Protagonist Therapeutics (PTGX) EBT (2015 - 2026)

Protagonist Therapeutics (PTGX) posted EBT of $2.3 million for Q1 2026, up 105.22% sequentially from -$43.7 million in Q4 2025, and up 119.57% YoY from $1.0 million in Q1 2025.

Protagonist Therapeutics (PTGX) EBT (2015 - 2026) Analysis & Trends

Protagonist Therapeutics has reported EBT for 12 years, with the latest figure at $2.3 million in Q1 2026.

  • Quarterly EBT rose 119.57% year-over-year to $2.3 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$115.4 million (down 302.21% YoY) and the FY2025 annual result came in at -$129.3 million, down 146.29% from the prior year.
  • EBT grew to $2.3 million in Q1 2026 per PTGX's latest filing, from -$43.7 million in the prior quarter.
  • Over five years, EBT peaked at $210.7 million in Q1 2024 and troughed at -$66.9 million in Q1 2022.
  • A 5-year average of -$6.2 million and a median of -$33.7 million in 2023 frame the typical range for EBT.
  • The sharpest annual moves came in 2022 and 2024: EBT tumbled 178.95% in 2022, then surged 724.66% in 2024.
  • Over 5 years, EBT stood at -$34.9 million in 2022, then jumped by 178.23% to $27.3 million in 2023, then soared by 388.88% to $133.6 million in 2024, then plunged by 132.71% to -$43.7 million in 2025, then jumped by 105.22% to $2.3 million in 2026.
  • According to Business Quant data, EBT over the past three periods registered $2.3 million, -$43.7 million, and -$39.3 million for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBT (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 1.39 Bn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 1.53 Bn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 541.00 Mn
4 Revolution Medicines 43.64 Bn 43.64 Bn - -644.37 Mn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 312.46 Mn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -2,828.29
7 Royalty Pharma 33.72 Bn 35.84 Bn - 81.49 Mn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 177.81 Mn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -11.37 Mn
10 Protagonist Therapeutics 10.03 Bn 10.03 Bn - 165.11 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 165.11 Mn
Mar 31, 2026 2.28 Mn
Dec 31, 2025 -43.72 Mn
Sep 30, 2025 -39.34 Mn
Jun 30, 2025 -34.60 Mn
Mar 31, 2025 -11.66 Mn
Dec 31, 2024 133.64 Mn
Sep 30, 2024 -33.63 Mn
Jun 30, 2024 -31.29 Mn
Mar 31, 2024 210.67 Mn
Dec 31, 2023 27.34 Mn
Sep 30, 2023 -34.11 Mn
Jun 30, 2023 -38.46 Mn
Mar 31, 2023 -33.73 Mn
Dec 31, 2022 -34.94 Mn
Sep 30, 2022 -33.45 Mn
Jun 30, 2022 -42.66 Mn
Mar 31, 2022 -66.94 Mn
Dec 31, 2021 -36.91 Mn
Sep 30, 2021 -33.80 Mn