Protagonist Therapeutics (PTGX) EBIT (2015 - 2026)
Protagonist Therapeutics (PTGX) posted EBIT of -$3.6 million for Q1 2026, up 92.76% sequentially from -$50.4 million in Q4 2025, and up 81.11% YoY from -$2.0 million in Q1 2025.
Analysis
Protagonist Therapeutics (PTGX) EBIT (2015 - 2026) Analysis & Trends
Protagonist Therapeutics has reported EBIT for 12 years, with the latest figure at -$3.6 million in Q1 2026.
- Quarterly EBIT rose 81.11% year-over-year to -$3.6 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$142.5 million (down 623.31% YoY) and the FY2025 annual result came in at -$158.1 million, down 162.54% from the prior year.
- EBIT advanced to -$3.6 million in Q1 2026 per PTGX's latest filing, from -$50.4 million in the prior quarter.
- Over five years, EBIT peaked at $206.3 million in Q1 2024 and troughed at -$50.4 million in Q4 2025.
- A 5-year average of -$7.9 million and a median of -$36.5 million in 2022 frame the typical range for EBIT.
- The sharpest annual moves came in 2024 and 2025: EBIT surged 672.75% in 2024, then plunged 139.72% in 2025.
- Over 5 years, EBIT stood at -$36.5 million in 2022, then surged by 163.12% to $23.0 million in 2023, then surged by 450.05% to $126.8 million in 2024, then slumped by 139.72% to -$50.4 million in 2025, then jumped by 92.76% to -$3.6 million in 2026.
- According to Business Quant data, EBIT over the past three periods registered -$3.6 million, -$50.4 million, and -$46.4 million for Q1 2026, Q4 2025, and Q3 2025 respectively.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBIT (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 139.27 Bn | 131.42 Bn | 2.84 Bn | 1.25 Bn |
| 2 | Regeneron Pharmaceuticals | 85.55 Bn | 77.56 Bn | 3.93 Bn | 1.29 Bn |
| 3 | Argenx Se | 63.45 Bn | 58.27 Bn | 1.37 Bn | 493.00 Mn |
| 4 | Moderna | 57.73 Bn | 52.59 Bn | 52.00 Mn | -815.00 Mn |
| 5 | Revolution Medicines | 44.08 Bn | 44.08 Bn | - | -505.13 Mn |
| 6 | BeOne Medicines | 39.95 Bn | 34.85 Bn | 1.53 Bn | 325.05 Mn |
| 7 | Alnylam Pharmaceuticals | 35.14 Bn | 31.84 Bn | 992.69 Mn | 231.44 Mn |
| 8 | Royalty Pharma | 28.44 Bn | 27.60 Bn | - | 133.12 Mn |
| 9 | Insmed | 27.32 Bn | 26.16 Bn | 358.27 Mn | -1.55 Mn |
| 10 | Protagonist Therapeutics | 9.61 Bn | 9.61 Bn | - | 158.77 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 158.77 Mn |
| Mar 31, 2026 | -3.65 Mn |
| Dec 31, 2025 | -50.36 Mn |
| Sep 30, 2025 | -46.42 Mn |
| Jun 30, 2025 | -42.04 Mn |
| Mar 31, 2025 | -19.31 Mn |
| Dec 31, 2024 | 126.78 Mn |
| Sep 30, 2024 | -41.45 Mn |
| Jun 30, 2024 | -38.79 Mn |
| Mar 31, 2024 | 206.31 Mn |
| Dec 31, 2023 | 23.05 Mn |
| Sep 30, 2023 | -38.33 Mn |
| Jun 30, 2023 | -42.35 Mn |
| Mar 31, 2023 | -36.02 Mn |
| Dec 31, 2022 | -36.52 Mn |
| Sep 30, 2022 | -32.30 Mn |
| Jun 30, 2022 | -41.44 Mn |
| Mar 31, 2022 | -21.11 Mn |
| Dec 31, 2021 | -37.02 Mn |
| Sep 30, 2021 | -33.93 Mn |