Protagonist Therapeutics (PTGX) Enterprise Value (2017 - 2025)

Protagonist Therapeutics' Enterprise Value history spans 9 years, with the latest figure at -$567.4 million for Q4 2025.

  • For Q4 2025, Enterprise Value fell 35.44% year-over-year to -$567.4 million; the TTM value through Dec 2025 reached -$567.4 million, down 35.44%, while the annual FY2025 figure was -$567.4 million, 35.44% down from the prior year.
  • Enterprise Value for Q4 2025 was -$567.4 million at Protagonist Therapeutics, up from -$576.1 million in the prior quarter.
  • Across five years, Enterprise Value topped out at -$120.5 million in Q2 2022 and bottomed at -$576.1 million in Q3 2025.
  • The 5-year median for Enterprise Value is -$321.7 million (2023), against an average of -$365.3 million.
  • The largest annual shift saw Enterprise Value tumbled 354.09% in 2021 before it soared 37.47% in 2022.
  • A 5-year view of Enterprise Value shows it stood at -$326.9 million in 2021, then rose by 27.38% to -$237.4 million in 2022, then crashed by 43.93% to -$341.6 million in 2023, then dropped by 22.62% to -$418.9 million in 2024, then tumbled by 35.44% to -$567.4 million in 2025.
  • Per Business Quant, the three most recent readings for PTGX's Enterprise Value are -$567.4 million (Q4 2025), -$576.1 million (Q3 2025), and -$570.5 million (Q2 2025).