Protagonist Therapeutics (PTGX) EBITDA Margin (2017 - 2026)
Protagonist Therapeutics' EBITDA Margin came in at 74.56% for Q2 2026, up 827.12 percentage points from -752.56% a year earlier and up 80.31 percentage points from the prior quarter.
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Analysis
Protagonist Therapeutics (PTGX) EBITDA Margin (2017 - 2026) Analysis & Trends
Over the trailing twelve months to Jun 30, 2026, Protagonist Therapeutics reported EBITDA Margin of 21.24%, up 9.35 percentage points year-over-year; for FY2025, it was -340.85%, down 399.24 percentage points from FY2024.
- EBITDA Margin carries a five-year change of -118.80 percentage points (FY2020 to FY2025).
- Going back by year, EBITDA Margin was 58.39% in FY2024 (+212.85 pp), -154.46% in FY2023 (+335.89 pp), -490.35% in FY2022 (-33.31 pp) and -457.04% in FY2021 (-234.99 pp).
- The Q2 2026 figure represents the highest quarterly EBITDA Margin since Q1 2024.
- Year-over-year, EBITDA Margin increased in four of the last seven quarters, with an average year-over-year change of +15.19 percentage points.
- The fastest year-over-year change in EBITDA Margin over five years came in Q2 2026 (a gain of 827.12 percentage points), and the weakest in Q2 2022 (a drop of 3220.72 percentage points).
- Business Quant data shows PTGX's EBITDA Margin at -5.75% (Q1 2026), -672.03% (Q4 2025) and -977.50% (Q3 2025) in the three quarters before Q2 2026.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 35.95% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 49.01% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | 6.02% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | - |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 33.11% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 46.01% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -124.26% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 39.16% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 39.10% |
| 10 | Protagonist Therapeutics | 9.21 Bn | 9.21 Bn | - | 74.56% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 74.56% |
| Mar 31, 2026 | -5.75% |
| Dec 31, 2025 | -672.03% |
| Sep 30, 2025 | -977.50% |
| Jun 30, 2025 | -752.56% |
| Mar 31, 2025 | -67.34% |
| Dec 31, 2024 | 74.37% |
| Sep 30, 2024 | -881.75% |
| Jun 30, 2024 | -925.17% |
| Mar 31, 2024 | 81.01% |
| Dec 31, 2023 | 38.83% |
| Jun 30, 2022 | -4,576.00% |
| Mar 31, 2022 | -81.11% |
| Dec 31, 2021 | -426.84% |
| Sep 30, 2021 | -327.76% |
| Jun 30, 2021 | -1,355.28% |
| Mar 31, 2021 | -385.22% |
| Dec 31, 2020 | -327.13% |
| Sep 30, 2020 | -57.88% |
| Jun 30, 2020 | -289.77% |
API Access
Protagonist Therapeutics EBITDA Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=ebitda-margin&ticker=PTGX&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "ebitda-margin", "ticker": "PTGX", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=ebitda-margin&ticker=PTGX&period=max&api_key=YOUR_API_KEY");
const data = await res.json();