Protagonist Therapeutics (PTGX) EBIT (2015 - 2026)
Protagonist Therapeutics' (PTGX) quarterly EBIT came in at -$3.6 million in Q1 2026, up 81.11% year-on-year from -$2.0 million in Q1 2025, and up 92.76% quarter-over-quarter from -$50.4 million in Q4 2025.
Protagonist Therapeutics (PTGX) EBIT (2015 - 2026) Analysis & Trends
Protagonist Therapeutics has disclosed EBIT across 12 years of filings, most recently posting -$3.6 million for Q1 2026.
- EBIT for Q1 2026 came in at -$3.6 million, up 81.11% year-over-year; the trailing twelve-month figure through Mar 2026 was -$142.5 million (up 14.66% YoY), and the FY2025 annual result was -$158.1 million, down 369.49% from the prior year.
- EBIT came in at -$3.6 million for Q1 2026 at Protagonist Therapeutics, up from -$50.4 million in the prior quarter.
- In the past five years, EBIT ranged from a high of $206.3 million in Q1 2024 to a low of -$67.4 million in Q4 2024.
- The 5-year median for EBIT is -$38.3 million (2023), against an average of -$14.8 million.
- Peak annual rise in EBIT reached 672.75% in 2024, while the deepest fall reached 167.31% in 2024.
- Protagonist Therapeutics' EBIT stood at -$36.5 million in 2022, then surged by 374.18% to $100.1 million in 2023, then sank by 167.31% to -$67.4 million in 2024, then climbed by 25.27% to -$50.4 million in 2025, then surged by 92.76% to -$3.6 million in 2026.
- The last three EBIT figures came in at -$3.6 million (Q1 2026), -$50.4 million (Q4 2025), and -$46.4 million (Q3 2025), per Business Quant data.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBIT (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | -32.68 Mn |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | -2.97 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -19.70 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | -3.82 Mn |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | -15.76 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | -1.51 Mn |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 1.14 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -65.83 Mn |
| 10 | Protagonist Therapeutics | 7.35 Bn | 7.35 Bn | - | -3.65 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -3.65 Mn |
| Dec 31, 2025 | -50.36 Mn |
| Sep 30, 2025 | -46.42 Mn |
| Jun 30, 2025 | -42.04 Mn |
| Mar 31, 2025 | -19.31 Mn |
| Dec 31, 2024 | -67.39 Mn |
| Sep 30, 2024 | -41.45 Mn |
| Jun 30, 2024 | -38.79 Mn |
| Mar 31, 2024 | 206.31 Mn |
| Dec 31, 2023 | 100.12 Mn |
| Sep 30, 2023 | -38.33 Mn |
| Jun 30, 2023 | -42.35 Mn |
| Mar 31, 2023 | -36.02 Mn |
| Dec 31, 2022 | -36.52 Mn |
| Sep 30, 2022 | -32.30 Mn |
| Jun 30, 2022 | -41.44 Mn |
| Mar 31, 2022 | -21.11 Mn |
| Dec 31, 2021 | -37.02 Mn |
| Sep 30, 2021 | -33.93 Mn |
| Jun 30, 2021 | -30.88 Mn |