Protagonist Therapeutics (PTGX) EBIT Margin (2017 - 2026)

Protagonist Therapeutics (PTGX) reported EBIT Margin of 6.47% for Q1 2026, up 6171.0% on a YoY basis from 0.1% in Q1 2025, and up 99.04% sequentially from 677.09% in Q4 2025.

Protagonist Therapeutics (PTGX) EBIT Margin (2017 - 2026) Analysis & Trends

Protagonist Therapeutics (PTGX) has 10 years of EBIT Margin data on file, last reported at 6.47% in Q1 2026.

  • For the quarter ending Q1 2026, EBIT Margin rose 6171.0% year-over-year to 6.47%; the trailing twelve-month figure through Mar 2026 stood at 192.36% (down 20582.0% YoY), and the FY2025 full-year result was 343.63%, down 40184.0% from the prior year.
  • EBIT Margin advanced to 6.47% in Q1 2026, from 677.09% in the prior quarter.
  • In the past five years, EBIT Margin ranged from a high of 80.92% in Q1 2024 to a low of 4824.56% in Q2 2022.
  • A 5-year average of 751.28% and a median of 379.58% in 2022 frame the typical range for EBIT Margin.
  • Peak annual rise in EBIT Margin reached 30605 bps in 2022, while the deepest fall reached 346112 bps in 2022.
  • Tracing PTGX's EBIT Margin over 5 years: stood at 4824.56% in 2022, then surged by 101 bps to 46.1% in 2023, then surged by 67 bps to 76.84% in 2024, then slumped by 981 bps to 677.09% in 2025, then jumped by 99 bps to 6.47% in 2026.
  • Business Quant data shows PTGX's EBIT Margin at 6.47% in Q1 2026, 677.09% in Q4 2025, and 985.17% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBIT Margin (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 16.51%
4 NuCana 279.75 Bn 279.75 Bn - -
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 38.10%
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 17.83%
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 31.68%
9 Revolution Medicines 37.78 Bn 37.78 Bn - -
10 Protagonist Therapeutics 8.81 Bn 8.81 Bn - -6.47%

Historic Data

Download Data
DateValue
Mar 31, 2026 -6.47%
Dec 31, 2025 -677.09%
Sep 30, 2025 -985.17%
Jun 30, 2025 -758.04%
Mar 31, 2025 -68.18%
Dec 31, 2024 76.84%
Sep 30, 2024 -886.70%
Jun 30, 2024 -930.96%
Mar 31, 2024 80.92%
Dec 31, 2023 46.10%
Jun 30, 2022 -4,824.56%
Mar 31, 2022 -82.07%
Dec 31, 2021 -429.57%
Sep 30, 2021 -329.83%
Jun 30, 2021 -1,363.44%
Mar 31, 2021 -388.12%
Dec 31, 2020 -333.27%
Sep 30, 2020 -59.26%
Jun 30, 2020 -293.02%
Mar 31, 2020 -540.09%