Protagonist Therapeutics (PTGX) EBT Margin (2017 - 2026)

Protagonist Therapeutics (PTGX) reported EBT Margin of 4.05% for Q1 2026, up 4520.0% on a YoY basis from 0.09% in Q1 2025, and up 100.69% sequentially from 587.84% in Q4 2025.

Protagonist Therapeutics (PTGX) EBT Margin (2017 - 2026) Analysis & Trends

Protagonist Therapeutics (PTGX) has 10 years of EBT Margin data on file, last reported at 4.05% in Q1 2026.

  • For the quarter ending Q1 2026, EBT Margin rose 4520.0% year-over-year to 4.05%; the trailing twelve-month figure through Mar 2026 stood at 155.78% (down 18400.0% YoY), and the FY2025 full-year result was 281.01%, down 34532.0% from the prior year.
  • EBT Margin advanced to 4.05% in Q1 2026, from 587.84% in the prior quarter.
  • In the past five years, EBT Margin ranged from a high of 82.63% in Q1 2024 to a low of 4966.12% in Q2 2022.
  • A 5-year average of 713.51% and a median of 424.05% in 2022 frame the typical range for EBT Margin.
  • Peak annual rise in EBT Margin reached 12750 bps in 2022, while the deepest fall reached 360445 bps in 2022.
  • Tracing PTGX's EBT Margin over 5 years: stood at 4966.12% in 2022, then surged by 101 bps to 54.67% in 2023, then jumped by 48 bps to 80.99% in 2024, then tumbled by 826 bps to 587.84% in 2025, then soared by 101 bps to 4.05% in 2026.
  • Business Quant data shows PTGX's EBT Margin at 4.05% in Q1 2026, 587.84% in Q4 2025, and 834.87% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBT Margin (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 17.13%
4 NuCana 279.75 Bn 279.75 Bn - -
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 41.95%
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 23.05%
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 34.77%
9 Revolution Medicines 37.78 Bn 37.78 Bn - -
10 Protagonist Therapeutics 8.81 Bn 8.81 Bn - 4.05%

Historic Data

Download Data
DateValue
Mar 31, 2026 4.05%
Dec 31, 2025 -587.84%
Sep 30, 2025 -834.87%
Jun 30, 2025 -623.86%
Mar 31, 2025 -41.15%
Dec 31, 2024 80.99%
Sep 30, 2024 -719.36%
Jun 30, 2024 -750.95%
Mar 31, 2024 82.63%
Dec 31, 2023 54.67%
Jun 30, 2022 -4,966.12%
Mar 31, 2022 -260.26%
Dec 31, 2021 -428.30%
Sep 30, 2021 -328.64%
Jun 30, 2021 -1,361.68%
Mar 31, 2021 -387.75%
Dec 31, 2020 -334.27%
Sep 30, 2020 -59.20%
Jun 30, 2020 -294.23%
Mar 31, 2020 -545.76%