Growth Metrics

Personalis (PSNL) Operating Expenses (2018 - 2026)

Personalis has reported Operating Expenses over the past 8 years, most recently at $42.6 million for Q4 2025.

  • For Q4 2025, Operating Expenses rose 470.2% year-over-year to $42.6 million; the TTM value through Dec 2025 reached $127.2 million, up 30.97%, while the annual FY2025 figure was $157.7 million, 340.11% up from the prior year.
  • Operating Expenses for Q4 2025 was $42.6 million at Personalis, up from $7.2 million in the prior quarter.
  • Over five years, Operating Expenses peaked at $49.0 million in Q3 2023 and troughed at -$124.7 million in Q4 2023.
  • A 5-year average of $28.5 million and a median of $39.7 million in 2021 define the central range for Operating Expenses.
  • Biggest five-year swings in Operating Expenses: plummeted 355.42% in 2023 and later skyrocketed 470.2% in 2025.
  • Year by year, Operating Expenses stood at $40.9 million in 2021, then rose by 19.31% to $48.8 million in 2022, then tumbled by 355.42% to -$124.7 million in 2023, then skyrocketed by 105.99% to $7.5 million in 2024, then skyrocketed by 470.2% to $42.6 million in 2025.
  • Business Quant data shows Operating Expenses for PSNL at $42.6 million in Q4 2025, $7.2 million in Q3 2025, and $39.0 million in Q2 2025.