Protagonist Therapeutics (PTGX) Change in Cash (2015 - 2026)

Protagonist Therapeutics (PTGX) reported Change in Cash of $65.3 million for Q1 2026, up 54.05% on a YoY basis from $42.4 million in Q1 2025, and up 345.07% sequentially from $14.7 million in Q4 2025.

Protagonist Therapeutics (PTGX) Change in Cash (2015 - 2026) Analysis & Trends

Protagonist Therapeutics (PTGX) has 12 years of Change in Cash data on file, last reported at $65.3 million in Q1 2026.

  • For the quarter ending Q1 2026, Change in Cash rose 54.05% year-over-year to $65.3 million; the trailing twelve-month figure through Mar 2026 stood at $54.1 million (up 264.43% YoY), and the FY2025 full-year result was $31.2 million, up 134.87% from the prior year.
  • Change in Cash improved to $65.3 million in Q1 2026, from $14.7 million in the prior quarter.
  • In the past five years, Change in Cash ranged from a high of $183.1 million in Q2 2024 to a low of -$224.5 million in Q3 2024.
  • A 5-year average of $4.1 million and a median of $1.9 million in 2023 frame the typical range for Change in Cash.
  • Across the five-year window, Change in Cash slumped 4524.55% in 2024 and jumped 399.48% in 2025, its largest moves.
  • Tracing PTGX's Change in Cash over 5 years: stood at -$27.1 million in 2022, then plunged by 61.79% to -$43.8 million in 2023, then increased by 22.67% to -$33.9 million in 2024, then soared by 143.33% to $14.7 million in 2025, then surged by 345.07% to $65.3 million in 2026.
  • Business Quant data shows PTGX's Change in Cash at $65.3 million in Q1 2026, $14.7 million in Q4 2025, and -$54.8 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Change in Cash (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -22.03 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -2.44 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 243.78 Mn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 417.10 Mn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn -153.10 Mn
7 Belite Bio 61.40 Bn 61.40 Bn - -
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn -
9 Revolution Medicines 37.37 Bn 37.37 Bn - 57.19 Mn
10 Protagonist Therapeutics 8.88 Bn 8.88 Bn - 65.32 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 65.32 Mn
Dec 31, 2025 14.68 Mn
Sep 30, 2025 -54.83 Mn
Jun 30, 2025 28.96 Mn
Mar 31, 2025 42.40 Mn
Dec 31, 2024 -33.87 Mn
Sep 30, 2024 -224.52 Mn
Jun 30, 2024 183.08 Mn
Mar 31, 2024 -14.16 Mn
Dec 31, 2023 -43.80 Mn
Sep 30, 2023 -4.86 Mn
Jun 30, 2023 107.70 Mn
Mar 31, 2023 1.94 Mn
Dec 31, 2022 -27.07 Mn
Sep 30, 2022 32.58 Mn
Jun 30, 2022 21.76 Mn
Mar 31, 2022 -25.19 Mn
Dec 31, 2021 3.12 Mn
Sep 30, 2021 -71.87 Mn
Jun 30, 2021 109.41 Mn