Personalis (PSNL) Operating Income (2018 - 2026)
Personalis (PSNL) recorded quarterly Operating Income of -$32.2 million in Q1 2026, down 27.29% quarter-over-quarter from -$25.3 million in Q4 2025, and down 81.74% on a YoY basis from -$176.1 million in Q1 2025.
Personalis (PSNL) Operating Income (2018 - 2026) Analysis & Trends
Personalis' Operating Income history runs 9 years deep, the most recent figure standing at -$32.2 million for Q1 2026.
- In Q1 2026, Operating Income fell 81.74% year-over-year to -$32.2 million; the TTM figure through Mar 2026 stood at -$102.5 million (down 52.83% YoY), while the FY2025 annual figure was -$88.1 million, down 28.99% from the prior year.
- Operating Income was -$32.2 million for Q1 2026 at Personalis, down from -$25.3 million in the prior quarter.
- In the past five years, Operating Income ranged from a high of -$14.4 million in Q3 2024 to a low of -$32.2 million in Q1 2026.
- Historically, Operating Income has averaged -$24.4 million across 5 years, with a median of -$25.3 million in 2025.
- The sharpest annual moves came in 2022 and 2024: Operating Income tumbled 126.63% in 2022, then jumped 53.29% in 2024.
- A 5-year view of Operating Income shows it stood at -$32.1 million in 2022, then climbed by 25.29% to -$24.0 million in 2023, then grew by 24.45% to -$18.1 million in 2024, then slumped by 39.5% to -$25.3 million in 2025, then fell by 27.29% to -$32.2 million in 2026.
- The last three Operating Income figures came in at -$32.2 million (Q1 2026), -$25.3 million (Q4 2025), and -$23.3 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Op. Inc (Qtr) |
|---|---|---|---|---|---|
| 1 | Waters | 29,902.70 Bn | 29,902.24 Bn | 1.11 Bn | -47.00 Mn |
| 2 | Thermo Fisher Scientific | 175.99 Bn | 172.74 Bn | 7.74 Bn | 1.86 Bn |
| 3 | Danaher | 129.87 Bn | 124.18 Bn | 3.59 Bn | 1.34 Bn |
| 4 | Idexx Laboratories | 44.75 Bn | 44.55 Bn | 722.74 Mn | 362.59 Mn |
| 5 | Agilent Technologies | 37.52 Bn | 35.72 Bn | 990.00 Mn | 399.00 Mn |
| 6 | Iqvia Holdings | 30.91 Bn | 28.94 Bn | 1.36 Bn | 514.00 Mn |
| 7 | Natera | 30.21 Bn | 29.11 Bn | 696.04 Mn | -93.52 Mn |
| 8 | Illumina | 24.19 Bn | 23.04 Bn | 721.00 Mn | 209.00 Mn |
| 9 | Mettler Toledo International | 23.12 Bn | 23.06 Bn | 555.82 Mn | 238.95 Mn |
| 10 | Personalis | 1.05 Bn | 819.64 Mn | 281,000.00 | -32.16 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -32.16 Mn |
| Dec 31, 2025 | -25.27 Mn |
| Sep 30, 2025 | -23.29 Mn |
| Jun 30, 2025 | -21.80 Mn |
| Mar 31, 2025 | -17.70 Mn |
| Dec 31, 2024 | -18.11 Mn |
| Sep 30, 2024 | -14.38 Mn |
| Jun 30, 2024 | -16.89 Mn |
| Mar 31, 2024 | -18.88 Mn |
| Dec 31, 2023 | -23.97 Mn |
| Sep 30, 2023 | -30.79 Mn |
| Jun 30, 2023 | -25.35 Mn |
| Mar 31, 2023 | -29.83 Mn |
| Dec 31, 2022 | -32.09 Mn |
| Sep 30, 2022 | -27.26 Mn |
| Jun 30, 2022 | -27.88 Mn |
| Mar 31, 2022 | -28.31 Mn |
| Dec 31, 2021 | -20.23 Mn |
| Sep 30, 2021 | -17.69 Mn |
| Jun 30, 2021 | -14.95 Mn |