Personalis (PSNL) Operating Expenses (2018 - 2026)

Personalis (PSNL) recorded quarterly Operating Expenses of $47.6 million in Q1 2026, up 314.06% quarter-over-quarter from $11.5 million in Q4 2025, and up 494.37% on a YoY basis from $8.0 million in Q1 2025.

Personalis (PSNL) Operating Expenses (2018 - 2026) Analysis & Trends

Personalis' Operating Expenses history runs 9 years deep, the most recent figure standing at $47.6 million for Q1 2026.

  • In Q1 2026, Operating Expenses rose 494.37% year-over-year to $47.6 million; the TTM figure through Mar 2026 stood at $135.9 million (up 44.39% YoY), while the FY2025 annual figure was $34.1 million, down 77.7% from the prior year.
  • Operating Expenses was $47.6 million for Q1 2026 at Personalis, up from $11.5 million in the prior quarter.
  • In the past five years, Operating Expenses ranged from a high of $49.0 million in Q3 2023 to a low of $3.3 million in Q1 2024.
  • Historically, Operating Expenses has averaged $35.1 million across 5 years, with a median of $42.0 million in 2023.
  • The sharpest annual moves came in 2024 and 2026: Operating Expenses slumped 93.32% in 2024, then soared 494.37% in 2026.
  • A 5-year view of Operating Expenses shows it stood at $48.8 million in 2022, then fell by 10.57% to $43.6 million in 2023, then declined by 20.01% to $34.9 million in 2024, then sank by 67.05% to $11.5 million in 2025, then jumped by 314.06% to $47.6 million in 2026.
  • The last three Operating Expenses figures came in at $47.6 million (Q1 2026), $11.5 million (Q4 2025), and $37.8 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Waters 29,902.70 Bn 29,902.24 Bn 1.11 Bn 1.31 Bn
2 Thermo Fisher Scientific 175.99 Bn 172.74 Bn 7.74 Bn 9.14 Bn
3 Danaher 129.87 Bn 124.18 Bn 3.59 Bn 2.25 Bn
4 Idexx Laboratories 44.75 Bn 44.55 Bn 722.74 Mn 360.15 Mn
5 Agilent Technologies 37.52 Bn 35.72 Bn 990.00 Mn 1.44 Bn
6 Iqvia Holdings 30.91 Bn 28.94 Bn 1.36 Bn 553.00 Mn
7 Natera 30.21 Bn 29.11 Bn 696.04 Mn 790.16 Mn
8 Illumina 24.19 Bn 23.04 Bn 721.00 Mn 512.00 Mn
9 Mettler Toledo International 23.12 Bn 23.06 Bn 555.82 Mn 316.87 Mn
10 Personalis 1.05 Bn 819.64 Mn 281,000.00 47.63 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 47.63 Mn
Dec 31, 2025 11.50 Mn
Sep 30, 2025 37.79 Mn
Jun 30, 2025 39.01 Mn
Mar 31, 2025 8.01 Mn
Dec 31, 2024 34.91 Mn
Sep 30, 2024 11.74 Mn
Jun 30, 2024 39.47 Mn
Mar 31, 2024 3.25 Mn
Dec 31, 2023 43.65 Mn
Sep 30, 2023 49.04 Mn
Jun 30, 2023 42.05 Mn
Mar 31, 2023 48.69 Mn
Dec 31, 2022 48.81 Mn
Sep 30, 2022 42.12 Mn
Jun 30, 2022 46.12 Mn
Mar 31, 2022 43.53 Mn
Dec 31, 2021 40.91 Mn
Sep 30, 2021 39.95 Mn
Jun 30, 2021 36.62 Mn