Protagonist Therapeutics (PTGX) Enterprise Value (2015 - 2026)
Protagonist Therapeutics' (PTGX) quarterly Enterprise Value came in at -$547.8 million in Q1 2026, up 4.63% year-on-year from -$523.6 million in Q1 2025, and up 3.45% quarter-over-quarter from -$567.4 million in Q4 2025.
Protagonist Therapeutics (PTGX) Enterprise Value (2015 - 2026) Analysis & Trends
Protagonist Therapeutics has disclosed Enterprise Value across 12 years of filings, most recently posting -$547.8 million for Q1 2026.
- Enterprise Value for Q1 2026 came in at -$547.8 million, up 4.63% year-over-year; the trailing twelve-month figure through Mar 2026 was -$547.8 million (up 4.63% YoY), and the FY2025 annual result was -$567.4 million, down 35.44% from the prior year.
- Enterprise Value came in at -$547.8 million for Q1 2026 at Protagonist Therapeutics, up from -$567.4 million in the prior quarter.
- In the past five years, Enterprise Value ranged from a high of -$230.8 million in Q1 2023 to a low of -$576.1 million in Q3 2025.
- The 5-year median for Enterprise Value is -$341.6 million (2023), against an average of -$407.0 million.
- Across the five-year window, Enterprise Value advanced 27.39% in 2022 and tumbled 79.99% in 2024, its largest moves.
- Protagonist Therapeutics' Enterprise Value stood at -$237.4 million in 2022, then plunged by 43.93% to -$341.6 million in 2023, then declined by 22.63% to -$418.9 million in 2024, then tumbled by 35.44% to -$567.4 million in 2025, then gained by 3.45% to -$547.8 million in 2026.
- The last three Enterprise Value figures came in at -$547.8 million (Q1 2026), -$567.4 million (Q4 2025), and -$576.1 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Enterprise Value (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | -32.30 Mn |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | -4.14 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -286.70 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | -18.44 Mn |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | -2.77 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | -7.20 Mn |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | -7.25 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -584.73 Mn |
| 10 | Protagonist Therapeutics | 7.35 Bn | 7.35 Bn | - | -547.79 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -547.79 Mn |
| Dec 31, 2025 | -567.36 Mn |
| Sep 30, 2025 | -576.12 Mn |
| Jun 30, 2025 | -570.47 Mn |
| Mar 31, 2025 | -574.36 Mn |
| Dec 31, 2024 | -418.91 Mn |
| Sep 30, 2024 | -468.72 Mn |
| Jun 30, 2024 | -564.04 Mn |
| Mar 31, 2024 | -322.64 Mn |
| Dec 31, 2023 | -341.62 Mn |
| Sep 30, 2023 | -320.75 Mn |
| Jun 30, 2023 | -313.38 Mn |
| Mar 31, 2023 | -230.79 Mn |
| Dec 31, 2022 | -237.36 Mn |
| Sep 30, 2022 | -267.42 Mn |
| Jun 30, 2022 | -291.89 Mn |
| Mar 31, 2022 | -305.29 Mn |
| Dec 31, 2021 | -326.90 Mn |
| Sep 30, 2021 | -314.30 Mn |
| Jun 30, 2021 | -192.64 Mn |