Protagonist Therapeutics PTGX
NASDAQ PTGX
$145.65 -3.15 (-2.12%)
As of: Sep 4, 2026 · 3:59 PM EDT

Protagonist Therapeutics (PTGX) Enterprise Value (2016 - 2026)

Protagonist Therapeutics (PTGX) posted Enterprise Value of -$547.8 million for Q1 2026, up 3.45% sequentially from -$567.4 million in Q4 2025, and up 4.62% YoY from -$523.6 million in Q1 2025.

Analysis

Protagonist Therapeutics (PTGX) Enterprise Value (2016 - 2026) Analysis & Trends

Protagonist Therapeutics has reported Enterprise Value for 12 years, with the latest figure at -$547.8 million in Q1 2026.

  • Quarterly Enterprise Value rose 4.62% year-over-year to -$547.8 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$547.8 million (up 4.62% YoY) and the FY2025 annual result came in at -$567.4 million, down 35.44% from the prior year.
  • Enterprise Value grew to -$547.8 million in Q1 2026 per PTGX's latest filing, from -$567.4 million in the prior quarter.
  • Over five years, Enterprise Value peaked at -$120.5 million in Q2 2022 and troughed at -$576.1 million in Q3 2025.
  • A 5-year average of -$396.9 million and a median of -$341.6 million in 2023 frame the typical range for Enterprise Value.
  • The sharpest annual moves came in 2022 and 2023: Enterprise Value jumped 37.47% in 2022, then plunged 160.15% in 2023.
  • Over 5 years, Enterprise Value stood at -$237.3 million in 2022, then slumped by 43.94% to -$341.6 million in 2023, then declined by 22.62% to -$418.9 million in 2024, then tumbled by 35.44% to -$567.4 million in 2025, then increased by 3.45% to -$547.8 million in 2026.
  • According to Business Quant data, Enterprise Value over the past three periods registered -$547.8 million, -$567.4 million, and -$576.1 million for Q1 2026, Q4 2025, and Q3 2025 respectively.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Vertex Pharmaceuticals 138.47 Bn 130.62 Bn 2.84 Bn
2 Regeneron Pharmaceuticals 85.18 Bn 77.19 Bn 3.93 Bn
3 Argenx Se 63.38 Bn 58.19 Bn 1.37 Bn
4 Moderna 58.09 Bn 52.95 Bn 52.00 Mn
5 Revolution Medicines 44.33 Bn 44.33 Bn -
6 BeOne Medicines 40.02 Bn 34.92 Bn 1.53 Bn
7 Alnylam Pharmaceuticals 35.57 Bn 32.27 Bn 992.69 Mn
8 Royalty Pharma 28.45 Bn 27.61 Bn -
9 Insmed 27.48 Bn 26.32 Bn 358.27 Mn
10 Protagonist Therapeutics 9.61 Bn 9.61 Bn -
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 7.14 Bn
Mar 31, 2026 6.22 Bn
Dec 31, 2025 4.90 Bn
Sep 30, 2025 3.57 Bn
Jun 30, 2025 2.86 Bn
Mar 31, 2025 2.42 Bn
Dec 31, 2024 1.94 Bn
Sep 30, 2024 2.21 Bn
Jun 30, 2024 1.47 Bn
Mar 31, 2024 1.37 Bn
Dec 31, 2023 981.63 Mn
Sep 30, 2023 640.81 Mn
Jun 30, 2023 1.27 Bn
Mar 31, 2023 952.35 Mn
Dec 31, 2022 300.94 Mn
Sep 30, 2022 147.31 Mn
Jun 30, 2022 93.15 Mn
Mar 31, 2022 844.42 Mn
Dec 31, 2021 1.31 Bn
Sep 30, 2021 530.40 Mn