Personalis PSNL
NASDAQ PSNL
$16.78 -0.30 (-1.76%)
As of: Aug 27, 2026 · 3:59 PM EDT

Personalis (PSNL) Operating Income (2018 - 2026)

Personalis (PSNL) posted quarterly Operating Income of -$32.2 million for Q1 2026, down 81.74% year-over-year from -$176.1 million in Q1 2025, and down 27.29% quarter-over-quarter from -$25.3 million in Q4 2025.

Personalis (PSNL) Operating Income (2018 - 2026) Analysis & Trends

Personalis' Operating Income history runs 9 years deep, the most recent figure standing at -$32.2 million for Q1 2026.

  • In Q1 2026, Operating Income fell 81.74% year-over-year to -$32.2 million; the TTM figure through Mar 2026 stood at -$102.5 million (down 52.83% YoY), while the FY2025 annual figure was -$88.1 million, down 28.99% from the prior year.
  • Operating Income for Q1 2026 stood at -$32.2 million, down from -$25.3 million in the prior quarter.
  • The five-year high for Operating Income was -$14.4 million in Q3 2024, with the low at -$32.2 million in Q1 2026.
  • The 5-year median for Operating Income is -$25.3 million (2025), against an average of -$24.4 million.
  • The sharpest annual moves came in 2022 and 2024: Operating Income slumped 126.63% in 2022, then soared 53.29% in 2024.
  • Personalis' Operating Income stood at -$32.1 million in 2022, then advanced by 25.29% to -$24.0 million in 2023, then climbed by 24.45% to -$18.1 million in 2024, then sank by 39.5% to -$25.3 million in 2025, then declined by 27.29% to -$32.2 million in 2026.
  • Business Quant data shows PSNL's Operating Income at -$32.2 million in Q1 2026, -$25.3 million in Q4 2025, and -$23.3 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Thermo Fisher Scientific 234.15 Bn 230.09 Bn 8.34 Bn 2.09 Bn
2 Danaher 152.10 Bn 147.75 Bn 3.61 Bn 1.13 Bn
3 Natera 48.48 Bn 47.38 Bn 486.15 Mn -75.79 Mn
4 Agilent Technologies 44.35 Bn 42.55 Bn 990.00 Mn 399.00 Mn
5 Iqvia Holdings 43.68 Bn 41.60 Bn 1.44 Bn 506.00 Mn
6 Idexx Laboratories 43.02 Bn 42.83 Bn 779.09 Mn 425.57 Mn
7 Illumina 34.39 Bn 33.22 Bn 770.00 Mn 245.00 Mn
8 Mettler Toledo International 28.29 Bn 28.24 Bn 650.22 Mn 328.45 Mn
9 Labcorp Holdings 27.51 Bn 27.37 Bn 1.11 Bn 451.60 Mn
10 Personalis 1.78 Bn 1.56 Bn 4.74 Mn -33.59 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 -33.59 Mn
Mar 31, 2026 -32.16 Mn
Dec 31, 2025 -25.27 Mn
Sep 30, 2025 -23.29 Mn
Jun 30, 2025 -21.80 Mn
Mar 31, 2025 -17.70 Mn
Dec 31, 2024 -18.11 Mn
Sep 30, 2024 -14.38 Mn
Jun 30, 2024 -16.89 Mn
Mar 31, 2024 -18.88 Mn
Dec 31, 2023 -23.97 Mn
Sep 30, 2023 -30.79 Mn
Jun 30, 2023 -25.35 Mn
Mar 31, 2023 -29.83 Mn
Dec 31, 2022 -32.09 Mn
Sep 30, 2022 -27.26 Mn
Jun 30, 2022 -27.88 Mn
Mar 31, 2022 -28.31 Mn
Dec 31, 2021 -20.23 Mn
Sep 30, 2021 -17.69 Mn