Protagonist Therapeutics (PTGX) EBT Margin (2017 - 2026)

Protagonist Therapeutics' (PTGX) quarterly EBT Margin came in at 4.05% in Q1 2026, up 4520.0% year-on-year from 0.09% in Q1 2025, and up 100.69% quarter-over-quarter from 587.84% in Q4 2025.

Protagonist Therapeutics (PTGX) EBT Margin (2017 - 2026) Analysis & Trends

Protagonist Therapeutics has disclosed EBT Margin across 10 years of filings, most recently posting 4.05% for Q1 2026.

  • EBT Margin for Q1 2026 came in at 4.05%, up 4520.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 155.78% (down 4582.0% YoY), and the FY2025 annual result was 281.01%, down 28102.0% from the prior year.
  • EBT Margin came in at 4.05% for Q1 2026 at Protagonist Therapeutics, up from 587.84% in the prior quarter.
  • In the past five years, EBT Margin ranged from a high of 180342.11% in Q4 2022 to a low of 4768.22% in Q2 2022.
  • The 5-year median for EBT Margin is 88.31% (2024), against an average of 13246.63%.
  • Across the five-year window, EBT Margin surged 18077041 bps in 2022 and plunged 18006876 bps in 2023, its largest moves.
  • Protagonist Therapeutics' EBT Margin stood at 180342.11% in 2022, then sank by 100 bps to 273.35% in 2023, then tumbled by 132 bps to 88.31% in 2024, then tumbled by 566 bps to 587.84% in 2025, then jumped by 101 bps to 4.05% in 2026.
  • The last three EBT Margin figures came in at 4.05% (Q1 2026), 587.84% (Q4 2025), and 834.87% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBT Margin (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 6.40%
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 41.95%
9 Abivax 91.96 Bn 91.96 Bn - -
10 Protagonist Therapeutics 7.35 Bn 7.35 Bn - 4.05%

Historic Data

Download Data
DateValue
Mar 31, 2026 4.05%
Dec 31, 2025 -587.84%
Sep 30, 2025 -834.87%
Jun 30, 2025 -623.86%
Mar 31, 2025 -41.15%
Dec 31, 2024 -88.31%
Sep 30, 2024 -719.36%
Jun 30, 2024 -750.95%
Mar 31, 2024 82.63%
Dec 31, 2023 273.35%
Dec 31, 2022 180,342.11%
Jun 30, 2022 -4,768.22%
Mar 31, 2022 -81.42%
Dec 31, 2021 -428.30%
Sep 30, 2021 -328.64%
Jun 30, 2021 -1,361.68%
Mar 31, 2021 -387.75%
Dec 31, 2020 -444.50%
Sep 30, 2020 -59.20%
Mar 31, 2019 -892.31%