Protagonist Therapeutics (PTGX) EBIT Margin (2017 - 2026)

Protagonist Therapeutics' (PTGX) quarterly EBIT Margin came in at 6.47% in Q1 2026, up 6171.0% year-on-year from 0.1% in Q1 2025, and up 99.04% quarter-over-quarter from 677.09% in Q4 2025.

Protagonist Therapeutics (PTGX) EBIT Margin (2017 - 2026) Analysis & Trends

Protagonist Therapeutics has disclosed EBIT Margin across 10 years of filings, most recently posting 6.47% for Q1 2026.

  • EBIT Margin for Q1 2026 came in at 6.47%, up 6171.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 192.36% (down 10978.0% YoY), and the FY2025 annual result was 343.63%, down 35714.0% from the prior year.
  • EBIT Margin came in at 6.47% for Q1 2026 at Protagonist Therapeutics, up from 677.09% in the prior quarter.
  • In the past five years, EBIT Margin ranged from a high of 192189.47% in Q4 2022 to a low of 4824.56% in Q2 2022.
  • The 5-year median for EBIT Margin is 82.07% (2022), against an average of 14154.73%.
  • Across the five-year window, EBIT Margin jumped 19261904 bps in 2022 and tumbled 19118826 bps in 2023, its largest moves.
  • Protagonist Therapeutics' EBIT Margin stood at 192189.47% in 2022, then slumped by 99 bps to 1001.21% in 2023, then tumbled by 104 bps to 40.84% in 2024, then tumbled by 1558 bps to 677.09% in 2025, then surged by 99 bps to 6.47% in 2026.
  • The last three EBIT Margin figures came in at 6.47% (Q1 2026), 677.09% (Q4 2025), and 985.17% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBIT Margin (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -6.43%
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 38.10%
9 Abivax 91.96 Bn 91.96 Bn - -
10 Protagonist Therapeutics 7.35 Bn 7.35 Bn - -6.47%

Historic Data

Download Data
DateValue
Mar 31, 2026 -6.47%
Dec 31, 2025 -677.09%
Sep 30, 2025 -985.17%
Jun 30, 2025 -758.04%
Mar 31, 2025 -68.18%
Dec 31, 2024 -40.84%
Sep 30, 2024 -886.70%
Jun 30, 2024 -930.96%
Mar 31, 2024 80.92%
Dec 31, 2023 1,001.21%
Dec 31, 2022 192,189.47%
Jun 30, 2022 -4,824.56%
Mar 31, 2022 -82.07%
Dec 31, 2021 -429.57%
Sep 30, 2021 -329.83%
Jun 30, 2021 -1,363.44%
Mar 31, 2021 -388.12%
Dec 31, 2020 -333.27%
Sep 30, 2020 -59.26%
Mar 31, 2019 -938.97%