Protagonist Therapeutics (PTGX) EBITDA Margin (2017 - 2025)

Protagonist Therapeutics (PTGX) has disclosed EBITDA Margin for 9 consecutive years, with 677.09% as the latest value for Q4 2025.

  • Quarterly EBITDA Margin fell 63625.0% to 677.09% in Q4 2025 from the year-ago period, while the trailing twelve-month figure was 343.63% through Dec 2025, down 35732.0% year-over-year, with the annual reading at 343.63% for FY2025, 35714.0% down from the prior year.
  • EBITDA Margin hit 677.09% in Q4 2025 for Protagonist Therapeutics, up from 985.17% in the prior quarter.
  • In the past five years, EBITDA Margin ranged from a high of 230.49% in Q4 2023 to a low of 4604.78% in Q2 2022.
  • Historically, EBITDA Margin has averaged 704.11% across 5 years, with a median of 408.85% in 2021.
  • Biggest five-year swings in EBITDA Margin: tumbled -1007971bps in 2021 and later surged 39711bps in 2022.
  • Year by year, EBITDA Margin stood at 429.57% in 2021, then skyrocketed by 92bps to 32.46% in 2022, then soared by 810bps to 230.49% in 2023, then plummeted by -118bps to 40.84% in 2024, then tumbled by -1558bps to 677.09% in 2025.
  • Business Quant data shows EBITDA Margin for PTGX at 677.09% in Q4 2025, 985.17% in Q3 2025, and 758.04% in Q2 2025.