4.79 Bn
4 NuCana 279.75 Bn 279.75 Bn - -32.26 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn -7.25 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn -8.75 Bn
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -5.18 Bn
9 Revolution Medicines 37.78 Bn 37.78 Bn - -1.91 Bn
10 Protagonist Therapeutics 8.81 Bn 8.81 Bn - -547.81 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -547.81 Mn
Dec 31, 2025 -567.39 Mn
Sep 30, 2025 -576.12 Mn
Jun 30, 2025 -570.47 Mn
Mar 31, 2025 -574.35 Mn
Dec 31, 2024 -418.91 Mn
Sep 30, 2024 -468.72 Mn
Jun 30, 2024 -564.00 Mn
Mar 31, 2024 -322.67 Mn
Dec 31, 2023 -341.63 Mn
Sep 30, 2023 -320.75 Mn
Jun 30, 2023 -313.38 Mn
Mar 31, 2023 -230.79 Mn
Dec 31, 2022 -237.34 Mn
Sep 30, 2022 -267.44 Mn
Jun 30, 2022 -120.46 Mn
Mar 31, 2022 -305.29 Mn
Dec 31, 2021 -326.90 Mn
Sep 30, 2021 -314.30 Mn
Jun 30, 2021 -192.64 Mn