Protagonist Therapeutics (PTGX) Change in Cash (2015 - 2026)
Protagonist Therapeutics' (PTGX) quarterly Change in Cash came in at $65.3 million in Q1 2026, up 54.05% year-on-year from $42.4 million in Q1 2025, and up 345.07% quarter-over-quarter from $14.7 million in Q4 2025.
Protagonist Therapeutics (PTGX) Change in Cash (2015 - 2026) Analysis & Trends
Protagonist Therapeutics has disclosed Change in Cash across 12 years of filings, most recently posting $65.3 million for Q1 2026.
- Change in Cash for Q1 2026 came in at $65.3 million, up 54.05% year-over-year; the trailing twelve-month figure through Mar 2026 was $54.1 million (up 264.43% YoY), and the FY2025 annual result was $31.2 million, up 134.87% from the prior year.
- Change in Cash came in at $65.3 million for Q1 2026 at Protagonist Therapeutics, up from $14.7 million in the prior quarter.
- In the past five years, Change in Cash ranged from a high of $183.1 million in Q2 2024 to a low of -$224.5 million in Q3 2024.
- The 5-year median for Change in Cash is $1.9 million (2023), against an average of $4.1 million.
- Across the five-year window, Change in Cash plunged 4524.55% in 2024 and jumped 399.48% in 2025, its largest moves.
- Protagonist Therapeutics' Change in Cash stood at -$27.1 million in 2022, then tumbled by 61.79% to -$43.8 million in 2023, then rose by 22.67% to -$33.9 million in 2024, then jumped by 143.33% to $14.7 million in 2025, then soared by 345.07% to $65.3 million in 2026.
- The last three Change in Cash figures came in at $65.3 million (Q1 2026), $14.7 million (Q4 2025), and -$54.8 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Change in Cash (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | 2.44 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | 623.00 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | -2.44 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 417.10 Mn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -45.97 Mn |
| 10 | Protagonist Therapeutics | 7.35 Bn | 7.35 Bn | - | 65.32 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 65.32 Mn |
| Dec 31, 2025 | 14.68 Mn |
| Sep 30, 2025 | -54.83 Mn |
| Jun 30, 2025 | 28.96 Mn |
| Mar 31, 2025 | 42.40 Mn |
| Dec 31, 2024 | -33.87 Mn |
| Sep 30, 2024 | -224.52 Mn |
| Jun 30, 2024 | 183.08 Mn |
| Mar 31, 2024 | -14.16 Mn |
| Dec 31, 2023 | -43.80 Mn |
| Sep 30, 2023 | -4.86 Mn |
| Jun 30, 2023 | 107.70 Mn |
| Mar 31, 2023 | 1.94 Mn |
| Dec 31, 2022 | -27.07 Mn |
| Sep 30, 2022 | 32.58 Mn |
| Jun 30, 2022 | 21.76 Mn |
| Mar 31, 2022 | -25.19 Mn |
| Dec 31, 2021 | 3.12 Mn |
| Sep 30, 2021 | -71.87 Mn |
| Jun 30, 2021 | 109.41 Mn |